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  • Article
    He Y, Leng J, Li K, Xu K, Lin C, Yuan Z, Zhang R, Wang D, Tao B, Huang TJ, Cai K.
    Biomaterials. 2021 11;278:121164.
    Bacterial infection treatment and subsequent tissue rebuilding are the main tasks of biomaterial research. To endow implants with antibacterial activity and biological functions, the material systems are usually very complicated and ineffective. Recently, the concept of photobiomodulation (PBM), or low-level laser therapy (LLLT), has attracted increasing attention in tissue repair applications but still has not obtained wide acceptance. Because of the same laser resource, PBM could simultaneously work with 660 nm laser triggered photodynamic therapy (PDT), which will significantly simplify the material system and achieve the multiple functions of antibacterial activity and biological modulation effects. Herein, we attempt to validate the effectiveness of PBM and combine PBM with a PDT-based material system. A catechol motif-modified methacrylated gelatin containing photosensitizer Chlorin e6-loaded mesoporous polydopamine nanoparticles was fabricated (GelMAc/MPDA@Ce6). This hydrogel could be tightly adhered to titanium surfaces to serve as surface coating materials or directly used as dressings. Because of the 660 nm laser-triggered ROS generation property of Ce6, GelMAc/MPDA@Ce6 exhibited a remarkable and rapid antibacterial activity when the laser power was 1 W cm-2. After bacterial elimination, when the power was adjusted to 100 mW cm-2, daily irradiation brought an excellent PBM effect: the fibroblast activation was realized to accelerate wound repair. According to our in vitro and in vivo results, the fabricated hydrogel coating possessed both antibacterial activity and fibroblast activation ability only by adjusting the power of laser irradiation, which will greatly strengthen the confidence of using PBM in broader fields and give a good example to combine PBM with traditional biomaterial design.
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  • Article
    Wei YF, Wu MX, Wei XR, Sun R, Xu YJ, Ge JF.
    Talanta. 2020 Oct 01;218:121164.
    Two probes based on tetrahydroxanthylium unit (probe 1a) and methyltetrahydroxanthylium unit (probe 1b) were designed and synthesized for the detection of hydrazine. Probes 1a-b exhibited turn-on red emission signal and high selectivity toward NH2NH2. The response time of probe 1a to NH2NH2 was more than 60 min, while that of probe 1b was less than 30 min. The detection limits of probes 1a-b were calculated as 210 nM and 110 nM respectively. What's more, the tolerance experiments showed that methyltetrahydroxanthylium unit possessed higher tolerance toward nucleophiles. Moreover, cells imaging experiments demonstrated that probe 1b could detect exogenous NH2NH2 in living HeLa cells.
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  • Article
    Zhao W, Wang D, Liu X, Zheng J, Liang W, Shen H, Ge X, Hu Y, Li W.
    Carbohydr Polym. 2023 Nov 01;319:121164.
    In this study, granular cold-water swelling (GCWS) starch was prepared from chestnut starch by ethanol-alkali method, after which it was further modified by electron beam irradiation (EBI) technique to investigate the effect of EBI on GCWS chestnut starch. It was shown that the alcohol-alkali treatment disrupted the starch double helix structure and the starch crystalline form had been changed from "C" to "V" type. On this basis, EBI continued to act on the disrupted starch chains and further cleaved the long chains into short chains, which significantly improved the solubility of starch to 90.08 % in cold water at a 24 kGy irradiation dose. Therefore, this study can broaden the application scope of starch and provide new ideas for GCWS starch applications in food and water-soluble pharmaceutical industries.
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  • Article
    Lu XM, Lu PZ.
    J Hazard Mater. 2020 02 05;383:121164.
    Estuary sediments are chemically contaminated by adjacent coastal industrial cities, but the impact of organic pollutants on antibiotic resistance genes (ARGs) in estuarine sediments is unknown. We comprehensively analyzed the complex interactions between chemical pollutants (heavy metals and organic pollutants), mobile genetic elements (MGEs), and ARGs in estuarine sediments during various seasons. The results indicate that under the effects of the chemically polluted river water, the number of different estuarine sediment ARGs increased by 76.9%-92.3% in summer and 5.9%-35.3% in winter, and the abundance of these ARGs increased by 29-5195 times in summer and 48-239 times in winter. The abundance of sediment ARGs in distinct estuaries showed different seasonal trends. Seasonal changes had a greater impact on the abundance of estuarine sediment ARGs than on their diversity. The diversity of estuarine sediment ARGs was positively correlated with the chemical pollution levels. Furthermore, chemical pollution was positively correlated with MGEs, and MGEs were correlated with ARG abundance. These results indicate that ARGs are enriched in bacteria via horizontal gene transfer triggered by chemical pollution, promoting multi-antibiotic resistance in estuarine sediment bacteria. These findings have implications for our understanding of the distribution and propagation of ARGs in chemically polluted estuarine sediments.
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  • Article
    Marangon BB, Castro JS, Assemany PP, Machado NA, Calijuri ML.
    J Environ Manage. 2024 Jun;360:121164.
    The present paper compared, through life cycle assessment (LCA), the production of aviation biofuel from two hydrothermal routes of microalgae cultivated in wastewater. Hydrothermal liquefaction (HTL) and gasification followed by Fischer-Tropsch synthesis (G + FT) were compared. Both routes included biomass production, hydrotreatment for biofuel upgrading, and product fractionation. Secondary data obtained from the literature were used for the cradle-to-gate LCA. G + FT had a higher impact than HTL in the 18 impact categories assessed, with human carcinogenic toxicity exerting the most harmful pressure on the environment. The catalysts were the inputs that caused the most adverse emissions. The solvent used for bio-oil separation also stood out in terms of impacts. In HTL, emissions for global warming were -51.6 g CO2 eq/MJ, while in G + FT, they were 250 g CO2 eq/MJ. At the Endpoint level, HTL resulted in benefits to human health and ecosystems, while G + FT caused environmental damage in these two categories, as well as in the resources category. In the improvement scenarios, besides considering solid, aqueous, and gaseous products as co-products rather than just as waste/emissions, a 20% reduction in catalyst consumption and 90% recovery were applied. Thus, in HTL, 39.47 kg CO2 eq was avoided, compared to 35.44 kg CO2 eq in the base scenario. In G + FT, emissions decreased from 147.55 kg CO2 eq to the capture of 8.60 kg CO2 eq.
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  • Article
    Abulaiti A, She D, Pan Y, Shi Z, Hu L, Huang X, Shan J, Xia Y.
    Water Res. 2024 Mar 01;251:121164.
    Agriculture is a main source of nitrous oxide (N2O) emissions. In agricultural systems, direct N2O emissions from nitrogen (N) addition to soils have been widely investigated, whereas indirect emissions from aquatic ecosystems such as ditches are poorly known, with insufficient data available to refine the IPCC emission factor. In this contribution, in situ N2O emissions from two ditch water‒air interfaces based on a diffusion model were investigated (almost once per month) from June 2021 to December 2022 in an intensive arable catchment with high N inputs and salt-affected conditions in the Qingtongxia Irrigation District, northwestern China. Our results implied that agricultural ditches (mean 148 μg N m-2 h-1) were significant sources for N2O emissions, and were approximately 2.1 times greater than those of the Yellow River directly connected to ditches. Agronomic management strategies increased N2O fluxes in summer, while precipitation events decreased N2O fluxes. Agronomic management strategies, including fertilization (294--540 kg N hm-2) and irrigation on farmland, resulted in enhanced diffuse N loads in drain water, whereas precipitation diluted the dissolved N2O concentration in ditches and accelerated the ditch flow rate, leading to changes in the residence time of N-containing substances in water. The spatial analysis showed that N2O fluxes (202-233 μg N m-2 h-1) in the headstream and upstream regions of ditches due to livestock and aquaculture pollution sources were relatively high compared to those in the midstream and downstream regions (100-114 μg N m-2 h-1). Furthermore, high available carbon (C) relative to N reduced N2O fluxes at low DOC:DIN ratio levels by inhibiting nitrification. Spatiotemporal variations in the N2O emission factor (EF5) across ditches with higher N resulted in lower EF5 and a large coefficient of variation (CV) range. EF5 was 0.0011 for the ditches in this region, while the EF5 (0.0025) currently adopted by the IPCC is relatively high. The EF5 variation was strongly controlled by the DOC:DIN ratio, TN, and NO3--N, while salinity was also a nonnegligible factor regulating the EF5 variation. The regression model incorporating NO3--N and the DOC:DIN ratio could greatly enhance the predictions of EF5 for agricultural ditches. Our study filled a key knowledge gap regarding EF5 from agricultural ditches in salt-affected farmland and offered a field investigation for refining the EF5 currently used by the IPCC.
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  • Article
    Wang A, Sun Y, Sun Z, Liu X, Yu X, Li K, Zhang X, Xu Y, Mu W, Li B.
    Environ Pollut. 2023 Apr 01;322:121164.
    The behavior of pesticide particles or droplets might significantly influence their environmental risks. However, studies on the risk of different pesticide formulations in aqueous environments have rarely been reported. In this study, we prepared three types of pyraclostrobin formulations to evaluate their behavior in the aqueous environment and toxicological risks to zebrafish. The results showed that pyraclostrobin emulsifiable concentrate (EC) sank faster in water with increasing hydrophilicity and density of the solvent. The particles also sank faster with increasing particle size and particle density for suspension concentrate (SC) and microcapsules (MCs). Diverse behavior in water results in different temporal and spatial distributions of the active ingredient. EC-EGDA, SC-5 μm, CS-Large and EC-MO sink or float over time, therefore reducing the effective dose suspended in water. Lower toxicological risks of the pesticides were also observed by reducing the enrichment of pyraclostrobin in zebrafish. In addition to the direct toxicity of the active ingredient, the type of pesticide formulations and their specific compositions might also influence the integrated toxicity. The environmental behavior of pesticide formulations should also be considered for their systematic assessment of environmental risks to ensure the scientific application of pesticides in different scenarios.
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  • Article
    Wei H, Chen X, Zong X, Shu H, Gao D, Liu Q.
    PLoS One. 2015;10(3):e0121164.
    BACKGROUND: Fruit color is one of the most important economic traits of the sweet cherry (Prunus avium L.). The red coloration of sweet cherry fruit is mainly attributed to anthocyanins. However, limited information is available regarding the molecular mechanisms underlying anthocyanin biosynthesis and its regulation in sweet cherry.
    METHODOLOGY/PRINCIPAL FINDINGS: In this study, a reference transcriptome of P. avium L. was sequenced and annotated to identify the transcriptional determinants of fruit color. Normalized cDNA libraries from red and yellow fruits were sequenced using the next-generation Illumina/Solexa sequencing platform and de novo assembly. Over 66 million high-quality reads were assembled into 43,128 unigenes using a combined assembly strategy. Then a total of 22,452 unigenes were compared to public databases using homology searches, and 20,095 of these unigenes were annotated in the Nr protein database. Furthermore, transcriptome differences between the four stages of fruit ripening were analyzed using Illumina digital gene expression (DGE) profiling. Biological pathway analysis revealed that 72 unigenes were involved in anthocyanin biosynthesis. The expression patterns of unigenes encoding phenylalanine ammonia-lyase (PAL), 4-coumarate-CoA ligase (4CL), chalcone synthase (CHS), chalcone isomerase (CHI), flavanone 3-hydroxylase (F3H), flavanone 3'-hydroxylase (F3'H), dihydroflavonol 4-reductase (DFR), anthocyanidin synthase (ANS) and UDP glucose: flavonol 3-O-glucosyltransferase (UFGT) during fruit ripening differed between red and yellow fruit. In addition, we identified some transcription factor families (such as MYB, bHLH and WD40) that may control anthocyanin biosynthesis. We confirmed the altered expression levels of eighteen unigenes that encode anthocyanin biosynthetic enzymes and transcription factors using quantitative real-time PCR (qRT-PCR).
    CONCLUSIONS/SIGNIFICANCE: The obtained sweet cherry transcriptome and DGE profiling data provide comprehensive gene expression information that lends insights into the molecular mechanisms underlying anthocyanin biosynthesis. These results will provide a platform for further functional genomic research on this fruit crop.
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  • Article
    Song Y, Qin M, Liu S, Gao Y, Li B, Lin L, Wang CK, Fan J.
    Spectrochim Acta A Mol Biomol Spectrosc. 2022 Jul 05;275:121164.
    Circularly polarized luminescence (CPL) molecules with thermally activated delayed fluorescence (TADF) features show promising applications in high-efficiency circularly polarized organic light emitting diodes (CP-OLEDs). Herein, a pair of chiral molecules (R)-ImNT and (S)-ImNT are studied, two kinds of conformations are found by molecular dynamic conformation search, namely the quasi-axial and the quasi-equatorial conformations. Moreover, molecule with quasi-axial conformation is conducive to achieve outstanding CPL properties due to the large contributions of chiral groups to natural transition orbitals. While the energy gaps for quasi-equatorial conformations are significantly reduced and spin-orbit coupling effects between them are obviously increased. In addition, the quasi-equatorial configuration can facilitate the reverse intersystem crossing process to achieve remarkable TADF feature. Relationships between molecular geometries and CPL as well as TADF properties are revealed. Our research elucidates the relationship between geometric structure and luminescence mechanism, which could provide valuable insights for the design of efficient CPL-TADF emitters.
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  • Book
    edited by Teresa L. Thompson, Nancy Grant Harrington.
    Summary: "A seminal text in the field, this new edition of The Routledge Handbook of Health Communication provides students and scholars with a comprehensive survey of the subject's key research foundations and trends, authored the by discipline's leading scholars. The third edition has been completely updated and reorganized to guide both new researchers and experienced scholars through the most critical and contemporary topics in health communication today. There is new attention to policy and NGOs, marginalized populations such as migrants and refugees, the environment, global health, and health advocacy and activism. The handbook will continue to serve as an invaluable resource for students, researchers, scholars, policymakers, and healthcare professionals doing work in health communication"-- Provided by publisher.

    Contents:
    Section I. Introduction
    Chapter 1. The Multidisciplinary, Interdisciplinary, and Transdisciplinary Nature of Health Communication Scholarship / by Elisia L. Cohen
    Chapter 2. Theoretical and Methodological Matters in Health Communication Navigating Current and Future Directions / by Nancy Grant Harrington, Diane B. Francis, Aurora Occa
    Chapter 3. Research Translation, Dissemination, and Implementation / by Janice L. Krieger, Donghee Lee, Melissa J. Vilaro, Danyell Wilson-Howard, Aantaki Raisa, Yewande O. Addie
    Chapter 4. Narrative Features, Forms, and Functions Telling Stories to Foster Well-Being, Humanize Healthcare, and Catalyze Change / by Lynn M. Harter, Jill Yamasaki, Anna M. Kerr
    Section II. Interpersonal and Family Health Communication
    Chapter 5. Mental Health, Mental Illness, and Suicide / by Rosalie S. Aldrich, Jessie M. Quintero Johnson
    Chapter 6. Stigma, Communication, and Health / by Xun Zhu, Rachel A. Smith
    Chapter 7. Health and Relational Outcomes for Informal Caregivers and Care-Recipients / by Jacquelyn Harvey, Meara H. Faw, Elizabeth S. Parks
    Chapter 8. Family Health Communication / by Maureen P. Keeley, Lauren Lee
    Chapter 9. Palliative Care and End-of-Life Communication / by Elaine Wittenberg, Joy V. Goldsmith
    Chapter 10. Social Support, Supportive Communication, and Health / by Erina L. MacGeorge, Yanmengqian Zhou
    Chapter 11. Everyday Interpersonal Communication About Health and Illness / by Katharine J. Head, Jennifer J. Bute, Katherine E. Ridley-Merriweather
    Section Section III. Patient-Provider Communication
    Chapter 12. Mutual Persuasion as Patient-Centered Communication / by Jennifer Freytag, Richard L. Street
    Chapter 13. Difficult Conversations Between Healthcare Providers and Patients / by Allison M. Scott
    Chapter 14. Improving Clinician and Patient Communication Skills / by Brianna R. Cusanno, Nivethitha Ketheeswaran, Carma L. Bylund
    Chapter 15. Patient-Provider Communication and Health Outcomes / by Kelly Haskard-Zolnierek, Morgan Snyder, Rabecca-Kimberly Hernandez, Teresa L. Thompson
    Section IV. Healthcare Provider and Organizational Health Communication
    Chapter 16. The Multiple Voices of Communication in Healthcare / by Margaret F. Clayton, Pearman D. Parker, Lee Ellington
    Chapter 17. Interprofessional Communication Healthcare Teams, Patient Handoffs, and Multiteam Systems / by Kevin Real, Anne Ray Streeter, Marshall Scott Poole
    Chapter 18. Stress and Burnout A Review of Research in Health Organizations / by Jennifer Ptacek, Julie Apker
    Section Section V . Mediated Communication
    Chapter 19. Health and Media The Impact of News and Entertainment / by Katherine A. Foss
    Chapter 20. Consumer Advertising and Health Communication / by Michael Mackert, Deena Kemp, Daniela De Luca, Rachel Esther Lim. Chapter 21. Social Media and Health / by Yan Tian, James D. Robinson
    Chapter 22. Health Misinformation / by Xiaoli Nan, Yuan Wang, Kathryn Thier
    Section Section VI. Campaigns, Interventions, and Technology Applications
    Chapter 23. Public Health Communication Campaigns / by Kami J. Silk, Tara L. Smith, Charles T. Salmon, Brandon D. H. Thomas, Thanomwong Poorisat
    Chapter 24. Community-Based Health Interventions / by Taylor Goulbourne, Charles R. Senteio, Kathryn Greene, Itzhak Yanovitzky
    Chapter 25. Technology-Based Interventions for Health Promotion and Disease Prevention and Treatment / by Jessica Fitts Willoughby
    Chapter 26. The Role of Technology in Health Communication Trends and Trajectories / by Ronald E. Rice, S. Shyam Sundar, Hyang-Sook Kim
    Section VII. Overarching Issues in Health Communication
    Chapter 27. Health Information Seeking / by Nehama Lewis, Nancy Shekter-Porat, Huda Nasir
    Chapter 28. Inroads Into Healthy Decision-Making The Role of Health Literacy in Health Communication / by Sarah A. Aghazadeh, Linda Aldoory
    Chapter 29. Communication, Health, and Equity Structural Influences / by Kasisomayajula Viswanath, Rachel F. McCloud, Mesfin A. Bekalu
    Chapter 30. Intercultural Health Communication Rethinking Culture in Health Communication / by Elaine Hsieh
    Chapter 31. Global Health Communication / by J. Douglas Storey MB
    Chapter 32. Public Health Crises / by Lindsay Neuberger, Ann Neville Miller
    Chapter 33. Communicating About the Environment and Health 1 / by Amy E. Chadwick
    Section VIII. Challenges and Challenging Contexts in Health Communication Research and Practice
    Chapter 34. Ethical Issues in Health Communication in Clinical and Digital Settings and in Health Communication Campaigns / by Nurit Guttman, Eimi Lev, Maram Khazen
    Chapter 35. Rethinking Imbalances of Power Through Health Communication Challenges for Scholars, Practitioners, and Activists / by Angela Cooke-Jackson, Andrew Spieldenner, Nicole Hudak, Crystal Ben
    Chapter 36. Conversation Analysis and Health Communication / by Kristella Montiegel, Jeffrey D. Robinson
    Chapter 37. Advancing Health Communication Research Issues and Controversies in Research Design and Data Analysis / by Ilona Fridman, Brian G. Southwell, Marco Yzer, Michael T. Stephenson
    Chapter 38. Health Communication Research and Practice at the Level of Government, Foundations, Public Policy, and NGOs 1 / by Bradford W. Hesse
    Chapter 39. Challenges in Conducting Health Communication Research / by Amy Koerber, Avinash Thombre.
    Digital Access TandFonline 2021
doi:10.1016/j.biomaterials.2021.121164 doi:10.1016/j.talanta.2020.121164 doi:10.1016/j.carbpol.2023.121164 doi:10.1016/j.jhazmat.2019.121164 doi:10.1016/j.jenvman.2024.121164 doi:10.1016/j.watres.2024.121164 doi:10.1016/j.envpol.2023.121164 doi:10.1371/journal.pone.0121164 doi:10.1016/j.saa.2022.121164