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  ISRN Family Medicine

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  PubMed Central

  v. 2013-2014, 2013-14.

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  v. 2013-2014, 2013-14.
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• Article

  Vliianie nizkomolekuliarnogo faktora timusa na T-kletki krovi cheloveka. [Effect of the low molecular weight thymus factor on T-cells in human blood].

  Morozov VG, Khavinson VKh, Il'in NV.

  Zh Mikrobiol Epidemiol Immunobiol. 1978 Jul(7):61-5.

  Lowmolecular factor of polypeptide nature (thymarin) was extracted from calf thymus. This factor differed by physical and chemical characteristics from thymosin. The percentage content of "active" T-lymphocytes increased under the effect of thymarin in the cultures of lymphoid cells obtained from healthy individuals. The total T-cell count remained unchanged. Thymarin favoured increase of the total T-lymphocyte and "active" T-lymphocyte count in the cultures of cells from patients with chronic inflammatory processes. Cellular immunity reactions were restored and the course of the main disease improved under the effect of parenteral administration of thymarin. It is supposed that T-immunity system incompetence was associated with the inadequate production of the thymus factor capable of restoring the activity of the thymus-dependent lymphocyte population.

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