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- BookEduardo E. Benarroch.Contents:
Central autonomic network
Anatomy and function of the peripheral autonomic system
Autonomic neurotransmission
Autonomic pharmacology
Evaluation of autonomic disorders
Neurogenic orthostatic hypotension
Postural tachycardia syndrome
Baroreflex failure
Syncope and other causes of transient loss of consciousness
Disorders of sweating
Neurogenic bladder and sexual dysfunction
Gastrointestinal dysmotility
Autonomic hyperactivity
Neurodegenerative autonomic disorders
Autonomic neuropathies
Neuropathic pain disorders with autonomic component
Autoimmune autonomic disorders
Focal disorders of the cerebral hemispheres and brainstem
Focal disorders of the spinal cord
Chronic pain disorders with autonomic features. - ArticlePierce SK, Cancro MP, Klinman NR.J Exp Med. 1978 Sep 01;148(3):759-65.In recent years antigen-specific T cells have been shown to be capable of mediating a number of diverse functions in collaboration with B cells in humoral immune responses. One of the more intriguing roles attributed to helper T cells is the promotion of the synthesis of multiple immunoglobulin isotypes by B cells in T-dependent antibody responses. The experiments presented in this report were carried out to determine if an individual antigen-specific T lymphocyte has the capability to enable the production of antibodies of multiple immunoglobulin heavy chain isotypes. We describe an experimental system which allows for the isolation and antigenic stimulation of individual helper T cells in a splenic environment which provides an excess of primary B cells for collaboration with isolated T lymphocytes. Employing this system we have demonstrated that an individual antigen-specific T lymphocyte, specific for the PR8 strain of influenza virus, has the capacity to enable primary B-cell PR8-specific antibody responses of more than a single immunoglobulin isotype. The implications made by these studies regarding the problem of genetic restrictions regulating T-cell-B-cell interaction is discussed.