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- ArticleAlmange C, Lebrestec T, Louvet M, Courgeon P, Guerin D, Leborgne P.Sem Hop. 1978 Dec 18-25;54(45-46):1419-24.Metastatic tumors of the heart are often asymptomatic but they may dominate the clinical picture. The location in the interventricular septum can account for conduction disturbances. The authors report a case of esophagus neoplasm with septal metastasis responsible for a complete atrioventricular block. The histologic study of the bundle of His by serial sections showing the destruction of the conduction fibres by malignant elements has not been carried out till now except in some observations. The prognostic of the atrioventricular metastatic block is very poor; the ten months' survival which was observed in the reported case is one of the most extended in literature.