Books

1. History of the J wave and J wave Syndromes -- 2. J wave Syndromes: from Bench to Bedside -- 3. Ionic and Cellular Mechanisms Underlying J wave Syndromes -- 4. Genetic Basis of Early Repolarization Syndrome -- 5. J wave Syndrome-Susceptibility Mutations Versus Benign Rare Variants: How do We Decide? -- in the Electrocardiographic and Clinical Feature between Early Repolarization Syndrome and Brugada Syndrome -- 12. Atrial Arrhythmias Associated with J wave Syndromes -- 13. Phenotypic Expression and Genetics of J wave Syndrome in the Early Stage of Arrhythmogenic Right Ventricular Cardiomyopathy -- 14. Clinical Features of Electrical Storms Associated with J wave Syndromes and Acquired Forms of J wave Syndrome -- 15. Therapy for J wave Syndromes -- 16. J wave Syndromes in China.

"Using the popular JAAPA Quick Recertification Series (QRS) format developed by PAs for PAs, this unique review presents up-to-date coverage of all certification and recertification topics, including preventive medicine, identification and treatment of illness, and diagnostic testing, accompanied by pre-and post-tests that help readers easily assess their knowledge and target areas for further study. This approach, designed by learning experts in partnership with leading clinicians and PA faculty, has been used successfully for more than a decade and is tailored for PAs. Combined with hands-on study tools and proven techniques to maximize learning and test-taking, this resource not only prepares students and PAs for success on the PANCE and PANRE but helps users self-assess their baseline knowledge and save time in preparation for any exam."--Amazon.com.

"Often referred to as the mirror of the soul, the face is indelibly entwined with a person's appearance and personality. This presents a particular challenge when reconstructive surgery is required. The goal of every reconstructive surgeon is to repair damage as inconspicuously as possible with minimal scarring while restoring prior function. Jackson's Local Flaps in Head and Neck Reconstruction, Third Edition by renowned plastic surgeons Peter C. Neligan, J. Brian Boyd, and David Mathes honors the two widely acclaimed prior editions of this landmark resource by the late master plastic surgeon, educator, and prolific author Ian T. Jackson. The new edition features updated and streamlined content, simplified references, colorized illustrations, and procedural videos"-- Provided by publisher.

Analysis of Janus tyrosine kinase phosphorylation and activation / Jeremy A. Ross, Georgialina Rodriguez, and Robert A. Kirken -- Co-immunoprecipitation protocol to investigate cytokine receptor-associated proteins, e.g., Janus kinases or other associated signaling proteins / Claude Haan and Serge Haan -- In vitro JAK kinase activity and inhibition assays / Jeffrey J. Babon and James M. Murphy -- Quantitative analysis of JAK binding using isothermal titration calorimetry and surface plasmon resonance / Jeffrey J. Babon -- Determination of protein turnover rates in the JAK/STAT pathway using a radioactive pulse-chase approach / Anna Dittrich, Elmar Siewert, and Fred Schaper -- Designing RNAi screens to identify JAK/STAT pathway components / Katherine H. Fisher, Stephen Brown, and Martin P. Zeidler -- The use of JAK-specific inhibitors as chemical biology tools / Christopher J. Burns, David Segal, and Andrew F. Wilks -- Methods for detecting mutations in the human JAK2 gene / Anthony J. Bench, E. Joanna Baxter, and Anthony R. Green -- Detection of activated STAT proteins / Jean-Patrick Parisien and Curt M. Horvath -- Detection of activated STAT species using electrophoretic mobility shift assay (EMSA) and potential pitfalls arising from the use of detergents / Serge Haan and Claude Haan -- Flow cytometric analysis of STAT phosphorylation / Jane Murphy and Gabrielle L. Goldberg -- Acetylation of endogenous STAT proteins / Torsten Ginter, Thorsten Heinzel, and Oliver H. Krämer -- Detection and cellular localization of phospho-STAT2 in the central nervous system by immunohistochemical staining / Reza Khorooshi and Trevor Owens -- Nuclear trafficking of STAT proteins visualized by live cell imaging / Velasco Cimica and Nancy C. Reich -- Characterization of STAT self-association by analytical ultracentrifugation / Nikola Wenta and Uwe Vinkemeier -- Constitutively active STAT5 constructs / Lynn M. Heltemes-Harris and Michael A. Farrar -- Analysis of suppressor of cytokine signalling (SOCS) gene expression by real-time quantitative PCR / Tatiana B. Kolesnik and Sandra E. Nicholson -- Detection of endogenous SOCS1 and SOCS3 proteins by immunoprecipitation and western blot analysis / Jian-Guo Zhang and Sandra E. Nicholson -- In vitro ubiquitination and cytokine signaling components / Jeffrey J. Babon, Artem Laktyushin, and Nadia J. Kershaw -- Production and crystallization of recombinant JAK proteins / Isabelle S. Lucet and Rebecca Bamert -- Bacterial expression, purification, and crystallization of tyrosine phosphorylated STAT proteins / Florence Baudin and Christoph W. Müller.

Janeway's Immunobiology is a textbook for students studying immunology at the undergraduate, graduate, and medical school levels. As an introductory text, students will appreciate the book's clear writing and informative illustrations, while advanced students and working immunologists will value its comprehensive scope and depth. Janeway's Immunobiology presents immunology from a consistent point of view throughout--that of the host's interaction with an environment full of microbes and pathogens. The Ninth Edition has been thoroughly revised bringing the content up-to-date with significant developments in the field, especially on the topic of innate immunity, and improving the presentation of topics across chapters for better continuity. -- Provided by publisher.

Immunobiology is the premier text for immunology at the advanced undergraduate, graduate, and medical school levels. Beginning students appreciate the book's clear writing and informative illustrations, while advanced students and working immunologists value its comprehensive scope. Every chapter is reviewed with experts to ensure accuracy, authority, currency, and depth. The Tenth Edition is supported by InQuizitive, Norton's award-winning, easy-to-use adaptive learning tool that helps students learn immunological terms and apply them conceptually. -- Provided by publisher.

This book gives an overview of the diverse marine fauna and flora of Japan and includes practical guides for investigating the biology and ecology of marine organisms. Introducing marine training courses offered at a range of Japanese universities, this is the first English textbook intended for marine biology instructors and students in Japan. It provides essential information on experimental procedures for the major areas of marine biology, including cell and developmental biology, physiology, ecology and environmental sciences, and as such is a valuable resource for those in Asian countries that share a similar flora and fauna. It also appeals to visitors interested in attending Japanese marine courses from countries around the world. .

Phenotyping jasmonate regulation of senescence / Martin A. Seltmann and Susanne Berger -- Characterizing jasmonate regulation of male fertility in Arabidopsis / Bryan Thines, Ajin Mandaokar, and John Browse -- Phenotyping jasmonate regulation of root growth / Fabian Kellermeier and Anna Amtmann -- Bioassays for assessing jasmonate-dependent defenses triggered by pathogens, herbivorous insects, or beneficial Rhizobacteria / Saskia C.M. Van Wees ... [et al.] -- Elicitation of jasmonate-mediated defense responses by mechanical wounding and insect herbivory / Marco Herde, Abraham J.K. Koo, and Gregg A. Howe -- Pseudomonas syringae infection assays in Arabidopsis / Jian Yao, John Withers, and Sheng Yang He -- Jasmonate signaling in the field, part I : elicited changes in jasmonate pools of transgenic Nicotiana attenuata / Emmanuel Gaquerel ... [et al.] -- Jasmonate Signaling in the field, part II : insect-guided characterization of genetic variations in jasmonate-dependent defenses of transgenic and natural Nicotiana attenuata populations / Emmanuel Gaquerel ... [et al.] -- Profiling of jasmonic acid-related metabolites and hormones in wounded leaves / Yusuke Jikumaru -- Non-targeted approach for extended liquid chromatography-mass spectrometry profiling of free and esterified jasmonates after wounding / Gaëtan Glauser and Jean-Luc Wolfender -- Cell-specific detection of jasmonates by means of an immunocytological approach / Bettina Hause, Kati Mielke, and Susanne Forner -- Jasmonic acid-amino acid conjugation enzyme assays / Martha L. Rowe and Paul E. Staswick -- Pull-down analysis of interactions among jasmonic acid core signaling proteins / Sandra Fonseca and Roberto Solano -- Yeast two-hybrid analysis of jasmonate signaling proteins / Amparo Pérez Cuéllar ... [et al.] -- Modified bimolecular fluorescence complementation assay to study the inhibition of transcription complex formation by JAZ proteins / Tiancong Qi, Susheng Song, and Daoxin Xie -- Agroinfiltration of Nicotiana benthamiana leaves for co-localization of regulatory proteins involved in jasmonate signaling / Volkan Çevik and Kemal Kazan -- Electrophoretic mobility shift assay for the analysis of interactions of jasmonic acid-responsive transcription factors with DNA / Johan Memelink -- Transient expression assays in tobacco protoplasts / Robin Vanden Bossche ... [et al.] -- Functional analysis of jasmonic acid-responsive secondary metabolite transporters / Nobukazu Shitan, Akifumi Sugiyama, and Kazufumi Yazaki -- Expression analysis of jasmonate-responsive lectins in plants / Nausicaä Lannoo and Els J.M. Van Damme -- Profiling the jasmonic acid responses by nuclear magnetic resonance-based metabolomics / Hye Kyong Kim, Young Hae Choi, and Robert Verpoorte -- Metabolite profiling of plant tissues by liquid chromatography fourier transform ion cyclotron resonance mass spectrometry / Jacob Pollier and Alain Goossens -- cDNA-AFLP-based transcript profiling for genome-wide expression analysis of jasmonate-treated plants and plant cultures / Janine Colling ... [et al.] -- Analysis of RNA-seq data with TopHat and cufflinks for genome-wide expression analysis of jasmonate-treated plants and plant cultures / Jacob Pollier, Stephane Rombauts, and Alain Goossens -- Transcriptome coexpression analysis using ATTED-II for integrated transcriptomic/metabolomic analysis / Keiko Yonekura-Sakakibara and Kazuki Saito -- Guide to CORNET for the construction of coexpression and protein-protein interaction networks / Stefanie De Bodt and Dirk Inzé.

Introduction -- Basic principles of head and neck surgery -- Scalp and skin -- Eyelids and orbit -- Nasal cavity and paranasal sinuses -- Skull base -- Lips -- Oral cavity -- Pharynx and esophagus -- Larynx and trachea -- Cervical lymph nodes -- Thyroid and parathyroid glands -- Salivary glands -- Neurogenic tumors and paragangliomas -- Soft tissue tumors -- Bone tumors, including odontogenic lesions -- Reconstructive surgery -- Oncologic dentistry, maxillofacial prosthetics, and implants -- Radiation therapy -- Systemic therapy.

Jatropha curcas, or physic nut, is a small tree that, in tropical climates, produces fruits with seeds containing ~38% oil. The physic nut has the potential to be highly productive and is amenable to subculture in vitro and to genetic modification. It also displays remarkable diversity and is relatively easy to cross hybridize within the genus. Thanks to these promising features, J. curcas is emerging as a promising oil crop and is gaining commercial interest among the biofuel research communities. However, as a crop, physic nut has been an economic flop since 2012, because the species was not fully domesticated and the average productivity was less than 2 t/ha, which is below the threshold of profitability. Nevertheless, hybrids with a productivity of>7 t/ha could be reached and it is contributing to new markets in some countries. As such, it is important fro research to focus on the physiology and selective breeding of Jatropha . This book provides a positive global update on Jatropha, a crop that has suffered despite its promising agronomic and economic potential. The editors have used their collective expertise in agronomy, botany, selective breeding, biotechnology, genomics and bioinformatics to seek out high-quality contributions that address the bottleneck features in order to improve the economic trajectory of physic nut breeding.

Primitive big mouths to modern malocclusion -- Mostly chewing -- The diet, posture, and housing revolutions -- Appearance -- Development and oral posture -- Disorders of breathing and sleep -- What can you do? -- Orthodontists, dental orthopedists, orthotropists, and forwardontists -- Changing culture, improving health.

The exhibition covers the painter's whole career, from 1980 to 1988, focusing on 120 defining works. With the Heads from 1981-1982, gathered for the first time here, and the presentation of several collaborations between Basquiat and Warhol, the exhibition includes works previously unseen in Europe, essential works such as Obnoxious Liberals (1982), In Italian (1983), and Riding with Death (1988), as well as paintings which have rarely been seen since their first presentations during the artist's lifetime, such as Offensive Orange (1982), Untitled (Boxer) (1982), and Untitled (Yellow Tar and Feathers) (1982). At a young age, Jean-Michel Basquiat left school and made his first studio in the streets of New York. Very quickly, his painting achieved great success, which the artist both sought out and felt subjected to. His work refers back to the eruption of modernity, that of the expressionists, but his filiations are numerous. The acuteness of his gaze, his visits to museums, and the reading of a number of books gave him a real sense of culture. Yet his gaze was directed: the absence of black artists being painfully evident, the artist imposed the need to depict African American culture and revolts in equal measure in his work. Basquiat's death in 1988 interrupted a very prolific body of work, carried out in under a decade, with over one thousand paintings and even more drawings.--Fondation Louis Vuitton website. "Published in conjunction with the exhibition at Fondation Louis Vuitton, this catalogue captures the dazzling career of Jean-Michel Basquiat (1960-1988). Featuring reproductions of all 120 works shown, it provides a unique opportunity to re-examine the oeuvre of this seminal artist. Dieter Buchart, exhibition curator and catalogue editor, explores the existential character of Basquiat's line, among other key topics of investigation. Following a preface by Suzanne Pagé, texts by Okwui Enwezor, Olivier Michelon, Francisco Pellizzi, Jordana Moore Saggese, Paul Schimmel, and Franklin Sirmans expand on the approaches to the artist's work, contextualizing its creation, its importance within the history of twentieth-century art, and its relevance today. They address essential subjects running throughout Basquiat's oeuvre, while placing it within the critical and historical framework fundamental to its understanding." --Publisher's description, lower cover.

The quintessential reference for bedside medical management of neurocritical care patients Medical management of patients in the neurocritical care unit (NCCU) often spells the difference between life or death and return to normal function or a lifetime disability. As such, it is vital that patients with life-threatening neurological and neurosurgical illnesses receive prompt diagnosis and rapid interventions in the NCCU. The Jefferson Manual for Neurocritical Care by renowned neurosurgeon Jack I. Jallo, neurointensive care physician Jacqueline S. Urtecho, and distinguished colleagues is a hig

Jekel's Epidemiology, Biostatistics, Preventive Medicine, and Public Health is the only textbook that combines the disciplines of medical epidemiology, biostatistics, preventive medicine, and public health in one convenient resource. Written by renowned epidemiologists and public health experts, this text presents the information with a clinical focus, using real-life medical examples throughout. With review questions in each chapter to maximize knowledge retention and target key areas of review, it serves as an outstanding resource for USMLE prep - and is recommended by the American Board of Preventive Medicine as a top review source for its core specialty examination.

JIMD Reports publishes case and short research reports in the area of inherited metabolic disorders. Case reports highlight some unusual or previously unrecorded feature relevant to the disorder, or serve as an important reminder of clinical or biochemical features of a Mendelian disorder.

JIMD Reports publishes case and short research reports in the area of inherited metabolic disorders. Case reports highlight some unusual or previously unrecorded feature relevant to the disorder, or serve as an important reminder of clinical or biochemical features of a Mendelian disorder.

JIMD Reports publishes case and short research reports in the area of inherited metabolic disorders. Case reports highlight some unusual or previously unrecorded feature relevant to the disorder, or serve as an important reminder of clinical or biochemical features of a Mendelian disorder.

Declarations; Ethics Approval and Consent to Participate; Consent for Publication; Availability of Data and Material; Completing Interests; Funding; Authors ́Contributions; References; Oral Ganglioside Supplement Improves Growth and Development in Patients with Ganglioside GM3 Synthase Deficiency; Abstract; Introduction; Materials and Methods; Patients and Experimental Design; Developmental and Other Assessments; Biochemical Assays; Data Analysis and Statistics; Results; Clinical Observation; Growth; Developmental and Cognitive Evaluation; Plasma Ganglioside Levels; Discussion

Building on the strength of previous versions, the fourth edition of this foundational text is fully revised to include updated content based on more than a decade of the model's use, refinement in real-life settings, and feedback from nurses and other healthcare professionals around the world.

Written primarily by a former resident and current assistant professor at Johns Hopkins University School of Medicine, this unique handbook uses only concise bullets and tables to answer the treatment and management questions that most often arise during daily ob/gyn practice. The only ob-gyn handbook offering on-the-go guidance and step-by-step instruction for your ob-gyn rotation or clinical serviceThe Johns Hopkins Handbook of Obstetrics and Gynecology provides you with essential, easily located information to address treatment and management questions and gives you immediate guidance on difficult clinical decisions that you face in daily practice. In addition to general obstetric and gynecologic coverage, it includes the subspecialties of gynecologic oncology, reproductive endocrinology and infertility, and urogynecology.This concise book is packed with protocol-driven instruction and successfully presents complex information through the use of an outline format consisting exclusively of bullets, tables, and figures.Based on Johns Hopkins and ACOG Practice Guidelines, this carry-everywhere reference offers quick answers that you can trust when there isn't time to read a chapter, access a computer, or scan summary articles to find that one key bit of information.

I. Early years, 1867-1893.--II. 1893-1905.--III. 1905-1914.

"This fully revised third edition builds on the strength of the first two editions with updated content based on more than a decade of the model’s use and refinement in real-life settings."--Back cover.

Foundations of patient care -- Patient- and family-centered care at the Johns Hopkins hospital -- Competencies, lessons learned, and recommendations -- Empowerment through shared governance -- Shared governance in a professional practice environment -- Shared governance : competencies, lessons learned, and recommendations -- Foundations of nursing excellence -- Excellence in nursing practice at the johns hopkins hospital -- We excel : competencies, lessons learned, and recommendations -- The influence of inquiry and interprofessional collaboration in nursing -- Inquiry and interprofessional collaboration in practice -- We influence : competencies, lessons learned, and recommendations.

Part I. General thoracic surgery -- Part II. Adult Cardiac Sugery -- Part III. Congenital Cardiac Sugery.

As medical devices become more intricate, with an increasing number of components made from a wide range of materials, it is important that they meet stringent requirements to ensure that they are safe to be implanted and will not be rejected by the human body. Joining and assembly of medical materials and devices provides a comprehensive overview of joining techniques for a range of medical materials and applications. Part one provides an introduction to medical devices and joining methods with further specific chapters on microwelding methods in medical components and the effects of sterilization on medical materials and welded devices. Part two focuses on medical metals and includes chapters on the joining of shape memory alloys, platinum (Pt) alloys and stainless steel wires for implantable medical devices and evaluating the corrosion performance of metal medical device welds. Part three moves on to highlight the joining and assembly of medical plastics and discusses techniques including ultrasonic welding, transmission laser welding and radio frequency (RF)/dielectric welding. Finally, part four discusses the joining and assembly of biomaterial and tissue implants including metal-ceramic joining techniques for orthopaedic applications and tissue adhesives and sealants for surgical applications. Joining and assembly of medical materials and devices is a technical guide for engineers and researchers within the medical industry, professionals requiring an understanding of joining and assembly techniques in a medical setting, and academics interested in this field. Introduces joining methods in medical applications including microwelding and considers the effects of sterilization on the resulting joints and devicesConsiders the joining, assembly and corrosion performance of medical metals including shape memory alloys, platinum alloys and stainless steel wiresConsiders the joining and assembly of medical plastics including multiple welding methods, bonding strategies and adhesives.

This book addresses key issues in perinatal mental health and discusses the different types of psychiatric care that may be appropriate for pregnant women, parents, and infants, with emphasis on the need for joint care. The wide range of preventive measures, mainly applicable in primary care, and the various potential curative interventions are examined in detail, with coverage of ambulatory care, day care, and the role of mother and baby units. The importance of working in networks and joint decision-making strategies is explained. In addition, an overview of maternal perinatal psychopathology is provided, and other relevant aspects are fully discussed, including the establishment of parent-infant interactions and the impacts of parental psychiatric illness on parenting skills and infant development. The book will be invaluable for adult and child psychiatrists, psychologists, psychotherapists, midwives, nurses, and all others involved in the provision of perinatal psychiatric care.

Provides the basis for accreditation of hospitals throughout the world. Joint Commission International (JCI) standards define the performance expectations, structures, and functions that must be in place for a hospital to be accredited by JCI. The effective date of the 7th Edition is 1 January 2021 (extended from the originally announced date of 1 October 2020), which means all surveys that begin on or after this date will be surveyed under the 7th Edition.

This book serves as an anatomic atlas of the nerves that innervate the joints of the human body in a format that also provides technical insight into pathways that both interventional pain management and surgical subspecialists can use to denervate those painful joints when traditional approaches to manage the pain are no longer successful. This book avails the knowledge of how denervation can relieve joint pain available to the many groups of physicians who care for this problem. Each chapter is devoted to a joint and reviews the neural anatomy as it relates to the clinical examination of the patient. Chapters are user friendly and provide details on the indicated nerve blocks and the clinical results of partial joint denervation. Clinical case studies also serve as a helpful guide in each chapter. Extensive intra-operative clinical photographs and photographs from new prosections provide examples to guide those physicians providing care to the patients with joint pain. Joint Denervation: Anatomic Atlas of Surgical Technique should be of interest to surgical subspecialists from Neurosurgery, Plastic Surgery, Hand Surgery, Orthopedic Surgery, Podiatric Foot & Ankle Surgery, and Oral & Maxillofacial Surgeons. It may also interest those physicians trained in Anesthesia, Radiology, and Physical & Rehabilitation Medicine for their evaluation and treatment protocols using hydrodissection, cryoablation and pulsed radiofrequency approaches to pain.

This user-friendly, pragmatic book discusses the normal and pathological conditions of the appendicular skeleton, with a focus on the preservation of joint function, providing a detailed overview of strategies for both common and complex joint preservation. The first section covers basic topics, ranging from joints homeostasis and biomechanics, to genetics, bio-orthopedics, tissue engineering and 3D bioprinting. The following sections are each dedicated to a specific joint – its functional anatomy, pathologic conditions, diagnostics and treatment. This book is of interest to orthopedists and sports medicine specialists treating common and complex injuries of the joints.

Since the advent of cross-sectional imaging methods, few works have been devoted to pediatric musculoskeletal imaging, and information is especially limited on the skeletally immature joint. Furthermore, reduced emphasis on pediatric training means that general radiologists are increasingly unfamiliar with normal and abnormal imaging findings in children and adolescents. Knowledge of the imaging appearances of the immature joint is, however, crucial for correct image interpretation. This book covers key selected topics in the imaging evaluation of the skeletally immature joint. The opening chapters consider the current role, advantages, and limitations of each modality in pediatric assessment and present the imaging appearances of anatomic and developmental peculiarities of the growing skeleton. Findings in a wide range of important conditions are then described in a series of richly illustrated chapters that document appearances on diverse imaging studies, from conventional radiography through to modern high-tech modalities. By presenting the essential information on imaging of the immature joint, the authors hope to provide radiologists (musculoskeletal specialists and generalists alike) with a new tool that will assist greatly in overcoming the daily challenges posed by interpretation of pediatric examinations in the twenty-first century. The book will also be of interest to all other specialists involved in the diagnosis and treatment of children and adolescents with articular complaints.

This illustrated book assesses the role, advantages and limitations of each imaging modality from conventional to high-tech, showing anatomic and developmental peculiarities of the growing skeleton, and describing findings in a wide range of conditions.

This book offers a comprehensive overview of the basic science and clinical evidence for non-arthroplasty interventions in the adult knee. It aims to cover all aspects of joint-preserving knee surgery, from injectable therapies such as platelet-rich plasma and stem cell therapies to surgical interventions such as meniscal repair and replacement, ligament reconstructions, and osteotomies. Following discussion of clinical assessment and imaging, individual chapters focus on specific clinical problems, including patellofemoral joint disorders, chondral injuries, and bone tumors. For each condition, a thorough overview is provided, describing clinical assessment, management (including surgical and non-surgical methods), and novel therapies. The contributors are experts in their fields from across Europe and are drawn from the worlds of clinical and academic orthopedic surgery. This book is unique in its coverage of the entire span of non-arthroplasty knee surgery and its focus on both clinical and basic science aspects. It will be helpful for knee surgeons and those engaged in research on knee-related topics, but also for students and other physicians involved in the care of patients with disorders of the knee. .

Comprised of clinical cases demonstrating strategies for both common and complex knee preservation, this concise, practical casebook will provide orthopedic surgeons with the best real-world strategies to properly manage the many kinds of knee injuries and disorders they may encounter. The opening section presents the knee joint as a unique structure, reviewing the anatomy and function of articular cartilage and the meniscus, the effects of joint malalignment, the role of the synovium, and how joint failure is defined. The next two sections are comprised of clinical cases with a unique presentation, followed by a description of the diagnosis, assessment and management techniques used to treat it, as well as the case outcome, and clinical pearls and pitfalls. Cases included illustrate small and large cartilage defects, osteochondritis dessicans, chondral defects and lesions, meniscal allograft transplantation, and tibial and tibiofemoral cartilage defects, among others. The final section examines the current evidence for the treatment of articular cartilage lesions and emerging techniques in knee joint preservation and cartilage restoration. Pragmatic and reader-friendly, Joint Preservation of the Knee: A Clinical Casebook is an excellent resource for orthopedic surgeons and sports medicine specialists treating common and complex injuries of the knee.

"Joint Species Distribution Modelling (JSDM) is a fastdeveloping field and promises to revolutionise how data on ecological communities are analysed and interpreted. Written for both readers with a limited statistical background, and those with statistical expertise, this book provides a comprehensive account of JSDM. It enables readers to integrate data on species abundances, environmental covariates, species traits, phylogenetic relationships, and the spatio-temporal context in which the data have been acquired. Step-by-step coverage of the full technical detail of statistical methods is provided, as well as advice on interpreting results of statistical analyses in the broader context of modern community ecology theory. With the advantage of numerous example R-scripts, this is an ideal guide to help graduate students and researchers learn how to conduct and interpret statistical analyses in practice with the R package HMSC-R, providing a fast starting point for applying joint species distribution modelling to their own data"-- Provided by publisher.

This book provides clear instruction on the surgical treatment of joint problems in adult hemophilia patients. The procedures applicable to specific joints, including the shoulder, elbow, hip, knee, and ankle, are carefully reviewed with the aid of high-quality illustrations. The surgical treatment of articular hemophilic pseudotumors and bone cysts is also considered. In addition, clinically relevant information is provided on a range of topics, such as the treatment of hemophilic hemarthroses, the imaging of hemophilic joints, hematological perioperative management, anesthesia, rehabilitation, and pharmacoeconomics. Finally, the controversial issues of postoperative thromboembolic prophylaxis and the role of COX-2 inhibitors in hemophiliacs are reviewed. The guidance provided draws on both the authors? extensive personal experience and an in-depth review of the pertinent literature. The book offers an excellent, up-to-date account of knowledge on musculoskeletal problems and approaches to joint surgery in adults with hemophilia. It will be of value to orthopedic surgeons, rehabilitation physicians, hematologists, radiologists, and pharmacy researchers.

The challenge of health care delivery and health policy -- Organization of care -- The politics of health care in the United States -- Comparative health systems -- Population health -- Public health : a transformation for the 21st century -- Health and behavior -- Vulnerable populations : meeting the health needs of populations facing health inequalities -- The health workforce -- Health care financing -- Health care costs and value -- High-quality health care -- Health care management -- Health information technology -- The future of health care delivery and health policy.

"This is the ninth edition of An Introduction to the U.S. Health Care System, now titled Jonas' Introduction to the U.S. Health Care System. It was our privilege, and indeed it was an honor, to be asked by Dr. Steven Jonas to coauthor the sixth edition with him in preparation for assumption of full authorship of subsequent editions. The intended transition from Dr. Jonas to us came about, and we hope that this edition of the classic text about the health care system in the United States carries on the tradition of excellence begun more than 30 years ago by Dr. Milton Roemer and continued by Dr. Jonas"-- Provided by publisher.

"He first full biography of Jonas Salk offers a complete picture of the enigmatic figure, from his early years working on an influenza vaccine--for which he never fully got credit--to his seminal creation of the Polio vaccine, up through his later work to find a cure for AIDS"-- Provided by publisher.

Electrophysiologic investigation : technical aspects -- Electrophysiologic investigation : general concepts -- Sinus node function -- Atrioventricular conduction[RN4] -- Intraventricular conduction disturbances -- Miscellaneous phenomena related to atrioventricular conduction -- Ectopic rhythms and premature depolarizations -- Supraventricular tachycardias -- Atrial flutter and fibrillation -- Preexcitation syndromes -- Recurrent ventricular tachycardia -- Evaluation of antiarrhythmic agents -- Catheter and surgical ablation in the therapy of arrhythmias.

"The purpose of this book is to provide the budding electrophysiologist with an electrophysiologic approach to arrhythmias, which is predicated on the hypothesis that a better understanding of the mechanisms of arrhythmias will lead to more successful and rationally chosen therapy. As such, this book will stress the methodology required to define the mechanism and site of origin of arrhythmias so that safe and effective therapy can be chosen. The techniques suggested to address these issues and specific therapeutic interventions employed represent a personal view, one that is based on experience and, not infrequently, on intuition."-- Provided by publisher.

This book provides valuable insight into emerging trends in healthcare delivery; patient, family and caregiver engagement and the intersection of the two. It is unique in that it not only incorporates patients voice but provides context in the application of patients families and caregivers in healthcare transformation and the future of healthcare models. It is suited toward not only promoting empathy toward patients but also challenging the reader to learn and think about the future of healthcare and the value of patients voice in policy making and decisions about healthcare. It provides valuable information on quality improvement, consumer experience and emerging careers in this area with practical information and interventions. Nurses and other members of the care team play a critical role in the evolving models of care and must stay abreast of emerging trend to ensure that patients needs are met while contributing to meeting the quality and economic goals of the organizations and care settings in which they work. This book will help to ensure that they remain abreast of changing trends in quality improvement, quality measurement, cost, health information technology and patient and family engagement so that they are in a position to lead their teams and organizations. Direct accounts from patients, family and caregivers who want their "voices" heard are incorporated throughout the book.

1. The developmental theory of embodiment: discovering paths in the body, journeys of girls and women -- 2. Qualified freedom on borrowed territories: early childhood to age eight -- 3. Intense transitions: tweens (ages 9-12) -- 4. The practice of corseting: early adolescence (ages 13-14) -- 5. The "perfection" of corseting: late adolescence (ages 15-17) -- 6. Re-capturing qualified freedom: possibilities in adult women's journeys -- 7. Charting a different future: embodied possibilities -- Appendix 1. Demographic summaries of participants in the three interview studies.

The book introduces The Joyful Freedom Approach, as a strategy for recovery from fatigue. The integrated, holistic approach has scope for supporting individuals who have experienced energy depletion not just due to cancer and its treatments, but also in relation to other illnesses, conditions or distressing life events. The approach is aimed at helping people to discover what they can do to energise their lives following an event such as cancer that has left them lacking vitality, wellness or a sense of direction and clarity about how to live life fully. Research has culminated in identifying five attributes of energy restorative activities; these are represented by the Energy Restoration Framework. The attributes of Purposeful Expanding, Connecting/Belonging, Awe-inspiring and Nourishing act as headings for discussion, planning and integration into an individual's recovery and beyond. ... (continues)

The aim of this book is to analyze the scientific biography of Judah Folkman, one of the most important scientists of the last century. More 50 years ago, Folkman found a revolutionary new way to think about cancer. Blood supply, Folkman hypothesized, was the key to tumor growth. Without new blood vessels, tumors simply did not thrive. In 1971, Folkman published his theory of angiogenesis in the "New England Journal of Medicine". Angiogenesis, the formation and recruitment of new blood vessels, is necessary for tumor growth. Critics of the theory were silenced over time as Folkman and his colleagues reported the first purified angiogenic molecule, the first angiogenesis inhibitor and proposed the concept of angiogenic disease. The mechanism of angiogenesis is now a worldwide field of investigation. Over the years, Folkman and a growing team of researchers have isolated the proteins and unraveled the processes that regulate angiogenesis. Meanwhile, a new generation of angiogenesis research has emerged as well, widening the field into new areas of human disease and deepening it to examine the underlying biological processes responsible for those diseases.

"Over 84,000 black and brown lives are needlessly lost each year due to health disparities, the unfair, unjust, and avoidable differences between the quality and quantity of health care provided to Americans who are members of racial and ethnic minorities and care provided to whites. Health disparities have remained stubbornly entrenched in the American health care system--and in Just Medicine, Dayna Bowen Matthew finds that they principally arise from unconscious racial and ethnic biases held by physicians, institutional providers, and their patients. Implicit bias is the single most important determinant of health and health care disparities. Because we have missed this fact, the money we spend on training providers to become culturally competent, expanding wellness education programs and community health centers, and even expanding access to health insurance will have only a modest effect on reducing health disparities. [...] In this book, she unites medical, neuroscience, psychology, and sociology research on implicit bias and health disparities with her own expertise in civil rights and constitutional law. Just Medicine offers us a new, effective, and innovative plan to regulate implicit biases and eliminate the inequalities they cause, and to save the lives they endanger."--Publisher's description.

The founder of the Equal Justice Initiative in Montgomery, Alabama recounts his experiences as a lawyer working to assist those desperately in need, reflecting on his pursuit of the ideal of compassion in American justice.

Inequities and health disparities are the greatest and most pressing social issues of our time. This book explores public health practice through the critical lens of social and structural justice by examining our approach to health and what it means to be healthy, systemically and structurally. Through recent events, the raw reality of health disparities and inequities have been exposed. These events are earmarked by COVID-19's decimating and disparate impacts on Black and Brown populations during one of the greatest social movements of our time to end racism. Since this very public explosion of intersecting forms of oppression and inequitable suffrage, many have clamored to make sense of it, to reframe our narratives toward action, and re-envision what progress and change could look like. This text is positioned as a tool to help professionals dismantle old ways of thinking while reconstructing new ones that can be more responsive in meeting the realities of today. The author challenges the reader to think about public health more deeply and pragmatically as the space for reconciling solutions to these poignant health issues. This requires the exploration of an ideological shift in how we think of health, how we prepare healthcare providers outside of an antiquated sick care system, and how we prioritize the determinants of health across a re-imagined continuum of care. The scope of this book ranges from a historical and structural examination of our beliefs about health to perceiving a more just system of care where health is intentionally co-created toward this aim. It intentionally explores health along the lines of equity and through the broader lens of the social determinants of health to shed light on the opportunity in this moment that public health creates for health care. Justice in Health is a timely and important resource for healthcare professionals (pre- and post-licensure) and healthcare decision-makers. The book also appeals more widely to instructors, academics, researchers, and students across disciplines of nursing, medicine, public heath, sociology, and social work.

Part I History, Anatomy and Tumor Biology -- Historical Background -- Surgical Anatomy of the Skull Base -- Pathologic and Electron Microscopic Features -- Recent Concept of Etiology -- Part II Clinical and Radiological Diagnosis -- Clinical Presentation -- Juvenile Angiofibroma and the Eye -- Radiological Diagnosis -- Staging Systems and their Use -- Part III Management -- Pre- and Intraoperative Embolization -- Anesthesia and Management of Intraoperative Bleeding -- Endoscopic Surgery -- Endoscopic Excision of Advanced with Skull Base Involvement -- Excision by Midfacial Degloving Approach -- Excision by Modified Transpalatal and Maxillary Swing Approach Excision by Le Fort I Osteotomy Approach -- Excision by Lateral Skull Base Approach -- Combined Neurosurgical and Craniofacial Approach for Large Intracranial Tumor -- Radiation Therapy -- Adjuvant Chemotherapy and Hormonal Therapy -- Part IV Other Issues -- Recurrence of Tumor -- Its Prevention and Management -- Extranasopharyngeal Angiofibroma -- Remaining Controversies in Nasopharyngeal Angiofibroma.

Juvenile Nasopharyngeal Angiofibroma is a rare tumor in adolescent males. This book, the first of its kind devoted to the management of this tumor, is based on Dr N. Janakiram's paradigm shifting management technique for these highly vascular tumors. These tumors have always been a challenge for skull-base surgeons globally. Classical approaches for managing them comprised employing the endoscopic approach for small tumors and invasive approaches for large ones. Dr Janakiram's methodology employs the minimally invasive endoscopic approach for all stages of these tumors, except those which have massive intracranial extensions or have extensions into the parapharyngeal space which cannot be accessed by the endoscopic technique. In detailing the new approach, this volume also offers a new classification for different stages of these tumors and explains surgical techniques for managing them. This meets a long-standing requirement as the classification had remained incomplete because of the lack of adequate number of reported cases globally.