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  • Book
    Pentti M. Rautaharju.
    Summary: This book reviews the promising new electrocardiographic (ECG) predictors of cardiac morbidity and mortality with the primary objective being to evaluate gender differences in special ECG features and in ECG predictors for the risk of adverse cardiac events and to explore mechanisms for gender differences in risk predictors. The Female Electrocardiogram elucidates the emergence of gender differences in ECG features and evaluates repolarization-related ECG predictors of various clinical disease categories with a special scope to interpret the mechanism and gender differences of the findings. The author examines how the predictors of adverse cardiac events are linked to basic electrophysiological finding whenever adequate information is available in this rapidly advances realm of research. The overall goal of the book is to facilitate understanding of the mechanisms and clinical relevance of repolarization abnormalities in both clinical and epidemiological applications, and as such will be of great interest to all who manage patients using ECG whether they be cardiac electrophysiologists, clinical cardiologists, critical care physicians or any medical professional in the disciplines covered.

    Contents:
    Special Features of the female electrocardiogram
    Gender Differences Emerging During Adolescence in Heart Rate, QRS Duration and ST Elevation
    The Repolarization Model
    Conceptual Considerations
    Electrocardiographic Predictors Coronary Heart Disease Death in Women
    ECG Predictors of Atrial Fibrillation and Heart Failure
    ECG Predictors of Sudden Cardiac Death
    The Utility of the Electrocardiogram in Left Ventricular Hypertrophy
    Ventricular Conduction Defects in Women
    ST-T waveform features, QT and mortality risk
    Statistical expressions for peaked vs. flat T wave and T wave asymmetry.
    Digital Access Springer 2015
  • Article
    Sastre Castillo A, Verea H, Lahoz F, Pérez Guerrero J, Vallejo J.
    Allergol Immunopathol (Madr). 1979 Mar-Apr;7(2):141-6.
    Eight cases of hereditary angioedema, all of them with low values of C1-sterase inhibitor are analyzed. In 7 cases the C3 and C4 components of the complement were assessed; the results showed marked descent of C4. The 8 patients came from 4 different families; only 2 of them were males. Six patients presented digestive disorders, reporting colic pain, nausea and vomiting. In 1 of them the abdominal picture was the only evidence of the disease. In 5 patients the angioedema episodes occurred following traumatisms and in 3 because of emotional states. The duration of the attacks varied from several hours to six days. There was a familial history in all cases. Three of the patients had repeated episodes of pharyngolaryngeal angioedema, two of them requiring emergency tracheotomy because of suffocating crisis. Six patients were treated with Epsilon aminocaproic acid (16 to 20 gr daily) or with tranexamic acid (1 to 3 gr. daily). In 4 cases the results were excellent with either of these antifibrinolytic drugs. No side effects were observed in the tranexamic acid therapy whilst they were frequent in the treatment with Epsilon aminocaproic acid.
    Digital Access Access Options