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  Annales Instituti Obstetricil Et Gynecologici Universitatis Helsinkiensis

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  v. 3, 6-13, 17-21, 1927, 1930-37, 1941-45.

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• Article

  1-N HAPA gentamicin B, a new aminoglycoside active against gentamicin resistant isolates--activity compared to other aminoglycosides.

  Neu HC, Fu KP.

  J Antibiot (Tokyo). 1978 May;31(5):385-93.

  1-N HAPA gentamicin B is a new aminoglycoside active against most Enterobacteriaceae, Pseudomonas aeruginosa and Staphylococcus aureus. Among 504 clinical isolates at a concentration of 12.5 microgram/ml all Staph. aureus, Escherichia coli, Klebsiella, Enterobacter, Proteus rettgeri, Providencia and 78% of Pseudomonas, 86% of Proteus morganii were inhibited. Like other aminoglycosides, the activity was greatest at an alkaline ph and reduced by high cations concentrations. 1-N HAPA gentamicin B was equal in activity to amikacin against both gentamicin-sensitive and resistant isolates. It inhibited bacteria containing many of the aminoglycoside inactivating enzymes. When combined with carbenicillin it inhibited in a synergistic manner many Gram-negative bacteria, particularly Pseudomonas and Serratia.

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• Book

  Suicide ou survie de l'Occident? : Dossier pour comprendre les problèmes de ce temps.

  Lebret, Louis Joseph.

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