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- ArticleSawaki S, Kawamura A, Tachibana T.IARC Sci Publ (1971). 1978(20):575-85.The prognosis of a NPC patient is influenced by many factors, including the therapeutic method used and the clinical stage and histological characteristics of the tumour. The immune response of the peripheral lymphocytes was examined in 27 patients with NPC, and it was concluded that this response accurately indicates the clinical course of the diseases as compared with clinical stage of disease, histological type of tumour and anti-VCA-antibody titre.