Books

V

  • Digital/Print
    edited by Pierre Ferrier.
    Digital : Springer2009
    Print2009
    Early steps of V(D)J rearrangement : insights from biochemical studies of RAG-RSS complexes / Patrick C. Swanson, Sushil Kumar, and Prafulla Raval -- Regulation of RAG transposition / Adam G.W. Matthews and Marjorie A. Oettinger -- Recent insights into the formation of RAG-induced chromosomal translocations / Vicky L. Brandt and David B. Roth -- V(D)J recombination deficiencies / Jean-Pierre de Villartay -- Large-scale chromatin remodeling at the immunoglobulin heavy chain locus : a paradigm for multigene regulation / Daniel J. Bolland, Andrew L. Wood, and Anne E. Corcoran -- Genetic and epigenetic control of V gene rearrangement frequency / Ann J. Feeney -- Dynamic aspects of TCRa gene recombination : qualitative and quantitative assessments of the TCRa chain repertoire in man and mouse / Evelyne Jouvin-Marche, Patrizia Fuschiotti, and Patrice Noël Marche -- Germline transcription : a key regulator of accessibility and recombination / Iratxe Abarrategui and Michael S. Krangel -- Dynamic regulation of antigen receptor gene assembly / Lance R. Thomas, Robin Milley Cobb, and Eugene M. Oltz -- Molecular genetics at the T-cell receptor b locus : insights into the regulation of V(D)J recombination / Marie Bonnet, Pierre Ferrier, and Salvatore Spicuglia -- Molecular pathways and mechanisms regulating the recombination of immunoglobulin genes during B-lymphocyte development / Kristen Johnson, Karen L. Reddy, and Harinder Singh -- Regulation of V(D)J recombinationby E-protein transcription factors / Mary Elizabeth Jones and Yuan Zhuang -- Temporal and spatial regulation of V(D)J recombination : interactions of extrinsic factors with the RAG complex / Yun Liu, Li Zhang, and Stephen Desiderio -- V(D)J recombination : of mice and sharks / Ellen Hsu -- Normal and pathological V(D)J recombination : contribution to the understanding of human lymphoid malignancies / Saïda Dadi ... [et al.].
  • Digital
    CDC2014
  • Print
    Lars Hangartner, Dennis R. Burton, editors.
    Vaccines against antigenically stable pathogens, or pathogens that only exist in a limited number of serotypes, have been very successful in the past and have drastically decreased the incidence and lethality of many diseases. However, when it comes to highly variable pathogens or viruses that exist in multiple serotypes, the traditional methods for vaccine development have reached their limits. This volume highlights the development of vaccines against such challenging pathogens. Novel approaches for immunogen design, including structure-guided vaccine development and vaccines targeting glycans, as well as adjuvants and animal models used for testing possible vaccine candidates are outlined and discussed in detail. Given its scope, the book will appeal to scientists in the fields of infectious diseases, microbiology and medicine.
  • Digital
    edited by Christopher B. Fox.
    Springer2017
  • Digital
    edited by Barry R. Bloom, Paul-Henri Lambert.
    ClinicalKey2016
  • Digital
    Pamela G. Rockwell, editor.
    Springer2017
  • Digital
    edited by Alejandro Brun.
    Springer2016
    Vaccines and vaccination for veterinary viral diseases : a general overview / Alejandro Brun -- Using IC-tagging methodology for production and purification of epitope-loaded protein microspheres for vaccination / Natalia Barreiro- Piñeiro ... [et al.] -- Plant-based vaccine antigen production / Hoang Trong Phan and Udo Conrad -- DNA vaccines : experiences in the swine model / Francesc Accensi, Fernando Rodríguez, and Paula L. Monteagudo -- Novel adjuvants and immunomodulators for veterinary vaccines / Peter M.H. Heegaard, Yongxiang Fang, and Gregers Jungersen -- Polymerase mechanism-based method of viral attenuation / Cheri A. Lee ... [et al.] -- BacMam platform for vaccine antigen delivery / Günther M. Keil ... [et al.] -- Laboratory-scale production of replication-deficient adenovirus vectored vaccines / Susan J. Morris ... [et al.] -- Generation of recombinant modified vaccinia virus ankara encoding VP2, NS1, and VP7 proteins of bluetongue virus / Alejandro Marín- López and Javier Ortego -- Generation of recombinant capripoxvirus vectors for vaccines and gene knockout function studies / Hani Boshra, Jingxin Cao, and Shawn Babiuk -- Recombinant swinepox virus for veterinary vaccine development / Hong-Jie Fan and Hui-Xing Lin -- Generation and selection of Orf virus (ORFV) recombinants / Hanns-Joachim Rziha, Jörg Rohde, and Ralf Amann -- Polycistronic herpesvirus amplicon vectors for veterinary vaccine development / Anita Felicitas Meier, Andrea Sara Laimbacher, and Mathias Ackermann -- Construction and application of newcastle disease virus-based vector vaccines / Paul J. Wichgers Schreur -- Chimeric pestivirus experimental vaccines / Ilona Reimann, Sandra Blome, and Martin Beer -- Analysis of the cellular immune responses to vaccines / Nicholas Svitek ... [et al.].
  • Digital
    Andrew W. Artenstein, editor.
    Springer2010
    Vaccinology in context : the historical burden of infectious diseases / Andrew W. Artenstein -- Smallpox / Andrew W. Artenstein -- A brief history of microbiology and immunology / Steven M. Opal -- Anthrax / Peter C.B. Turnbull -- Rabies / Hervé Bourhy, Annick Perrot, and Jean-Marc Cavaillon -- Killed vaccines : cholera, typhoid, and plague / Charles C.J. Carpenter and Richard B. Hornick -- Toxoid vaccines / John D. Grabenstein -- Tuberculosis and BCG / Marina Gheorghiu, Micheline Lagranderie, and Anne-Marie Balazuc -- The discovery of viruses and the evolution of vaccinology / Nicholas C. Artenstein and Andrew W. Artenstein -- Yellow fever / Thomas P. Monath -- Influenza / Andrew W. Artenstein -- Polio / David Oshinsky -- Measles, mumps, and rubella / Kathleen M. Gallagher ... [et al.] -- Diseases of military importance / Alan Cross and Phil Russell -- Varicella and zoster / Anne A. Gershon -- Polysaccharide vaccines / Andrew W. Artenstein -- Hepatitis B / Baruch S. Blumberg -- Japanese encephalitis / Scott B. Halstead -- Hepatitis A / Leonard N. Binn and Stanley M. Lemon -- Rotavirus / Penelope H. Dennehy -- Human papillomaviruses / Ian H. Frazer -- The future of vaccine discovery and development / Adel Mahmoud.
  • Digital
    edited by Joseph Domachowske, Manika Suryadevara.
    Springer2021
    Springer Nature eBook.
    This book is designed to provide easy-to-read and basic information about vaccines for those undertaking a vaccine course or for medical providers seeking to improve their skills. Written by expert medical educators in the areas of infectious diseases, medical microbiology, and pediatrics, this book begins by establishing the fundamentals of vaccines such as what constitutes a vaccine, how they are manufactured and composed, how they are tested for safety and efficacy, and how vaccine recommendations are developed and conveyed to health care providers and their patients. The book then explains the composition, safety profile, effectiveness, and current recommendations for use of every available vaccine, alphabetized by infection. The concluding section illuminates practical concerns every vaccinating clinician experiences, including vaccine confidence and hesitancy, misconceptions, and patient communication. Vaccines: A Clinical Overview and Practical Guide is an excellent learning tool for all students and providers administering vaccines to patients, including infectious disease specialists and other internal medicine subspecialists, pediatricians, geriatricians, as well as all other primary care physicians, nurse practitioners, physician's assistants, and nurses.
  • Digital
    Andrea Grignolio ; translated by Joan Rundo.
    Springer2018
    "The dangerous decline in vaccinations in many developed countries is at the heart of a lively debate that confirms how important the subject is today. Vaccinations are among mankind's most important scientific discoveries, yet they continue to be viewed with suspicion by part of the public - the victims of disinformation campaigns, instrumentalization and unfounded fears. There is, however, also an evolutionary explanation for these irrational beliefs, and countering the growing social opposition will be extremely difficult without grasping it. This book, which sheds new light on the safety and importance of vaccinations, is intended both for parents and those readers who want to understand the role of vaccinations in contemporary society, where the ease of access to knowledge is both a great opportunity and a great responsibility. The chapters follow a historical progression and conclude with a discussion of the most recent cognitive theories on how to overcome this opposition to vaccinations."--Back cover.
  • Digital/Print
    Rudolf Valenta, Robert L. Coffman, editors.
    Digital : Springer2011
    Print2011
    Immunological approaches for tolerance induction in allergy -- Clinical experience with recombinant molecules for allergy vaccination -- Allergen-specific immunotherapy with recombinant allergens -- Vaccine approaches for food allergy -- Intralymphatic immunotherapy: From the rationale to human applications -- Induction of allergen-specific tolerance via mucosal routes -- T cell epitope-based allergy vaccines -- Allergen-specific immunotherapy: Towards combination vaccines for allergic and infectious diseases -- Passive immunization with allergen-specific antibodies -- Cell-based therapy in allergy -- Current strategies for allergen-specific immunotherapy at its centenary.
  • Digital
    edited by Alan D.T. Barrett, Lawrence R. Stanberry.
    ScienceDirect2009
  • Digital
    edited by Markus Kalkum and Margarita Semis.
    Springer2017
    Mouse immunization with radioattenuated yeast cells of Paracoccidioides basiliensis / Estefânia Mara do Nascimento Martins and Antero Silva Ribeiro de Andrade -- Heat-killed yeast as a pan-fungal vaccine / Marife Martinez, Karl V. Clemons, and David A. Stevens -- Immunoinformatics as a tool for new antifungal vaccines / Rupanjali Chaudhuri and Srinivasan Ramachandran -- Rational design of T lymphocyte epitope-based vaccines against Coccidioides infection / Brady J. Hurtgen and Chiung-Yu Hung -- Identification of fungal T cell epitopes by mass spectrometry-based proteomics / Bernd Roschitzki and Salomé LeibundGut-Landmann -- Intranasal antifungal vaccination using DNA-transfected dendritic cells / Shanjana Awasthi -- DNAhsp65 vaccine as therapy against paracoccidioidomycosis / Alice M. Ribeiro, André C. Amaral, Maria Sueli S. Felipe, and Anamelia L. Bocca -- Idiotypic antifungal vaccination : immunoprotection by antiidiotypic antibiotic antibodies / Luciano Polonelli, Walter Magliani, and Stefania Conti -- Peptide vaccine against paracoccidioidomycosis / Carlos P. Taborda and Luiz R. Travassos -- Methodology for anti-cryptococcal vaccine development / Ashok K. Chaturvedi and Floyd L. Wormley Jr -- Beta-glucan particles as vaccine adjuvant carriers / Zeynep Mirza, Ernesto R. Soto, Fusun Dikengil, Stuart M. Levitz, and Gary R. Ostroff -- Th1-inducing agents in prophylaxis and therapy for paracoccidioidomycosis / Thiago Aparecido da Silva, Fabrício Freitas Fernandes, Taise Natali Landgraf, Ademílson Panunto-Castelo, and Maria Cristina Roque-Barreira -- Nanoparticle-based mycosis vaccine / Swaleha Zubair, Asim Azhar, Nazoora Khan, Ejaj Ahmad, Mohd Ajmal, and Mohammad Owais -- Yeast expressing Gp43 protein as a vaccine against Paracoccidioides brasiliensis infection / Aline Ferreira Oliveira and Paulo S. R. Coelho -- Vaccination with phage-displayed antigenic epitope / Yicun Wang and Li Wang -- Preparation of an oral vaccine by proteome analysis and molecular display technology / Seiji Shibasaki and Mitsuyoshi Ueda -- Precise and efficient in-frame integration of an exogenous GFP tag in Aspergillus fumigatus by a CRISPR system / Chi Zhang and Ling Lu -- Endpoint assessment in rabbit models of invasive pulmonary aspergillosis and mucormycosis / Vidmantas Petraitis, Ruta Petraitiene, William W. Hope, and Thomas J. Walsh -- CD4+ T cells mediate aspergillosis vaccine protection / Diana Diaz-Arevalo and Markus Kalkum -- T-cell-mediated cross-protective Immunity / Nina Khanna and Claudia Stuehler -- Assessment of post-vaccination phagocytic activation using Candida albicans killing assays / Wenqing Li and Yan Hu -- Immunization with antigen-pulsed dendritic cells against highly virulent Cryptococcus gattii infection : analysis of cytokine-producing T cells / Keigo Ueno, Makoto Urai, Shogo Takatsuka, Masahiro Abe, Yoshitsugu Miyazaki, and Yuki Kinjo -- Testing antifungal vaccines in an animal model of invasive candidiasis and in human mucosal candidiasis / Esther Segal.
  • Digital
    volume editor, Birgit Weinberger.
    Karger2020
    "This book summarizes age-related changes of the immune system and their impact on immune responses to vaccination, as well as other factors influencing vaccine-induced immune responses in old age. It gives an overview of vaccines which are currently available for older adults and of novel technologies and targets which hopefully will lead to more and improved vaccines for this vulnerable population"-- Provided by publisher.
  • Digital/Print
    Richard W. Compans, Walter A. Orenstein, editors.
    Digital : Springer2009
    Print2009
    Part I. Pandemic Influenza Overview -- Pandemic influenza as a current threat -- Antigenic cross-reactivity among H5N1 Viruses -- -- Part II. Current Approaches for Human and Avian Vaccine Production -- Seasonal influenza vaccines -- Generation and characterization of candidate vaccine viruses for pre-pandemic influenza vaccines -- Live attenuated vaccines for pandemic influenza -- Influenza vaccines for avian species -- Development and application of avian influenza vaccines in China -- -- Part III. Novel Vaccine Approaches -- Designing vaccines for pandemic influenza -- Attenuated influenza virus vaccines with modified NS1 proteins -- DNA Vaccines against Influenza viruses -- Recombinant proteins produced in insect cells -- Influenza neuraminidase as a vaccine antigen -- Recombinant vectors as influenza vaccines -- Influenza virus-like particles as pandemic vaccines -- Pandemic influenza vaccines -- Adjuvants for pandemic influenza vaccines -- -- Part IV. Novel Approaches of Vaccine Delivery -- Transcutaneous immunization with influenza vaccines -- Microneedle-based vaccines -- -- Part V. Vaccine Evaluation, Production and Distribution -- Animal models for evaluation of influenza vaccines -- Immunosenescence and influenza vaccine efficacy -- Vaccines for pandemic influenza: summary of recent clinical trials -- Considerations for licensure of influenza vaccines with pandemic and pre-pandemic indications -- Strategies for broad global access to pandemic influenza -- Prioritization of pandemic influenza vaccine: rationale and strategy for decision-making.
  • Digital
    edited by Stuart N. Isaacs.
    Springer2012
    Working safely with vaccinia virus : laboratory technique and review of published cases of accidental laboratory infections / Stuart N. Isaacs -- In-Fusion® cloning with vaccinia virus DNA polymerase / Chad R. Irwin, Andrew Farmer, David O. Willer, and David H. Evans -- Genetic manipulation of poxviruses using bacterial artificial chromosome recombineering / Matthew G. Cottingham -- Easy and efficient protocols for working with recombinant Vaccinia virus MVA / Melanie Kremer, Asisa Volz, Joost H.C.M. Kreijtz, Robert Fux, Michael H. Lehmann, and Gerd Sutter -- Isolation of recombinant MVA using F13L selection / Juana M. Sánchez-Puig, María M. Lorenzo, and Rafael Blasco -- Screening for vaccinia virus egress inhibitors : separation of IMV, IEV, and EEV / Chelsea M. Byrd and Dennis E. Hruby -- Imaging of vaccinia virus entry into HeLa cells / Cheng-Yen Huang and Wen Chang -- New method for the assessment of Molluscum contagiosum virus infectivity / Subuhi Sherwani, Niamh Blythe, Laura Farleigh, and Joachim J. Bugert -- An Intradermal model for vaccinia virus pathogenesis in mice / Leon C.W. Lin, Stewart A. Smith, and David C. Tscharke -- Measurements of vaccinia virus dissemination using whole body imaging : approaches for predicting of lethality in challenge models and testing of vaccines and antiviral treatments / Marina Zaitseva, Senta Kapnick, and Hana Golding -- Mousepox, a small animal model of smallpox / David Esteban, Scott Parker, Jill Schriewer, Hollyce Hartzler,and R. Mark Buller -- Analyzing CD8 T cells in mouse models of poxvirus infection / Inge E.A. Flesch, Yik Chun Wong, and David C. Tscharke -- Generation and characterization of monoclonal antibodies specific for vaccinia virus / Xiangzhi Meng and Yan Xiang -- Bioinformatics for analysis of poxvirus genomes / Melissa Da Silva and Chris Upton -- Antigen presentation assays to investigate uncharacterized immunoregulatory genes / Rachel L. Roper -- Characterization of poxvirus-encoded proteins that regulate innate immune signaling pathways / Florentina Rus, Kayla Morlock, Neal Silverman, Ngoc Pham, Girish J. Kotwal, and William L. Marshall -- Application of quartz crystal microbalance with dissipation monitoring technology for studying interactions of poxviral proteins with their ligands / Amod P. Kulkarni, Lauriston A. Kellaway, and Girish J. Kotwal -- Central nervous system distribution of the poxviral proteins after intranasal administration of proteins and titering of vaccinia virus in the brain after intracranial administration / Amod P. Kulkarni, Dhirendra Govender, Lauriston A. Kellaway, and Girish J. Kotwal
  • Digital
    Archana Chatterjee, editor.
    Springer2013
    The History of Vaccine Challenges: Conquering Diseases, Plagued by Controversy / Laura A. Jana -- Vaccine Development and Safety / Avinash K. Shetty -- Known Vaccine-Associated Adverse Events / B. A. Pahud -- Communicating Vaccine Risks and Benefits / Clea Sarnquist -- Vaccine Refusal: Perspectives from Pediatrics / Kody Moffatt, Clancy McNally -- The Anti-vaccine Movement: A Pharmacist's View / Jeffery Goad -- Antivaccinationism: Parental Viewpoint / Anna M. Johnson -- The Vaccine Misinformation Landscape in Family Medicine / Donald B. Middleton -- Vaccines: Boon or Bane--A Nurse's Outlook / Catherine O'Keefe -- The Controversy That Will Not Go Away: Vaccines and Autism / Archana Chatterjee, -- Thimerosal and Other Vaccine Additives / James H. Conway -- Perceived Risks from Live Viral Vaccines / Alice Pong, Mark Sawyer -- Can Vaccines Cause Cancer? / Ann-Christine Nyquist -- Autoimmunity, Allergies, and Asthma: A Relationship to Vaccines? / Harold C. Delasalas -- The Role of Public Health Ethics in Vaccine Decision Making: Insights from the Centers for Disease Control and Prevention / Leonard Ortmann -- Alternative Schedules: Why Not? / Michael J. Smith -- Influenza Vaccines and Guillain Barré Syndrome / Nandini Bakshi, James J. Sejvar -- Can Vaccines Cause Chronic Diseases? / Ann-Christine Nyquist -- Kawasaki Disease and Sudden Infant Death Syndrome: Any Connection to Vaccination? / Kari Neemann -- Political and Legal Issues in Vaccination / Linda K. Ohri -- The Media's Role in Vaccine Misinformation / Paola Dees -- Vaccines and the Internet / David M. Berman -- An International Perspective on Vaccine Safety / Rajib Dasgupta -- An Infection Prevention Perspective on Immunizations / Sharon Plummer -- Insights from Public Health: A Framework for Understanding and Fostering Vaccine Acceptance / Glen J. Nowak, Kate LaVail.
  • Digital
    Johannes Zschocke, Georg F. Hoffmann ; foreword by William L. Nyhan ; contributors, Alberto B. Burlina [and others].
  • Digital
    [edited by] Victor W. Nitti, Nirit Rosenblum, Benjamin M. Brucker ; illustrated by Joe Chovan.
    ClinicalKey2012
    How to perform a focused pelvic examination on a woman with pelvic floor dysfunction / Eva Fong, Mickey Karram and Victor W. Nitti -- Vaginal incisions and dissection / Victor W. Nitti and Benjamin M. Brucker -- Pelvic organ prolapse : introduction, nonsurgical management, and planning of surgical repair / Grace Y. Biggs, Victor W. Nitti, Mickey Karram -- Repair of anterior vaginal wall prolapse / Victor W. Nitti and Mickey Karram -- Indications and techniques for vaginal hysterectomy for uterine prolapse / Nirit Rosenblum Victor W. Nitti -- Vaginal Repair of enterocele and apical prolapse / Victor W. Nitti and Mickey Karram -- Repair of the posterior vaginal compartment / Nirit Rosenblum and Victor W. Nitti -- Repair of pelvic organ prolapse utilizing synthetic mesh kits / Janelle Evans and Mickey Karram -- Obliterative procedures for the correction of pelvic organ prolapse / Benjamin M. Brucker, Denise Chow and Victor W. Nitti -- Urethral diverticulectomy / Victor W. Nitti -- Benign vaginal wall masses and paraurethral lesions / Sagar R. Shah and Victor W. Nitti -- Female urethral reconstruction / Victor W. Nitti and Nirit Rosenblum -- Treatment of obstruction following stress incontinence surgery / Sagar R. Shah and Victor W. Nitti -- Vaginal repair of urethrovaginal and vesicovaginal fistulae / Nirit Rosenblum and Victor W. Nitti -- Avoiding and managing vaginal surgery complications-a series of case discussions / Mickey Karram.
  • Digital
    Basabdatta Sen Bhattacharya, Fahmida N. Chowdhury, editors.
    Springer2015
    1. Introduction -- 2. Discovery and validation of biomarkers based on computational models of normal and pathological hippocampal rhythms -- 3. DCM conductance based models and clinical applications -- 4. Computational models of closed-loop deep brain stimulation -- 5. A multiscale "working brain" model -- 6. How to render neural fields more realistic -- 7. Multilevel computational modelling in epilepsy: classical studies and recent advances -- 8. Computational modeling of neuronal dysfunction at molecular level validates the role of single neurons in circuit functions in cerebellum granular layer -- 9. Modelling cortical and thalamocortical synaptic loss and compensation mechanism in Alzheimer's disease -- 10. Toward networks from spikes -- 11. Epileptogenic networks: applying network analysis techniques to human seizure activity -- Index.
  • Digital
    by Naomi Feil and Vicki de Klerk-Rubin.
    ProQuest Ebook Central2012
    Validation is a practical way of communicating with and managing problem behavior in older adults with Alzheimer's-type dementia. It helps reduce stress, enhance dignity, and increase happiness. Caregivers who use these techniques validate older adults' expressed feelings, rather than focusing on disorientation and confusion.
  • Digital/Print
    Chantra Eskes, Maurice Whelan, editors.
    Digital : Springer2016
    Print2016
    Introduction / Chantra Eskes, Maurice Whelan -- Validation in support of internationally harmonised OECD test guidelines for assessing the safety of chemicals / Anne Gourmelon, Nathalie Delrue -- Regulatory acceptance of alternative methods in the development and approval of pharmaceuticals / Sonja Beken, Peter Kasper, Jan-Willem van der Laan -- Validation of alternative in vitro methods to animal testing: concepts, challenges, processes and tools / Claudius Griesinger, Bertrand Desprez, Sandra Coecke, Warren Casey, Valérie Zuang -- Practical aspects of designing and conducting validation studies involving multi-study trials / Sandra Coecke [and others] -- Validation of computational methods / Grace Patlewicz, Andrew P. Worth, Nicholas Ball -- Implementation of new test methods into practical testing / Rodger D. Curren, Albrecht Poth, Hans A. Raabe -- Pathway based toxicology and fit-for-purpose assays / Rebecca A. Clewell [and others] -- Evidence-based toxicology / Sebastian Hoffmann, Thomas Hartung, Martin Stephens -- Validation of transcriptomics-based in vitro methods / Raffaella Corvi, Mireia Vilardell, Jiri Aubrecht, Aldert Piersma -- Ensuring the quality of stem cell-derived in vitro models for toxicity testing -- Glyn N. Stacey, Sandra Coecke, Anna-Bal Price, Lyn Healy, Paul Jennings, Anja Wilmes& -- Validation of bioreactor and human-on-a-chip devices for chemical safety assessment -- Sofia P. Rebelo [and others] -- Integrated approaches to testing and assessment / Andrew P. Worth, Grace Patlewicz -- International harmonization and cooperation in the validation of alternative methods / João Barroso [and others] -- Evolving the principles and practice of validation for new alternative approaches to toxicity testing / Maurice Whelan, Chantra Eskes.
  • Digital
    Richard Matthew Wiard.
    More than 76 million Americans have hypertension, or high blood pressure, which can shorten life by 10 15 years if left untreated. Hypertension increases the risk of developing cardiovascular diseases (CVD) such as stroke, heart attack, congestive heart failure, or kidney failure that are often debilitating and impact quality of life. Prevention is the key to minimize CVD risk and increase longevity, but accurate prognosis of a future disease is difficult. Elevated blood pressure (BP) is generally the first sign of risk, but measuring pressure alone does not provide insight to where in the body problems may exist. Therefore, other screening tests are needed to more specifically isolate the underlying cause, which would improve the selection process of prescribing medications, or diet and exercise changes. And similar to BP measurements, such hypertensive screening tests may need to be performed at home to improve accuracy, since doctor's visits often trigger physiological responses that falsely elevate and lower BP. To address these concerns this work describes the design and validation of a home based noninvasive system (a bathroom scale) to measure aortic pulse wave velocity (PWV), to assess arterial stiffness, which is a clinical risk factor for certain CV diseases. The purpose of this work was four-fold: to develop a home monitoring device with simple user operation; to develop biomechanical theories as to why forces in the aortic arch can be sensed synchronously at the feet; clinically validate the biomechanical theory; and to demonstrate potential clinical utility of standing PWV measurements for trending and prognosis. The PWV scale is comprised of two different sensing technologies, ballistocardiography and photoplethysmography, which are embedded in the scale to measure pulse arrival times in the aortic arch and the foot--simply by standing on the scale. Using this system, PWV can be routinely determined in less than 30-seconds--significantly faster than commercial systems using trained operators. To validate this PWV system, a novel biomechanical theory was developed called Central Aortic Forces (CAF) to explain how the cardiovascular forces inside the body can be synchronously sensed outside the body. The computational models accurately predicted the amplitude of forces in the aortic arch (2-3 Newtons at rest), which were empirically confirmed in a clinical study; the empirical results agreed within 10% of the theory. To demonstrate trending abilities, a longitudinal PWV study was also performed over a four month duration, with results highly correlated to the applanation methods. Finally, an age study was conducted to characterize arterial aging, which matched well (p< 0.01) in slope and intercept major clinical trials published in the literature using applanation PWV (clinical gold standard). Examples are given on how such a system may improve prognosis to detect early vascular aging in young adults, otherwise masked in standard blood pressure measurements.
  • Digital
    Boris Bogdan, Ralph Villiger.
    Springer2008
  • Digital
    edited by Jennifer L. Wiler, Jesse M. Pines, Michael J. Ward.
    Cambridge2017
    1. Fifty years of transformation of acute and emergency care -- 2. Fragmentation in acute and emergency care causes, consequences, and solutions -- 3. Measuring and improving quality of care -- 4. Alternative payment models in acute, episodic care: moving from volume to value -- 5. Improving timeliness and access of acute and emergency care: the science of improving emergency department crowding -- 6. Bringing the patient voice into emergency care -- Case Study 1. Expanding the role of observation care -- Case study 2. An innovative strategy to streamline care for behavioral health in the emergency department -- Case study 3. The geriatric emergency department -- Case study 4. How the United Kingdom responded to the 4-hour rule -- Case study 5. High-cost users: using information technology to streamline care plans -- Case study 6. Emergency care in an integrated healthcare delivery system: the Kaiser experience -- Case study 7. Urgent care centers: an alternative to unscheduled primary care and emergency department care -- Case study 8. The "no-wait" emergency department -- Case study 9. Transforming care delivery through telemedicine -- Case study 10. Coordinating emergency care through telemedicine -- Case study 11. Bringing diagnostic testing to the bedside: point of care testing -- Case study 12. Regionalization of care -- Case study 13. Clinical decision support tools -- Case study 14. Automated patient follow-up program -- Case study 15. Using data on patient experience to improve clinical care -- Case study 16. Community paramedicine: the Geisinger experience -- Case study 17. Initiating palliative care in the emergency department -- Case study 18. Streamlining patient flow in the emergency department with discrete event simulation -- Case study 19. Using emergency department community health workers as a bridge to ongoing care for frequent ED users -- Case study 20. Big data: use of analytics for operations management.
  • Digital
    Rajiv K. Sethi, Anna K. Wright, Michael G. Vitale, editors.
    Springer2020
    Intro -- Preface -- Contents -- Contributors -- 1: Macro Trends in Healthcare Delivery -- The Spiraling Cost of Healthcare -- Models of Value-Based Reimbursement -- Accountable Care Organization (ACO) -- Bundled Payment of Care Improvement (BPCI) -- Patient-Centered Medical Home (PCMH) -- Summary of VBR Models -- Other Macroeconomic Trends -- Price Controls and Decreases in Reimbursement -- Consolidation -- New Technology -- Telehealth -- Smart Pharmaceuticals and Devices -- Genetics -- Wearable Devices -- Big Data and Artificial Intelligence -- Conclusion: Finding Signal in the Noise 3: The Bree Collaborative Bundle for Lumbar Fusion: Evolution of a Community Standard for Quality -- Identifying and Managing Uncomplicated Back Pain: The Spine Clinic -- Engagement with Employers and the Marketplace Collaborative Model -- Redesigning the Care Pathway for Uncomplicated Back Pain -- Improved Quality and Timeliness of Care for Uncomplicated Back Pain -- Financial Consequences for Providers -- Lessons Learned from Starbucks, the Marketplace Collaborative, and Spine Clinic -- Replicating the Spine Clinic Model -- Lessons Learned from Intel's Collaborative and the Spine Clinic Beyond Spine Clinic: Contributions from Spine Surgery and Orthopedics -- The Robert Bree Collaborative: Putting It All Together -- Bree Collaborative Work Group on Lumbar Fusion -- The Evidence Table -- Cycle One: Standards for Appropriateness for Lumbar Fusion -- Cycle Two: Fitness for Surgery -- Cycle Three: Best Practice Surgery -- Cycle Four: Rapid Return to Function -- The Multidisciplinary Conference -- The Personal Care Partner -- Quality Measures -- The Warranty Against Avoidable Remissions -- Response of Health-Care Stakeholders to Surgical Bundles -- Employers -- Health Plans Providers -- Summary -- References -- 4: Multidisciplinary Evaluation Improves the Value of Lumbar Spine Care -- Multidisciplinary Conferences -- Multidisciplinary Clinics -- Discussion -- Conclusions -- References -- 5: Using Lean Process Improvement to Enhance Safety and Value -- What Is Standard Work? -- The Toyota Production System and Its Application in Healthcare -- What Is the Virginia Mason Production System? How Does This System Root Out Variability? -- Cultural Aspects of Hierarchy in Medicine and Surgery (the Old Standard Way)
  • Digital
    Carlos Francisco Silva, Oyunbileg von Stackelberg, Hans-Ulrich Kauczor, editors.
    Springer2020
    This cutting-edge guide to value-based radiology provides readers with the latest information on all aspects of the subject. Healthcare delivery is experiencing a rapid transition towards a value-based model, the underlying idea being that providers are paid on the basis of patient's health outcomes rather than the total services delivered. Radiology departments are facing many challenges as they attempt to improve operational efficiency, performance, and quality in order to keep pace with this transition. In the first part of this book, readers will find information on the theoretical basis and general concepts of value-based radiology. The second part focuses on value-based practice in specific areas of radiology: neuro/head and neck, thoracic, abdominopelvic, musculoskeletal, breast, cardiovascular, and pediatric. All topics are discussed by prominent experts in a clearly organized and well-illustrated form that will help readers to gain the most from each chapter. The book will be a valuable resource for radiologists and healthcare managers working in public or private institutions, as well as an excellent quick reference guide for all other physicians interested in the topic.
  • Digital
    James S. Powers.
    Springer2018
    This book traces the origins of value-based purchasing and current geriatric care models to deliver value in the broader healthcare system. The text focuses on the three goals that are expected to remain at the center of healthcare: improving access to healthcare via insurance coverage, improving the patient's experience and quality of care, and effectively managing healthcare costs. Chapters cover the quality indicators of care, drivers for improved outcomes, and models of care as seen in geriatrics as they can be expanded upon for the larger system. The text also discusses some of the most critical periods for aging patients and the ways that these lessons can inform the larger system. These topics include transitioning from the hospital to the home setting, collaborative care between geriatric workers, and staff training and the clinical needs for all changing demographics. As the healthcare system evolves and the population ages, Value Driven Healthcare and Geriatric Medicine proves to be a vital resource for geriatricians, primary care physicians, specialists who work with aging patients, hospital administrators, healthcare educators, healthcare organizations, and all medical professionals working with aging patients and patients affected by healthcare reform.
  • Digital
    [edited by] Denise L. Faustman.
    ScienceDirect2014
  • Digital
    edited by Denise L. Faustman.
    ScienceDirect2018
    Chapter 1. BCG: its impact on tuberculosis and relevance to autoimmune disease -- Chapter 2. The potential of TNF induction from BCG for the treatment of Type 1 Diabetes -- Chapter 3. Bacille Calmette-Guerin (BCG) vaccine in neuroinflammation -- Chapter 4. Host epigenetic modifications in Mycobacterium tuberculosis infection: a boon or bane -- Chapter 5. Mycobacterium Bovis Bacille Calmette-Guerin vaccination: can biomarkers predict efficacy? -- Chapter 6. The heterologous effects of Bacillus Calmette-Guerin (BCG) vaccine and trained innate immunity -- Chapter 7. Nonspecific effects of neonatal Bacille Calmette-Guerin (BCG) vaccination-- from West African observations to a Danish randomized clinical trial -- Chapter 8. Epigenetic rewiring of monocytes in BCG vaccination -- Chapter 9. Mycobacteria, immunoregulation, and autoimmunity -- Chapter 10. mTORC1 links cellular metabolism and immune functions in Mycobacterium tuberculosis infection and BCG vaccination -- Chapter 11. The role of maternal priming and boosting for the nonspecific effects of BCG vaccine -- Index.
  • Print
    Perry Nichols & co-workers.
  • Digital
    Joachim P. Sturmberg, editor.
    Springer2016
    Part I. The foundations of systems and complexity medicine -- 1. Heath and disease as emergent processes -- 2. The technological advances behind systems medicine -- 3. Individualized care -- today and tomorrow -- Part II. The complexity of common diseases -- 4. Multi-organ physiology -- 5. Infectious diseases -- 6. Cancer -- 7. Heart disease, diabetes and obesity -- 8. Neurodegenerative diseases -- 9. Multi-morbidity -- Part III. Ethics and Education -- the Challenges for Systems-based Medicine -- 10. Learning to cope in a complex adaptive environment -- 11. Regulatory and legal challenges -- 12. Ethical implication of systems medicine -- Part IV. Change in an Adaptive Organization -- 13. The dynamics of change -- 14. Flexible interdisciplinary teams -- 15. Health care -- a whole of society perspective.
  • Digital
    Christopher Heginbotham.
    Cambridge2012
    Provides a skills base and support processes for working with differences in values held by those engaged in commissioning decisions.
  • Digital
    Jill E. Thistlethwaite.
    Cambridge2012
    Values-based practice in health care : setting the scene -- Teamwork and collaborative practice in modern health care -- Communication within teams and between professionals -- A patient complaint : team meetings, policy, and practice values : raising awareness in the team -- A well person health check, health promotion, and disease prevention : different lifestyles, different values -- A patient with medically unexplained symptoms : applying evidence and values -- A request for strong analgesia : honesty and truth -- Asylum seekers and refugees : working across cultures -- A request for a home birth and other pregnancy related consultations -- Community based care and the wider health care team / Dawn Forman -- Ageing and end of life decisions -- Referrals and the interface between primary and secondary care: looking after "our" patients -- Living with visible difference and valuing appearance -- Collaboration with other professionals : in and outside health care -- Learning in and about teams.
  • Digital/Print
    edited by John Cameron, Paul Hunter, Paul Jagals and Katherine Pond.
    Digital : WHO2011
    Print2011
    "This publication addresses the broader issues of social cost-benefit analysis performed on options to invest in drinking-water supplies, with a focus on small community suppliers"--Back cover.
  • Digital
    Blase A. Carabello, editor.
    Springer2020
    A vital text for every aspiring and practicing clinician in relevant fields, this user-friendly guide to valvular heart disease includes diagnostic tables, guidance on the treatment of a range of conditions, and access to a range of additional video material.
  • Digital
    editors, Catherine M. Otto, Robert O. Bonow.
    ClinicalKey2021
    Front Cover -- Inside front cover -- Front Matter -- Valvular Heart Disease A Companion to Braunwald's Heart Disease FIFTH EDITION -- Copyright -- Contributors -- Foreword -- Preface -- Acknowledgments -- Braunwald's heart disease family of books -- Table of Contents -- 1 Epidemiology of valvular heart disease -- Key points -- Incidence and prevalence of valve disease -- Valve disease in industrially underdeveloped areas -- Incidence of rheumatic fever and chronic rheumatic disease -- Prevalence of rheumatic disease -- Valve disease in industrially developed areas -- Causes of valve disease Rheumatic fever -- Endomyocardial fibrosis -- Calcific aortic stenosis -- Mitral prolapse -- Secondary mitral regurgitation -- Secondary aortic regurgitation resulting from aortic dilation -- Secondary tricuspid regurgitation -- Infective endocarditis -- Replacement heart valves -- Congenital conditions -- Systemic inflammatory conditions -- Carcinoid, drugs, and radiation -- Carcinoid -- Drugs -- Radiation -- Disease by valve type -- Aortic stenosis and regurgitation -- Mitral stenosis -- Mitral regurgitation -- Right-sided valve disease -- Tricuspid valve disease -- Pulmonary valve disease Multiple valve disease -- Conclusions -- References -- 2 Three-dimensional anatomy of the aortic and mitral valves -- Key points -- Mitral valve -- Mitral valve anatomy -- Mitral valve annulus -- Mitral valve leaflets -- Mitral valve commissures -- Mitral valve chordae -- Papillary muscles -- 3DE and mitral valve apparatus -- 3DE imaging -- Image acquisition -- Image display -- 3DE mechanisms of mitral valve dysfunction -- Degenerative mitral valve disease -- Ischemic mitral regurgitation -- Mitral leaflet tethering in ischemic mitral regurgitation. Mitral valve annulus in ischemic mitral regurgitation. -- Leaflet growth in ischemic mitral regurgitation. -- Treatment of ischemic mitral regurgitation. -- 3DE quantification of mitral regurgitation -- 3D vena contracta area -- 3D proximal isovelocity surface area -- 3D anatomic regurgitant orifice area -- 3D mitral inflow and left ventricular outflow tract stroke volume -- Limitations of 3D-derived quantitative measurements for mitral regurgitation -- Mitral stenosis -- Aortic valve -- Aortic valve anatomy -- Aortic valve cusps -- Aortic valve annulus -- Aortic root complex Aortic valve physiology -- 3DE imaging -- Image acquisition -- Image display -- Roles for 3DE -- Aortic valve anatomy -- Native valves. -- Prosthetic valves. -- Endocarditis. -- Aortic stenosis assessment -- Left ventricular outflow tract. -- Stroke volume quantification. -- Aortic valve planimetry. -- Transcatheter aortic valve replacement -- Preprocedure: Aortic root assessment. -- Periprocedure. -- Postprocedure. -- Aortic regurgitation assessment -- Classification. -- Vena contracta. -- Stroke volume. -- Aortic-mitral valve interactions -- Conclusions -- References
  • Digital
    Michael Y. Henein, editor.
    Springer2009
    The Mitral Valve Disease / Michael Henein and John Pepper -- Aortic Valve Disease / Michael Henein and Joseph Maalouf -- Right Heart Valve Disease / Michael Henein -- Pulmonary Valve Disease / Michael Henein and Wei Li -- Stress Echo in Valvular Heart Disease / Eugenio Picano -- Valve Substitutes / John Chambers -- Native and Prosthetic Valve Endocarditis / Maurizio Galderisim and Sergio Mondillo.
  • Digital
    Douglas C. Eaton, John P. Pooler.
    AccessMedicine2013
    Renal functions, basic processes and anatomy -- Renal blood flow and glomerular filtration -- Clearance -- Basic transport mechanisms -- Renal handling of organic substances -- Basic renal processes for sodium, chloride, and water -- Regulation of sodium and water excretion -- Regulation of potassium balance -- Regulation of acid-base balance -- Regulation of calcium, magnesium and phosphate.
  • Digital
    Douglas C. Eaton, John P. Pooler.
    AccessMedicine2018
    Renal functions, basic processes, and anatomy -- Renal blood flow and glomerular filtration -- Clearance and measures of renal function -- Basic transport mechanisms -- Renal handling of organic solutes -- Basic renal processes for sodium, chloride, and water -- Regulation of sodium and water excretion -- Regulation of potassium balance -- Regulation of acid-base balance -- Regulation of calcium, magnesium, and phosphate.
  • Digital/Print
    Brit Bennett.
    Digital : EBSCO2020Limited to 3 simultaneous users
    Digital : ProQuest Ebook Central2020Limited to 1 simultaneous user
    Print2020
    "The Vignes twin sisters will always be identical. But after growing up together in a small, southern black community and running away at age sixteen, it's not just the shape of their daily lives that is different as adults, it's everything: their families, their communities, their racial identities. Ten years later, one sister lives with her black daughter in the same southern town she once tried to escape. The other secretly passes for white, and her white husband knows nothing of her past. Still, even separated by so many miles and just as many lies, the fates of the twins remain intertwined. What will happen to the next generation, when their own daughters' storylines intersect? Weaving together multiple strands and generations of this family, from the Deep South to California, from the 1950s to the 1990s, Brit Bennett produces a story that is at once a riveting, emotional family story and a brilliant exploration of the American history of passing. Looking well beyond issues of race, The Vanishing Half considers the lasting influence of the past as it shapes a person's decisions, desires, and expectations, and explores some of the multiple reasons and realms in which people sometimes feel pulled to live as something other than their origins. As with her New York Times-bestselling debut The Mothers, Brit Bennett offers an engrossing page-turner about family and relationships that is immersive and provocative, compassionate and wise"-- Provided by publisher.
  • Digital
    Committee on Geographic Variation in Health Care Spending and Promotion of High-Value Health Care, Board on Health Care Services ; Joseph P. Newhouse, Alan M Garber, Robin P. Graham, Margaret A. McCoy, Michelle Mancher, and Ashna Kibria, editors ; Institute of Medicine of the National Academies.
    NAP2013
    "Variation in Health Care Spending investigates geographic variation in health care spending and quality for Medicare beneficiaries as well as other populations, and analyzes Medicare payment policies that could encourage high-value care. This report concludes that regional differences in Medicare and commercial health care spending and use are real and persist over time. Furthermore, there is much variation within geographic areas, no matter how broadly or narrowly these areas are defined. The report recommends against adoption of a geographically based value index for Medicare payments, because the majority of health care decisions are made at the provider or health care organization level, not by geographic units. Rather, to promote high value services from all providers, Medicare and Medicaid Services should continue to test payment reforms that offer incentives to providers to share clinical data, coordinate patient care, and assume some financial risk for the care of their patients."--Publisher's description.
  • Digital
    NCBI Bookshelf2017
  • Digital
    edited by Xiaozhong Guo, Xingshun Qi.
    Springer2021
    Springer Nature eBook.
    This book discusses the management of variceal bleeding in liver cirrhosis, covering a wide range of topics, including epidemiology, mechanism, diagnosis and monitoring, prophylaxis, treatment, and prognostic assessment. It also presents the latest research in the field, such as non-invasive approaches, self-expanding metal stents, hemostatic powder, and early TIPS. The book is a valuable resource for physicians wanting to establish standard treatment strategies, researchers launching innovative clinical and experimental studies, and also for patients and their relatives wishing to gain a better understanding of this disease.
  • Digital
    Roberto de Franchis, Alessandra Dell'Era, editors.
    Springer2014
  • Digital/Print
    Allison Abendroth, Ann M. Arvin, Jennifer F. Moffat, editors.
    Digital : Springer2010
    Print2010
    The Varicella-zoster virus genome -- VZV molecular epidemiology -- Roles of cellular transcription factors in VZV replication -- Effects of Varicella-zoster virus on cell cycle regulatory pathways -- Varicella-zoster virus open reading frame 66 protein kinase and its relationship to alphaherpesvirus US3 kinases -- VZV ORF 47 serine protein kinase and its viral substrates -- Overview of Varicella-zoster virus glycoproteins gC, gH and gL -- Analysis of the function of glycoproteins E and I and their promoters during VZV replication in virto and in skin and T cell xenografts in the SCID mouse model of VZV pathogenesis -- Varicella-zoster virus glycoprotein M -- Varicella zoster virus immune evasion strategies -- VZV Infection of keratinocytes: production of cell-free infectious virions in vivo -- Varicella-zoster virus T cell tropism and the pathogenesis of skin infection -- Experimental models to study varicella zoster virus infection of neurons -- Molecular characterization of Varicella zoster virus (VZV) in latently infected human ganglia: physical state and abundance of VZV DNA, quantitation of viral transcripts and detection of VZV-specific proteins -- Neurological disease produced by Varicella zoster virus reactivation without rash -- Varicella-zoster virus neurotropism in SCID mouse-human DRG xenografts -- Rodent models of Varicella-zoster virus neurotropism -- Simian Varicella virus: molecular virology -- Simian Varicella virus pathogenesis -- Varicella-zoster virus vaccine : molecular genetics -- VZV T-cell-mediated immunity -- Perspectives on vaccines against Varicella-zoster virus infections.
  • Digital
    edited by Ann M. Arvin, Anne A. Gershon.
    Cambridge2010
  • Digital
    Helena M. Tabery.
    Springer2011
    Herpes zoster ophthalmicus (HZO) is a common disease in the elderly and the immunosuppressed, with potentially devastating sequelae. Diagnosis of HZO is clinical but almost all its manifestations are non-specific and often indistinguishable from those due to other causes in general and herpes simplex virus in particular. The exception is varicella-zoster virus epithelial keratitis, which is frequently the only indicator of the true nature of the disease. This book is unique in presenting high-magnification images, obtained by non-contact in vivo photomicrography, that capture the distinctive features of varicella-zoster virus epithelial keratitis in HZO. Both the morphology and the dynamics of the corneal epithelial lesions are splendidly documented, including in patients with HZO sine herpete and recurrent disease. Three rare cases of ocular surface involvement in acute HZO are included, and the final chapter offers an illuminating comparison of varicella-zoster virus epithelial keratitis in HZO and the lesions of herpes simplex virus. This book will serve as an indispensable aid in the prompt diagnosis of HZO.
  • Digital
    Sandro C. Esteves, Chak-Lam Cho, Ahmad Majzoub, Ashok Agarwal, editors.
    Springer2019
    This unique textbook - the first of its kind - presents a thoughtful and comprehensive discussion of the significance of varicocele and its impact on male fertility. This hot topic is covered from a multitude of angles in seven thematic sections: origin and pathophysiology, clinical evaluation, medical and surgical therapy, controversies, pro and con debates, and clinical case scenarios. The scope of varicocele includes basic and transitional research, genetics, diagnostic testing with conventional and advanced molecular biology approaches, hormonal control, interventional therapy and assisted reproductive technology (ART). Repair of varicocele, which can be carried out by various methods, not only alleviates oxidative stress-associated infertility but also prevents and protects against the progressive character of varicocele and its consequent upregulations of systemic oxidative stress. Even with the advances in the understanding of this intriguing disease and consensus on some areas such as diagnosis and pathophysiology, substantial controversy still exists, in particular concerning the benefits of treatment and to whom treatment should be offered. Additional chapters discuss, in depth, such controversies surrounding the role of varicocele in male infertility and present clinical case scenarios dealing with management of subclinical and clinical varicocele. A series of editorial comments is provided by the editors at the end of selected chapters, containing an objective and concise summary of the information from each chapter. In addition, chapters open up with key points for quick references and conclude with multiple choice questions and answers for immediate review and retention of the rich content. Generously illustrated, Varicocele and Male Infertility: A Complete Guide represents an invaluable tool for medical students in reproductive medicine as well as researchers and clinicians working in the field of infertility (e.g., urologists, gynecologists, re productive endocrinologists, and embryologists) and is comprised of chapters written by leading and internationally recognized clinicians and scientists with expertise in varicocele, skillfully edited by leaders in the field.
  • Digital
    [edited by] Felipe B. Collares, Salomão Faintuch.
    Thieme MedOne Radiology2017
    Anatomy / Felipe B. Collares -- Pathophysiology of varicose veins / Amy R. Deipolyi and Gloria M. Martinez Salazar -- Clinical exam / Michael G. Johnson, Jr., Igor Rafael Sincos, and Felipe B. Collares -- Imaging / Cyrillo R. Araujo, Jr. and Felipe B. Collares -- Compression therapy / Erica A. Gupta, Raphael J. Yoo, Carlos Alberto M. Carvalho, and Felipe B. Collares -- Endovenous thermal ablation / Amy R. Deipolyi, Gloria M. Martinez Salazar, Felipe B. Collares -- Sclerotherapy / Ian M. Brennan -- Ambulatory phlebectomy / Indravadan J. Patel and Suvranu Ganguli -- Safety, quality, and complications / Ann L. Brown, Lauren Ferrara, and Felipe B. Collares -- New endovascular techniques / Edward H. Ahn and Felipe B. Collares.
  • Digital
    edited by Ian Loftus, Robert J Hinchcliffe.
    ClinicalKey2019
    "Vascular and Endovascular Surgery meets the needs of surgeons in higher training and practising consultants for a contemporary and evidence-based account of this sub-specialty that is relevant to their general surgical practice. It is a practical reference source incorporating the most current information on recent developments, management issues and operative procedures. The text is thoroughly referenced and supported by evidence-based recommendations wherever possible, distinguishing between strong evidence to support a conclusion, and evidence suggesting that a recommendation can be reached on the balance of probabilities"--Publisher's description.
  • Digital
    John A. Kaufman, Michael J. Lee.
    ClinicalKey2014
    Vascular Pathology -- Fundamentals of Angiography -- Noninvasive Vascular Imaging -- Vascular Interventions -- Carotid and Vertebral Arteries -- Upper Extremity Arteries -- Upper Extremity, Neck, and Central Thoracic Veins -- Pulmonary Circulation -- Thoracic Aorta -- Abdominal Aorta and Pelvic Arteries -- Visceral Arteries -- Renal Arteries -- Inferior Vena Cava and Tributaries -- Portal and Hepatic Veins -- Lower-Extremity Arteries -- Lower-Extremity Veins -- Image-Guided Percutaneous Biopsy -- Percutaneous Abscess and Fluid Drainage -- Gastrointestinal Tract Intervention -- Biliary Intervention -- Gallbladder Intervention -- Percutaneous Genitourinary Intervention -- Image-Guided Breast Intervention -- Musculoskeletal Intervention -- Image-Guided Tumor Ablation: Basic Principles -- Image-Guided Ablation of Renal Tumors -- Image-Guided Ablation as a Treatment Option for Thoracic Malignancies -- Image-Guided Ablation of Liver Tumors.
  • Digital/Print
    editors, Brian Strife, Jeff Elbich.
    Digital : Ovid2020
    Print2020
    "The first ABR core examination was administered in October 2013 to third year radiology residents. This core examination, which is one component toward obtaining board certification in diagnostic radiology, tests knowledge and comprehension in 18 categories, all of which must be passed. The categories are: breast, cardiac, gastrointestinal, interventional, musculoskeletal, neuroradiology, nuclear, pediatrics, reproductive/endocrinology, thoracic, urinary, vascular, computed tomography, magnetic resonance, radiography/fluoroscopy, ultrasound, physics, and safety. The core exam will have approximately 660 questions and consist of approximately 60 questions from each category (except physics will have 110 questions). The exam is to be an "image-rich", computer-based exam with multiple-choice, extended answer, and blocked return type questions. The Core Review Series will be the first and only reference specifically designed for this new exam. Each title will consist of approximately 300 questions, in a format similar to the exam with image-rich MCQs. Answers to the questions will be discussed in a concise manner along with explanations of each choice followed by relevant references. Vascular and Interventional Radiology: A Core Review will include high quality angiographic, fluoroscopic, CT, MRI, and ultrasound images that demonstrate the broad range of clinical entities encountered in the field. Answers to the questions will be discussed in a concise manner with brief discussion of the clinical pearls and rationale behind the correct answer. Literature references will be provided for each question so the reader will know where to go for further reading on the subject"--Provided by publisher.
  • Digital
    edited by Cameron C. Trenor III, Denise M. Adams.
    Springer2020
    This volume is a practical resource for the diagnosis and multi-disciplinary management of patients with vascular anomalies. Although designed by and for hematologists and oncologists, this text also assists clinicians in many specialties with appropriate nomenclature, diagnosis, and management of the heterogeneous disorders considered as vascular anomalies, including kaposiform hemangioendothelioma, capillary malformations, venous malformations, lymphatic anomalies, and arteriovenous malformation. The book features full-color clinical photographs and diagnostic imaging to enrich descriptions of these conditions and to ensure accurate diagnosis for appropriate management recommendations. Written by experts in their fields, Vascular Anomalies: A Guide for the Hematologist/Oncologistis a valuable resource for clinicians treating and researchers studying patients with vascular anomalies.
  • Digital
    Arin K. Greene.
    Thieme MedOne Plastic Surgery2013
    Vascular anomalies are common lesions affecting at least five percent of the population. Patients often require multidisciplinary care and are familiar to most medical and surgical specialties. Vascular Anomalies: Classification, Diagnosis, and Management is a clinically oriented manual that can be used for patient care, teaching, or research. The book covers the entire field of vascular anomalies, including infantile hemangioma, congenital hemangioma, kaposiform hemangioma, pyogenic granuloma, rare vascular tumors, capillary malformation, venous malformation, lymphatic malformation, lymphedema, and arteriovenous malformations, as well as overgrowth syndromes.
  • Print
    Yuping Wang.
    The placenta is an organ that connects the developing fetus to the uterine wall, thereby allowing nutrient uptake, waste elimination, and gas exchange via the mother's blood supply. Proper vascular development in the placenta is fundamental to ensuring a healthy fetus and successful pregnancy. This book provides an up-to-date summary and synthesis of knowledge regarding placental vascular biology and discusses the relevance of this vascular bed to the functions of the human placenta.
  • Digital
    David Abraham ... [et al.] (eds.).
    Springer2008
  • Digital
    by Robert Pelberg, Wojciech Mazur.
    Springer2011
    CT basics -- Concepts in radiation -- Technical aspects of vascular CT angiography -- Carotid and upper extremity CT angiography -- Thoracic aortic CT angiography -- Abdominal aortic CT angiography -- Peripheral arterial CT angiography.
  • Digital
    Michael G. Hennerici, Doris Neuerburg-Heusler ; with contributions by Michael Daffertshofer, Thomas Karasch, Stephen Meairs.
    Thieme MedOne Radiology2005
    v. 1. Cerebral and peripheral vessels.
  • Digital
    Roni Aloni.
    Springer2021
    The book is intended as a guide for molecular biology students, equipping them to successfully study plants. It pursues a holistic approach, viewing the whole plant as an integrated operating organism, and is written in a straightforward manner, making it appealing to anyone interested in plants. Further, it reflects the latest findings for scientists and students in the fields of plant sciences, biology, agriculture, forestry, ecology, vascular medicine and cancer, discussing e.g. how hormonal signals induce and regulate simple and complex patterns in plants vascular tissues, their adaptation and evolution; written by a world-renowned expert who has worked in the field for 50 years; covers the field from the initial studies conducted more than a century ago up to recent studies with up-to-date explanations; describes in details the structure, development, physiology and basic molecular biology of plants' vascular tissues, their function, regeneration and environmental adaptation; explores the controlling mechanisms of plant vascular differentiation by continuously moving hormonal signals and their precursors; discusses the regulation of stem cells and cambium, control of gradients in vascular cell size along the plant, juvenile-adult transition and rejuvenation, grafting, mechanisms of recovery from bending by reaction wood, evolution of vessels and fibers from tracheids, regulation of ring-porous wood evolution, protecting mechanisms against insects and pathogens, parasitism, plant cancer, and more; helps readers understand the scope and breadth of plant vascular systems in 20 detailed, high-quality chapters; includes a wealth of outstanding original color photographs and illustrations documenting the formation of vascular tissues; provides an in-depth understanding of plant biology by studying their vascular tissues.
  • Digital
    Rabih Chaer, editor.
    Springer2017
    Screening for vascular pathology: current guidelines and recommendations -- Preoperative optimization of the elderly patient prior to vascular surgery --Anesthetic considerations for elderly patients undergoing vascular surgery -- Deep vain thrombosis in the elderly -- Management of chronic venous disease and varicose veins in the elderly -- Cerebrovascular disease in the elderly -- Aortic aneurysm disease in the elderly -- Peripheral arterial disease in the elderly -- Renal failure in the elderly -- Ethical considerations.
  • Digital
    Tulio Pinho Navarro, Alan Dardik, Daniela Junqueira, Ligia Cisneros, editors.
    Springer2017
  • Digital
    Tim Meyer, editor.
    Springer2010
    Part 1. Pre-clinical development -- The Discovery and Characterisation of Tumour Endothelial Markers / Dario Neri and Roy Bicknell -- The Use of Animal Models in the Assessment of Tumour Vascular Disrupting Agents (VDAs) / R. Barbara Pedley and Gillian M. Tozer -- Combination Therapy with Chemotherapy and VDAs / Giulia Taraboletti, Katiuscia Bonezzi and Raffaella Giavazzi -- Lessons from Animal Imaging in Preclinical Models / Lesley D. McPhail and Simon P. Robinson -- Combining Antiangiogenic Drugs with Vascular Disrupting Agents Rationale and Mechanisms of Action / Yuval Shaked, Paul Nathan, Laura G. M. Daenen and Robert S. Kerbel -- Development of Vascular Disrupting Agents / Graeme J. Dougherty and David J. Chaplin -- Part 2. Imaging in the development of vascular disruptive agents -- MRI to Assess Vascular Disruptive Agents / Martin Zweifel and Anwar R. Padhani -- Contrast Ultrasound in Imaging Tumor Angiogenesis / Grzegorz Korpanty and Rolf A. Brekken -- Part 3. Clinical development -- The Clinical Development of Tubulin Binding Vascular Disrupting Agents / Martin Zweifel and Gordon Rustin -- ASA404 (DMXAA): New Concepts in Tumour Vascular Targeting Therapy / Bruce C. Baguley -- Vascular Disruptive Agents in Combination with Radiotherapy / Henry C. Mandeville and Peter J. Hoskin.
  • Digital
    Kazuo Tanishita, Kimiko Yamamoto, editors.
    Springer2016
    Chapter 1 Introduction -- Chapter 2 Fundamentals of Vascular Bio-fluid and Solid Mechanics -- Chapter 3 Fundamentals of Physiology and Biology of Vascular System -- Chapter 4 Hemodynamics in Physio- and Pathological Vessels -- Chapter 5 Cyclic Stretch-Induced Reorganization of Stress Fibers in Endothelial Cells -- Chapter 6 Mechanical Characterization of Vascular Endothelial Cells Exposed to Fluid Shear Stress -- Chapter 7 Tensile Properties of Smooth Muscle Cells, Elastin, and Collagen Fibers -- Chapter 8 Mechanobiology of Endothelial Cells Related to the Formation of Arterial Disease -- Chapter9 Mechanotransduction of Shear Stress by the Endothelium -- Chapter 10 Mechanobiology of Endothelial Cells Related to the Pathogenesis of Arterial Disease -- Chapter 11 Vascular Engineering of Blood Coagulation -- Chapter 12 Vascular Engine ering to Make Blood-Compatible Surface -- Chapter 13 Vascular Engineering of Circulatory Assist Devices -- Chapter 14 Innovations in Measuring Cellular Mechanics -- Chapter 15 Innovation of Vascular Engineering by Mechano-medicine -- Chapter 16 Integrated Vascular Engineering: Vascularization of Reconstructed Tissue -- Chapter 17 Novel Technology to Assay the Multicellular Network: On-Chip Cellomics Technology.-.
  • Digital
    Karl-Juergen Wolf ; with contributions by Zarko Grozdanovic [and others].
    Thieme MedOne Radiology2009
  • Digital
    edited by Joana N. Ramalho, Mauricio Castillo.
    Wiley2014
    Basic principles of UVI / Ana Maria Braz and Jaime Leal Pamplona -- Clinical applications of UVI / Ana Maria Braz, Maria Madalena Patricio, and Joana Ramalho -- Novel applications of UVI / Elsa Azevedo and Pedro Castro -- Basic principles of CTA / Margareth Kimura and Mauricio Castillo -- Intracranial CTA / Isabel R. Fragata and Joana Ramalho -- Extra-cranial CTA / Tiago Baptista and João Lopes Reis -- Basic principles of time-of- flight magnetic resonance angiography (TOF MRA) and MRV (2D and 3D) / Hugo A. Ferreira and Joana Ramalho -- Basic principles of phase contrast magnetic resonance angiography (PC MRA) and MRV / Hugo A. Ferreira and Joana Ramalho -- Time-of-flight magnetic resonance angiography (TOF MRA) and MRV : clinical applications / Mauricio Castillo, Juan Camilo Márquez and Francisco Jose Medina -- Phase contrast magnetic resonance angiography (PC MRA) and flow analysis : clinical applications / Pedro Vilela -- Contrast-enhanced MRA fundamentals and clinical applications / Khurram Javed and Mauricio Castillo -- Intracranial magnetic resonance angiography (MRA), 1.5T versus 3T : advantages and disadvantages / Sara Safder, Benjamin Huang, and Mauricio Castillo -- Time-resolved techniques / Nuno Almeida, David Monteiro, and Daniela Seixas -- DSA : basic principles / Mauricio Castillo -- DSA in clinical practice / Yueh Z. Lee and Mauricio Castillo -- Advanced and future DSA applications / Pedro Vilela -- CT perfusion, basic concepts and clinical applications / Joana Ramalho and Isabel R. Fragata -- Dynamic susceptibility contrast-enhanced MRI perfusion : basic principles and clinical applications / Francisco Medina Valencia, Mauricio Castillo, and Juan Marquez -- Arterial spin labeling (ASL) perfusion basic concepts, artifacts, and clinical applications / Debora Bertholdo and Mauricio Castillo -- Imaging of carotid plaque / Sangam Kanekar -- Basic concepts and clinical applications of intravascular imaging hideki / Sitahara, Peter J. Fitzgerald, Paul G. Yock, and Yasuhiro Honda -- Pediatric vascular imaging techniques and clinical applications / Carla R. Conceio, Rita Lopes da Silva, and Joana Ramalho.
  • Digital
    Mark G. Cowling, editor ; foreword by Maximilian F. Reiser.
    Springer2012
    The Aetiology of Vascular Disease / R. D. Wells -- Assessment of Peripheral Vascular Disease / Mark G. Cowling -- Equipment and Environment / Vikramaditya Prabhudesai -- Consent in Interventional Radiology / F. Coccia and J. S. Freedman -- Drugs Used in Vascular Interventional Radiology / Gordon Dent and Mark G. Cowling -- Day Case Vascular Intervention / Ounali S. Jaffer, Dean Y. Huang and Paul S. Sidhu -- Sites of Arterial Access and the Role of Closure Devices in Percutaneous Arterial Intervention / Jon K. Bell and Nicholas Chalmers -- Aortoiliac Intervention / Rafiuddin Patel and Anthony A. Nicholson -- Femoropopliteal Arterial Intervention / Stefan Müller-Hülsbeck and Heide Preuss -- Crural Arterial Interventions / J. Reekers -- Thrombolysis, Mechanical Thrombectomy and Percutaneous Aspiration Thrombectomy / Gerard S. Goh, Robert Morgan and Anna-Maria Belli -- Upper Limb Arterial Intervention / Douglas R. Turner and Steven M. Thomas -- Carotid and Vertebral Artery Intervention / Stephen D. Goode and Trevor J. Cleveland -- Management of Renal and Visceral Arterial Stenoses / M. G. Cowling -- Endovascular Abdominal Aortic Aneurysm Repair / Andrew England, Micheal Murphy and Richard G. McWilliams -- Endovascular Repair of Thoracic Aortic Aneurysms / H. Rousseau, J. Auriol, C. Lions, V. Benouaich and E. Grunenwald, et al. -- Endovascular Repair of Iliac, Visceral and False Aneurysms / Ralph Jackson and John Rose -- Dialysis Access Management / J. R. Asquith -- Management of Venous Stenoses and Venous Thrombosis / J. R. Asquith -- Inferior Veno-Caval Filters / Matthew Matson -- Management of Venous Insufficiency / D. J. West.
  • Digital
    [edited by] Mark S. Persky, Milton Waner, Francine Blei, Alejandro Berenstein.
    Thieme MedOne Otolaryngology2015
    "Recent developments in the areas of medica/ surgical treatment, laser technology, endovascular techniques, pathological diagnostics, and appropriate radiation protocols have dramatically impacted the evaluation and management of patients with vascular lesions. This new book will appeal to many overlapping specialties. Congenital vascular lesions are seen and treated by a spectrum of physicians including otolaryngologists, pediatric otolaryngologists, facial plastic surgeons, vascular/ interventional radiologists, pediatricians, dermatologists, and general pediatric surgeons"--Provided by publisher.
  • Digital
    Laurie D. DeLeve, Guadalupe Garcia-Tsao, editors.
    Springer2011
    Liver Endothelial Cells: Hemostasis, Thrombosis, and Hepatic Vascular Diseases -- Vascular Liver Disease and the Liver Sinusoidal Endothelial Cell -- Pseudocapillarization and the Aging Liver -- Stellate Cells and the Microcirculation -- Circulatory Injury in Liver Transplantation -- Portal Hypertension: Intrahepatic Mechanisms -- Portal Hypertension: Extrahepatic Mechanisms -- Histological Diagnosis -- Radiological Diagnosis -- Hepatic Vascular Pathology After Hematopoietic Cell Transplantation: Sinusoidal Obstruction Syndrome, Focal Nodular Hyperplasia, and Nodular Regenerative Hyperplasia -- Management: Cirrhotic Portal Hypertension -- Portal Vein Thrombosis -- Budd-Chiari Syndrome -- Congenital Hepatic Vascular Malformations -- Interventional Radiology in the Treatment of Portal Hypertension -- Surgical Intervention for Portal Hypertension -- Liver Transplantation and Vascular Disorders.
  • Digital
    Ajay K. Khanna, Satyendra K. Tiwary, editors.
    Springer2021
    The book covers all aspects of vascular malformations including classification, embryology, genetics, clinical approach, investigations, management, controversies and key points to remember. Chapters cover recent changes in detail in various aspects, such as classification, genetic decoding, minimal intervention, selective approach and investigations for different types. It offers clear guidance on diagnostic protocol and surgical decision making with changing scenario leading to evolving endovascular and radiological interventions. The book is useful for vascular surgeon, pediatric surgeon, general surgeon, plastic surgeon and intervention radiologist as well as clinical research scholars, surgical oncologists and radiologists.
  • Digital
    Eng H. Lo, Josephine Lok, MingMing Ning, Michael J. Whalen, editors.
    Springer2014
    Vascular Mechanisms in CNS Trauma focuses on the vascular aspects of brain and spinal cord trauma.Twenty nine chapters are arranged in three sections:Molecular Mechanisms; Experimental Models and Methods; and Clinical Challenges and Opportunities. The first section addresses topics in the basic biology of brain and spinal cord trauma, ranging from the pathophysiology of cerebral endothelial cells and gliovascular interactions to the role of stem cells in neurovascular repair. The second section covers experimental methods in rodent and in large animal models of CNS injury, as well as the use of biomaterials and biomarkers in studying the mechanisms of tissue response. The third section deals with clinical issues in the monitoring and treatment of the patient with traumatic injury of the brain and spinal cord. Contributors to the book include an integrated mix of basic scientists and clinicians from diverse institutions. By presenting salient issues in CNS trauma from a vascular perspective, this book should make a unique contribution to the understanding of traumatic brain and spinal cord injury.
  • Digital
    Markus Hecker, Dirk J. Duncker, editors.
    Springer2021
    This volume of the series Cardiac and Vascular Biology presents the most relevant aspects of vascular mechanobiology along with many more facets of this fascinating, timely and clinically highly relevant field. Mechanotransduction, mechanosensing, fluid shear stress, hameodynamics and cell fate, are just a few topics to name. All important aspects of vascular mechanobiology in health and disease are reviewed by some of the top experts in the field. This volume, together with a second title on cardiacmechanobiology featured in this series, will be of high relevance to scientists and clinical researchers in the area of vascular biology, cardiology and biomedical engineering.
  • Digital
    [edited by] Mark A. Creager, Joshua A. Beckman, Joseph Loscalzo.
    ClinicalKey2020
    ClinicalKey Nursing2020
    Vascular embryology and angiogenesis -- The endothelium -- Vascular smooth muscle -- Normal mechanisms of vascular hemostasis -- Vascular pharmacology -- Pathobiology of atherosclerosis -- Pathobiology of aortic aneurysms -- Pathobiology of thrombosis -- Pathobiology and assessment of cardiovascular fibrosis -- Pathobiology of vasculitis -- The history and physical examination -- Vascular laboratory testing -- Magnetic resonance imaging -- Computed tomographic angiography -- Catheter-based peripheral angiography -- The epidemiology of peripheral artery disease -- Pathophysiology of peripheral artery disease -- Peripheral artery disease: clinical evaluation -- Medical treatment of peripheral artery disease -- Endovascular treatment of peripheral artery disease -- Reconstructive surgery for peripheral artery disease -- Pathophysiology of renal artery disease -- Clinical evaluation of renal artery disease -- Treatment of renal artery disease -- Epidemiology and pathophysiology of mesenteric vascular disease -- Clinical evaluation and treatment of mesenteric vascular disease -- Vasculogenic erectile dysfunction -- Epidemiology of cerebrovascular disease -- Clinical presentation and diagnosis of cerebrovascular disease -- Prevention and treatment of stroke -- Carotid artery revascularization -- Pathophysiology, clinical evaluation, and medical management of aortic dissection -- Surgical therapy for aortic dissection -- Endovascular therapy for aortic dissection -- Epidemiology and prognosis of aortic aneurysms -- Clinical evaluation of aortic aneurysms -- Surgical treatment of abdominal aortic aneurysms -- Endovascular therapy for abdominal aortic aneurysm -- Overview of vasculitis -- Large vessel vasculitis -- Medium and small vessel vasculitis -- Thromboangiitis obliterans (Buerger disease) -- Kawasaki disease -- Acute arterial occlusion -- Atheroembolism -- Raynaud phenomenon -- Acrocyanosis -- Erythromelalgia -- Pernio (chilblains) -- Epidemiology of venous thromboembolic disease -- Clinical evaluation of venous thromboembolism -- Management of venous thromboembolism -- Varicose veins -- Chronic venous insufficiency -- Pulmonary arterial hypertension -- Pulmonary hypertension in patients with nonpulmonary arterial hypertension -- Diseases of the lymphatic circulation -- Fibromuscular dysplasia -- Vascular infections -- Dermatological manifestations of vascular disease -- Lower extremity ulceration -- Vascular trauma -- Vascular compression syndromes -- Peripheral vascular anomalies, malformations, and vascular tumors.
  • Digital
    edited by Domenico Ribatti.
    Springer2015
    The development of the vascular system : a historical overview / Dominico Ribatti, Beatrice Nico, and Enrico Crivellato -- The corneal pocket assay / Marina Ziche and Lucia Morbidelli -- The mouse hindbrain : an in vivo model to analyze developmental angiogenesis / Alice Plein, Christiana Ruhrberg, and Alessandro Fantin -- Three-dimensional in vitro assay of endothelial cell invasion and capillary tube morphogenesis / Lauar di Blasio, Federico Bussolino, and Luca Primo -- Vascular casting for the study of vascular morphogenesis / Maximilian Ackermann and Moritz A. Konerding -- Cell-based computational modeling of vascular morphogenesis using Tissue Simulation Toolkit / Josephine T. Daub and Roeland M.H. Merks -- miRNAs expression profile in zebrafish developing vessels / Emma Ristori and Stefania Nicoli -- Imaging of cardiovascular development in mammalian embryos using optical coherence tomography / Monica D. Garcia ... [and 3 others] -- Live confocal microscopy of the developing mouse embryonic yolk sac vasculature / Andrew L. Lopez III ... [and 3 others] -- Zebrafish embryo intersegmental vesssels : a tool for investigating sprouting angiogenesis / Chiara Tobia ... [and 3 others] -- Avian area vasculosa and CAM as rapid in vivo pro-angiogenic and antiangiogenic models / Andrew N. Makanya ... [and 3 others] -- Investigating in vitro angiogenesis by computer-assisted image analysis and computational simulation / Diego Guidolin ... [and 3 others] -- A chimeric embryoid body model to study vascular morphogenesis / Yanmei Qi ... [and 4 others] -- Avians as a model system of vascular development / Michael Bressan and Takashi Mikawa -- Microfluidic model of angiogenic sprouting / Jonathan W. Song, Despina Bazou, and Lance L. Munn -- The rat aortic ring model of angiogenesis / Alfred C. Aplin and Roberto F. Nicosia -- The coculture organotypic assay of angiogenesis / Jennifer L. Allen and Harry Mellor.
  • Digital
    Hardik P. Amin, Joseph L. Schindler editors.
    Springer2016
    1. How to prepare for the exam -- 2. Initial stroke evaluation -- 3. Vascular neuroanatomy -- 4. Stroke syndromes -- 5. Epidemiology and risk factors -- 6. Stroke pathophysiology -- 7. Classifications of stroke -- 8. Stroke treatment and management -- 9. Clinical cardiology -- 10. Genetic stroke syndromes -- 11. Special populations -- 12. Special systems -- 13. Intracranial hemorrhage -- 14. Vascular malformations -- 15. Hematologic disorders -- 16. Neuroradiology -- 17. Vascular cognitive disorders -- 18. Stroke rehab -- 19. Pharmacology -- 20. Stroke systems of care -- Index.
  • Digital
    Hardik P. Amin, Joseph L. Schindler, editors.
    Springer2020
    Springer Nature eBook.
    This book provides a concise review for practitioners in preparation for the Vascular Neurology Boards including the Maintenance of Certification exam. A valuable second edition, expertly written text is supplemented with new treatment paradigms as well as new and updated trial results. Beginning with a general overview on how to prepare for the exam, this practical guide emphasizes clinically relevant scientific principles that must be mastered by the stroke clinician. Subsequent chapters examine specific epidemiological risk factors that can cause strokes, and discuss stroke pathophysiology, classification, and vascular neuroanatomy. Further subject analysis extends to specific demographics who are genetically predisposed to experiencing a stroke, including those with comorbidities and preexisting conditions. Closing chapters then focus on systems of treatment, such as stroke rehab, pharmacology, and various systems of care. Vascular Neurology Board Review, Second Edition, is not only written to act as a guide for the neurology resident and fellow, but also as a useful framework for non-neurologists.
  • Digital
    Samer S. Hoz.
    Springer2017
    This book is a guide dedicated to vascular pathologies affecting the central nervous system. It uses a multiple-choice format with more than 340 genuine MCQs in a convenient format that is ideal for self-study. Seven chapters provide comprehensive coverage of core concepts in vascular neurosurgery. The questions are structured and organized so as to offer a step-by-step description of each disease, from the definition, related anatomy, pathology, clinical features, radiology to surgical decisions and operative tricks. Answers and explanations appear directly below the questions to make reading easy. This book is essential for residents across neurosurgical disciplines as it includes most of the neurovascular information neurosurgical residents need to prepare for their certification exam. It is also beneficial for those seeking a refresher or for those preparing for certification maintenance.
  • Digital
    edited by Fernando Vivanco.
    Springer2013
    Proteomics is a rapidly expanding investigation platform in cardiovascular medicine. Driven by major improvements in mass spectrometry (MS) instrumentation and data analysis, the proteomics field has flourished in recent years particularly in the study of complex diseases. These recent advances are characterized by the development of quantitative MS-based methods that promoted the field from primarily identifying proteins to also providing measurements of relative changes in protein levels between different cell states. This progress is reflected in the application of proteomic techniques to vascular pathology. Vascular Proteomics: Methods and Protocols provides up-to-date methods and protocols for the analysis of arteries, cells, lipoproteins, body fluids, and metabolites, with a particular focus on MS-based methods of protein and peptide quantification. Written in the successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible protocols, and notes on troubleshooting and avoiding known pitfalls. Authoritative and easily accessible, Vascular Proteomics: Methods and Protocols is a representative selection of methods that can be a useful resource for experienced proteomics practitioners as well as newcomers interested in becoming acquainted with the practice of proteomic techniques for cardiovascular research.
  • Digital
    Jamal J. Hoballah, Carlos F. Bechara, editors.
    Springer2021
    When the first edition of Vascular Reconstructions was published almost twenty years ago, endovascular surgery was still in its infancy. Endovascular approaches became the preferred initial intervention for many vascular pathologies resulting in a major decrease in open vascular surgical procedures. In order to build upon changes in the management of vascular pathology over the past two decades, this second edition of Vascular Reconstructions was conceived. The first part starts with a review of commonly used vascular instruments and an overview of grafts and sutures used in vascular reconstructions. A detailed chapter on vascular anatomy and exposures is provided to serve as a quick reference before starting a vascular procedure. The remaining chapters in the first part of this book review the basic steps usually performed before and after constructing a vascular anastomosis in addition to thrombectomy and endarterectomy. The second part of this book focuses on the various methods used to conduct a vascular reconstruction, which include primary closure, closure with a patch angioplasty, end-to-end, end-to-side, and side- to-side anastomoses. The various possible modifications used are outlined. The third part of this book reviews the various adjunctive methods used when constructing the proximal or distal anastomoses of an infrainguinal bypass. The fourth part of the book reviews the various modifications that are carried out when constructing the proximal and distal anastomoses of an aortic occlusive or aneurysmal pathology. The vascular anastomoses workshop that inspired the conception of this book is included as an appendix. The fifth part focuses on endovascular therapy and imaging. Vascular Reconstructions: Anatomy, Exposures, and Techniques 2nd Edition aims to make the vascular rotation a pleasant experience for surgical residents, the vascular faculty, recent graduates embarking on conducting vascular reconstructions independently, and healthcare providers who wish to be familiar with the various steps involved in conducting a vascular procedure.
  • Digital
    Jamal J. Hoballah, Alan B. Lumsden, editors.
    Springer2012
    Aneurysmal Disease -- Infrarenal Aortic Aneurysms: New Technologies / Laura E. White, Heitham T. Hassoun -- Treatment of Suprarenal and Juxtarenal AAA with Fenestrated Grafts and Debranching Procedures / Heather P. Park, Mark A. Farber -- Surgeon-Modified Fenestrated and Branched Stent Grafts / Nikolaos Tsilimparis, Joseph J. Ricotta II -- Pelvic Revascularization During Endovascular Aortic Aneurysm Repair / Javairiah Fatima, Gustavo S. Oderich -- Management of Endoleak Following Endovascular Aneurysm Repair / Andrew Misselt, Jafar Golzarian -- Thoracic Endovascular Aortic Repair (TEVAR): New Horizons / Jonathan Bath, Jae-Sung Cho -- Thoracic Aneurysms: Endovascular Procedures for Debranching of Ascending and Isolated Arch Aneurysms / Basel Ramlawi, Michael J. Reardon, Alan B. Lumsden -- Aortic Dissection / Vikas A. Pandey, M. Hamady -- Endovascular Treatment of Traumatic Thoracic Aortic Rupture, Ruptured TAA and AAA / Manish Mehta, Philip S. K. Paty, Sean P. Roddy -- Laparoscopic and Robotic Aortic Surgery / Jean Bismuth -- Popliteal Artery Aneurysm: Endovascular Surgery / Munier Nazzal, Viviane Kazan -- Occlusive Disease -- Carotid Artery Stenting: Current Status / Rabih A. Chaer, Michel S. Makaroun -- Mesenteric Artery Occlusive Disease / Panos Kougias -- Treatment of Renal Artery Stenosis and Fibromuscular Dysplasia / Daynene Vykoukal, Javier E. Anaya-Ayala, Mark G. Davies -- Aortoiliac Occlusive Disease / George Pisimisis, Carlos F. Bechara -- Femoropopliteal Endovascular Interventions / Melhem J. Sharafuddin, Parth B. Amin, Rachael M. Nicholson -- Venous Disease -- Venous Insufficiency, Varicose Veins, and Perforators / Eric K. Peden, Nyla Ismail -- Deep Venous Thrombosis / Hossam F. El-Sayed -- Retrievable Inferior Vena Cava Filters / Joseph J. Naoum -- Miscellaneous -- First Rib Resection and Thoracoscopic Cervical Sympathectomy / Mohammad Bashir, Joss Dean Fernandez, Kalpaj Parekh.
  • Digital
    Alan Dardik, editor.
    Springer2017
    Vascular Surgery: A Global Perspective provides the first review and comparison of the diversity of vascular surgery practice around the world. The book is grouped according to common vascular diseases such as aneurysmal and occlusive arterial disease, as well as venous and lymphatic disease and dialysis access. Each major disease topic includes multiple chapters written by expert specialists from around the world, each discussing their local approach to the disease and its treatment. Similarly, the status of vascular surgery practice is addressed, including discussion of the influence of payment systems on practice, patient access to the internet for information, training paradigms, and the legal system including malpractice. This textbook provides the first worldwide summary of the care of patients with vascular disease and will be of interest to a wide audience including vascular surgeons, vascular medical specialists, cardiologists, radiologists, internists, and family practice physicians.
  • Digital
    George Geroulakos, Bauer Sumpio (Editors).
    Springer2011
    Part 1. Arterial Aneurysms -- Preoperative Cardiac Risk Assessment and Management of Elderly Men with an Abdominal Aortic Aneurysm -- Abdominal Aortic Aneurysm -- Endoluminal Treatment of Infra-renal Abdominal Aortic Aneurysm -- Ruptured Abdominal Aortic Aneurysm -- Thoracoabdominal Aortic Aneurysm -- Endovascular Management of Thoracic Aneurysm -- Aortic Dissection -- Popliteal Artery Aneurysms -- Renal Artery Aneurysm -- Anastomotic Aneurysms -- False Aneurysm in the Groin Following Coronary Angioplasty -- Acute Thrombosis -- Part 2. Acute Ischemia -- Arterial Embolism -- Blast Injury to the Lower Limb -- Endovascular Management of Aortic Transection in a Multiinjured Patient -- Part 3. Management Of Chronic Ischaemia of the Lower Extremities -- Cardiovascular Risk Factors and Peripheral Arterial Disease -- Lower Limb Claudication Due to Iliac Artery Occlusive Disease -- Lower Limb Claudication Due to Bilateral Iliac Artery Occlusive Disease: The Case for Iliac Stenting and Femorofemoral Crossover Bypass -- Endovascular Management of Lower Limb Claudication due to Infra-Inguinal Disease -- Endovascular Management of Non-Healing Leg Ulceration -- Bypass to the Popliteal Artery -- Bypass to the Infrapopliteal Arteries for Chronic Critical Limb Ischemia -- Popliteal Artery Entrapment -- Adventitial Cystic Disease of the Popliteal Artery -- The Obturator Foramen Bypass -- Diabetic Foot -- Part 4. Surgery of the Major Branches of the Infradiaphragmatic Aorta -- Chronic Visceral Ischemia -- Acute Mesenteric Ischemia -- Renovascular Hypertension -- Midaortic Syndrome -- Part 5. Management of Popliteal Hypertension -- Management of Portal Hypertension -- Part 6. Management of Extracranial Cerebrovascular Disease -- Management of Carotid Bifurication Disease -- The Carotid Body Tumor -- Vertebrobasilar Ischemia: Embolic and Low-Flow Mechanisms -- Takayasus Arteritis Associated with Cerebrovascular Ischemia -- Part 7. Neurovascular Conditions of the Upper Extremity -- Neurogenic Thoracic Outlet Syndrome and Pectoralis Minor Syndrome -- Acute Axillary/Subclavian Vein Thrombosis -- Raynauds Phenomenon -- Part 8. Prevention and Management of Complications of Arterial Surgery -- Aortofemoral Graft Infection -- Aortoenteric Fistulas -- Part 9. Vascular Access -- The Optimal Conduit for Hemodialysis Access -- Acute Ischemia of the Upper Extremity Following Graft Arteriovenous Fistula -- Part 10. Amputations -- Amputations in an Ischemic Limb -- Part 11. Vascular Malformations -- Congenital Vascular Malformation -- Klippel-Trenaunay Syndrome -- Part 12. Management of Venous Disorders -- Deep Venous Thrombosis -- Endoluminal Ablation of Varicose Veins -- Ultrasound Guided Foam Sclerotherapy for the Management of Recurrent Varicose Veins -- Venous Ulcers Associated with Deep Venous Insufficiency -- Venous Ulcers Associated with Superficial Venous Insufficiency -- Iliofemoral Venous Thrombosis -- Iliofemoral Deep Venous Thrombosis During Pregnancy -- Part 13. Lymphodema -- Management of Chronic Lymphedema of the Lower Extremity -- Management of Upper Extremity Lymphoedema with Microsurgical Lympho-Venous Anastomosis (LVA).
  • Digital
    George Geroulakos, Bauer Sumpio, editors.
    Springer2018
  • Digital
    edited by R. Clement Darling III, C. Keith Ozaki.
    LWW Health Library2016
    Resection of carotid artery aneurysms / Brandon W. Propper and Christopher J. Abularrage -- Carotid endarterectomy: conventional and eversion / R. Clement Darling III and W. John Byrne -- Carotid subclavian reconstructions / Mark D. Morasch -- Vertebral artery reconstruction / Enrique Criado -- Carotid bypass / W. John Byrne and Nishan Dadian -- Brachial artery embolectomy / Chinenye Iwuchukwu and Vivian Gahtan -- Distal upper extremity revascularization (brachial to radial/ulnar/hand bypass) / Philip S.K. Paty and Benjamin B. Chang -- Open thoracoabdominal aneurysm repair / Ralph Bolman and Tsuyoshi Kaneko -- Open repair of Type B dissection / Paul R. Crisostomo and Jae S. Cho -- Thoracobifem for occlusive disease / Vikram Kashyap and Nathaniel Liu -- Visceral aortic endarterectomy / Timur P. Sarac -- Antegrade aorto-SMA and celiac artery bypass / William J. Quinones-Baldrich -- Retrograde ilio-SMA and celiac bypass / James McPhee and Thomas N. Carruthers -- SMA embolectomy / W. Charles Sternbergh and Hernan Bazan -- Open repair of renal artery aneurysm / Paul B. Kreienberg and Jason Comeau -- Type IV thoracoabdominal aneurysm repair / Mark Conrad -- Division of the crus and celiac artery reconstruction for celiac artery compression syndrome / Glen Roseborough. Aortic repair for juxtarenal and suprarenal aneurysms / Richard Cambria and V. Patel -- Aortofemoral bypass for occlusive disease: end-to-end and end-to-side / Daniel B. Walsh and David H. Stone -- Transaortic endarterectomy / Margaret C. Tracci, Kenneth J. Cherry, and Gilbert R. Upchurch, Jr. -- Iliofemoral reconstruction : ipsilateral and crossover / Richard F. Neville and Bao Nguyen -- Fermoral-femoral bypass / Amy B. Reed -- Femoral endarterectomy with profundaplasty / Michael Belkin and James T. McPhee -- Fermoropopliteal bypass using prosthetic and vein / Neal Barshes -- Femoral distal bypass using the in situ and reversed vein / Scott G. Prushik and Frank B. Pomposelli -- Exposure of tibial vessels: anterior tibial, posterior tibial, peroneal, from both medial and lateral approaches / Michael S. Conte and Shant Vartanian -- Plantar and tarsal artery reconstructions / Enrico Ascher, Anil Hingorani, Natalie Marks, and Frank J. Veith -- Technique of carotid artery stenting / Piotr Sobieszczyk -- TEVAR for thoracoabdominal aneurysm repair / Gustavo S. Oderich and Tiziano Tallarita -- TEVAR for acute and chronic aortic dissection / Joseph Lombardi and Carlos A. Neves -- EVAR for traumatic aortic injuries / S. Bahimi -- EVAR for infrarenal abdominal aortic aneurysm repari / Jeffrey C. Hnath -- Endovascular repair of thoracoabdominal aortic aneurysms / W. Anthony Lee -- Endovascular repair of juxtarenal aneurysms / John C. McCallum, Matthew J. Alef, and Marc L. Schermerhorn -- Renal artery stenting for renovascular hypertension / Matthew J. Dougherty -- SMA and visceral artery stenting / Hari Ramachandran Kumar and Mark K. Eskandari -- Endovascular treatment of aortoiliac disease / Sean P. Lyden and David M. Hardy -- Endovascular treatment of the SMA (angioplasty & stent, subintimal angioplasty, atherectomy) / George H. Meier -- Endovascular treatment of tibial vessels / Charlie C. Cheng, Faisal Z. Cheema, Grant T. Fankhauser, and Michael B. Silva, Jr. -- Translumbar approach for coiling of Type II endoleaks / Courtney J. Warner, Claire L. Griffin, and Eva M. Rzucidlo.
  • Digital
    edited by R. Clement Darling III, MD, Professor of Surgery, Albany Medical College, Chief, Division of Vascular Surgery, Albany Medical Center Hospital, Director, The Institute for Vascular Health and Disease, President, The Vascular Group, Albany, New York, C. Keith Ozaki, MD, John A. Mannick Professor of Surgery, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts ; illustrations by: Body Scientific International, LLC., Anne Rains, Arains Illustration, Inc.
    LWW Health Library2016
    Proximal debranching using the ascending aorta for bypasses to carotid, innominate, and subclavian arteries with endovascular repair of thoracic and arch aneurysms / Mark A. Farber and Jason Crowner -- Visceral debranching with repair of descending thoracic and visceral aortic aneurysm / S.W. Ham, M. Sigman, and Fred Weaver -- Combined iliac stent with femoral endarterectomy / Richard J. Powell -- Combined iliac stenting and fem-fem bypass / William C. Pevec -- Retrograde SMA angioplasty and stenting in patients with acute intestinal ischemia / Mark C. Wyers -- Endovascular composite sequential bypass using covered SFA graft and vein bypass for distal reconstruction / Mark Patterson -- Central venous dilatation and stenting / Murray L. Shames and Alexis Powell -- Treatment of superior vena cava syndrome and central stenosis / Peter Gloviczki and Sameh Said -- Placement of IVC filter and removal of retrievable filters / Roan J. Glocker and Marc A. Passman -- Lysis for iliofemoral DVT / Omar Al-Nouri and Bernadette Aulivola -- Endovascular interventions for Paget-Schroetter/venous thoracic outlet syndrome / Mitchell W. Cox and Cynthia K. Shortell -- Endovascular treatment for May-Thurner syndrome / Philip P. Goodney and Courtney J. Warner -- Endovascular treatment for pelvic congestion syndrome / Carl M. Black and Ellen D. Dillavou -- Saphenous vein ablation and stab phlebectomy / Kathleen J. Ozsvath and Stephanie S. Saltzberg -- Vena cava resection for renal cell carcinoma / R. Clement Darling III, Chin Chin Yeh, and John B. Taggert. Upper extremity permanent hemodialysis access placement / William Jennings, Alexandros Mallios, and John Blebea -- Lower extremity permanent hemodialysis access placement / Paul B. Kreienberg -- Peritoneal dialysis access placement / Claudie Sheahan, Bruce Torrance, and Malachi G. Sheahan -- Procedures for hemodialysis access steal syndrome / Karen J. Ho and Haimanot Wasse -- Hemodialysis access maintenance and salvage / Dirk M. Hentschel -- Supraclavicular/infraclavicular / Louis L. Nguyen -- Thoracic outlet procedures: transaxillary approach / Dean J. Arnaoutakis and Julie A. Freischlag -- Drainage and debridement of foot infections / Neal R. Barshes -- Digital and metatarsal ampurtations of the forefoot / Nicholas A. Giovinco, David G. Armstrong, and Joseph L. Mills -- Syme and Lisfranc disarticulations / Christopher P. Chiodo and Jeremy T. Smith -- Ankle disarticulation and circular open (guillotine) below-knee amputation / C. Keith Ozaki -- Closed below-knee amputation / Jonathan D. Gates -- Knee disarticulation / Marcus Semel -- Above knee amputation / Jacob Bray and Malachi G. Sheahan -- Hip disarticulation / I. Koleilat and A. Nigam.
  • Digital
    Melvin A. Shiffman, Mervin Low, editors.
    Springer2020
  • Digital
    Paula E. North, Tara Sander, editors.
    Springer2016
    Histopathology and Pathogenesis of Vascular Tumors and Malformations -- Vascular Overgrowth -- Vasculogenesis and Angiogenesis -- The Genetic Basis and Molecular Diagnosis of Vascular Tumors and Developmental Malformations -- Clinical Management and Treatment of Vascular Tumors.
  • Digital
    Walter Grand, L. Nelson Hopkins, Adnan Siddiqui, J. Mocco.
    Thieme-Connect2016
    Thieme MedOne Neurosurgery2016
    Basic anatomy -- External carotid artery -- Internal carotid artery -- Carotid-ophthalmic triangle -- Posterior communicating artery and anterior choroidal artery -- Middle cerebral artery -- Anterior cerebral and anterior communicating arteries -- Basilar bifurcation and posterior cerebral arteries -- Vertebral and basilar arteries -- Venous anatomy.
  • Digital
    Richard A. Watts, David G.I. Scott, Chetan Mukhtyar.
    Springer2015
    In this second edition, the authors discuss the newly discovered entity of IgG4 related diseases, look in greater detail at the role of biologic treatment in ANCA associated vasculitis, and have revised the nomenclature in each chapter to reflect international consensus. The addition of illustrations as well as online video content helps the reader manage patients with these potentially devastating conditions. Vasculitis in Clinical Practice, Second Edition, is a useful and concise volume that will help physicians in training, primary care physicians and nurse practitioners in quickly and easily recognizing the key and salient points of each condition.
  • Digital
    Paulo Roberto Barbosa Evora, Andrea Carla Celotto, Agnes Afrodite Sumarelli Albuquerque, Patricia Martinez Évora.
    Springer2021
    This unique work presents one of the most significant organ failure condition--cardiocirculatory shock--and the prominent role of Methylene Blue (MB). Through their extensive experience, the authors consider that the lifesaving feature of MB is still underestimated. For this reason they outline key concepts of MB, mentioning essential experimental data, yet focusing mainly on its application in the care of critically ill patients. In an easy-to-read format, the 18 chapters were organized in a didactically structured order, distributed in four parts. The first part introduces the general conceptual aspects and physiology of the endothelium. The second part presents the particularities of endothelial dysfunction in different types of shock. Methylene blue is discussed in detail in the third part. In the fourth part, particular situations of endothelial dysfunction, such as heart surgery and organ transplantation, are described. Additionally, the two complementary subjects of acid-base balance and the therapeutic use of inhaled nitric oxide are mentioned. Finally, looking for therapeutic alternatives for what we classify as "vasoplegic endothelial dysfunction", MB remains promising as an adjuvant to sympathomimetic amines. The combination of three recently proposed concepts may be useful in obtaining better results against the high mortality rates in critically ill patients. These three concepts are "wide-spectrum vasopressors", vasopressor economy strategies, and microcirculation protection against the harmful effects of using high concentrations of amines. This book's translational approach will appeal to a variety of readers within the health specialties of medicine, biomedicine, physiotherapy, nursing, odontology, and basic science.
  • Digital
    Paolo Alboni, Raffaello Furlan, editors.
    Springer2015
    This book is exceptional in being devoted solely to vasovagal syncope (VVS), the most frequent cause of transient loss of consciousness in the general population. All aspects of VVS are covered, including epidemiology, pathophysiology, diagnosis and differential diagnosis, prognosis, therapy and implications for particular activities such as work, driving and physical activity. The context for the book is that about half of the population suffer from this type of loss of consciousness during their lifetime and then often call for general practitioner and/or emergency room assistance. While many pathophysiological aspects of VVS have been clarified, others remain elusive. The diagnosis of VVS may be easy, but it is sometimes challenging. From the therapeutic standpoint, few evidence-based therapies have been established and the large majority of treatments remain unsatisfactory. Vasovagal Syncope presents the latest evidence on all these issues and will be of value for internists, cardiologists, neurologists, emergency physicians and general practitioners.
  • Digital/Print
    Asbury, Taylor; Augsburger, James J.; Cunningham, Emmett T.; Riordan-Eva, Paul; Vaughan, Daniel; Whitcher, John.
    Digital : AccessMedicine19th ed. (2018)latest ed. only.
    Digital : AccessMedicine18th ed. (2011)latest ed. only.
  • Digital
    Sabine Krist.
    Springer2020
  • Digital
    Marja Mutanen, Anne-Maria Pajari, editors.
    Springer2011
    Cruciferous vegetables and biological activity of isothiocyanates and indoles -- Green leafy vegetables in cancer prevention -- The role of tomato lycopene in cancer prevention -- [Beta]-carotene and other carotenoids in cancer prevention -- The role of alliums and their sulfur and selenium constituents in cancer prevention -- Molecular mechanisms of chemoprevention with capsaicinoids for chili peppers -- Influence of dietary soy isoflavones genistein and daidzein on genotoxicity and mammary carcinogenicity in rats exposed to the model carcinogen 7, 12-dimethylbenz[a]anthracene (DMBA) -- The potential roles of seeds and seed bioactives on the prevention and treatment of breast and prostate cancer -- Nuts as part of a whole diet approach to cancer prevention -- Whole grains and their constituents in the prevention of colon cancer.
  • Digital
    Dilfuza Egamberdieva, Münir Öztürk, editors.
    Springer2018
    Central Asia is a large and understudied region of varied geography, ranging from the high passes and mountains of Tian Shan, to the vast deserts of Kyzyl Kum, Taklamakan to the grassy treeles steppes. This region is faced with adverse conditions, as much of the land is too dry or rugged for farming. Additionally, the rich specific and intraspecific diversity of fruit trees and medicinal plants is threatened by overgrazing, oil and mineral extraction, and poaching. Countless species from the approximately 20 ecosystems and 6000 plant taxa are now rare and endangered. Traditional vegetation studies in this region are far from adequate to handle complex issues such as soil mass movement, soil sodicity and salinity, biodiversity conservation, and grazing management. However, data analysis using a Geographical Information System (GIS) tool provides new insights into the vegetation of this region and opens up new opportunities for long-term sustainable management. While vegetation planning can occur at a property scale, it is often necessary for certain factors, such as salinity, to be dealt with on a regional scale to ensure their effective management. GIS increases the effectiveness and accuracy of vegetation planning in a region. Such regional planning will also greatly increases biodiversity values. This book systematically explores these issues and discuses new applications and approaches for overcoming these issues, including the application of GIS techniques for sustainable management and planning. Professional researchers as well as students and teachers of agriculture and ecology will find this volume to be an integral resource for studying the vegetation of Central Asia.
  • Digital
    edited by Lorna Fiedler.
    Springer2015
    VEGF splicing and the role of VEGF splice variants: From physiological-pathological conditions to specific pre-mRNA splicing -- Detection and quantification of VEGF isoforms by ELISA -- Quantitation of circulating neuropilin-1 in human, monkey, mouse, and rat sera by ELISA -- Detection and quantification of vascular endothelial growth factor receptor tyrosine kinases in primary human endothelial cells -- Induction of VEGF secretion in cardiomyocytes by mechanical stretch -- Chromatin immunoprecipitation assay: Examining the interaction of NFkB with the VEGF promoter -- An overview of vegf-mediated signal transduction -- Identification of receptor tyrosine kinase inhibitors using cell surface biotinylation and affinity isolation -- Analysis of VEGF-mediated ERK5 activity in endothelial cells -- In vitro angiogenesis assays -- Chemotactic migration of endothelial cells towards VEGF-A165 -- Vasculogenesis and angiogenesis in VEGF receptor-1 deficient mice -- The embryonic mouse hindbrain and postnatal retina as in vivo models to study angiogenesis -- VEGF gene transfer to the utero-placental circulation of pregnant guinea pigs to enhance fetal growth -- VEGF gene transfer to the utero-placental circulation of pregnant sheep to enhance fetal growth -- Generation of targeted mutations in zebrafish using the CRISPR/cas system.
  • Digital
    posted by Atul Gawande.
  • Digital
    edited by P. Gopalakrishnakone, Juan J. Calvete.
    Springer2014
    In recent years, the field of Toxinology has expanded substantially. On the one hand it studies venomous animals, plants and micro organisms in detail to understand their mode of action on targets. While on the other, it explores the biochemical composition, genomics and proteomics of toxins and venoms to understand their three interaction with life forms (especially humans), development of antidotes and exploring their pharmacological potential. Therefore, Toxinology has deep linkages with biochemistry, molecular biology, anatomy and pharmacology. In addition, there is a fast developing applied subfield, clinical toxinology, which deals with understanding and managing medical effects of toxins on human body. Given the huge impact of toxin-based deaths globally, and the potential of venom in generation of drugs for so-far incurable diseases (for example, Diabetes, Chronic Pain), the continued research and growth of the field is imminent. This has led to the growth of research in the area and the consequent scholarly output by way of publications in journals and books. Despite this ever growing body of literature within biomedical sciences, there is still no all-inclusive reference work available that collects all of the important biochemical, biomedical and clinical insights relating to Toxinology. The Handbook of Toxinology aims to address this gap and cover the field of Toxinology comprehensively.
  • Digital
    Scott A. Weinstein, David A. Warrell, Julian White and Daniel E. Keyler.
    ScienceDirect2011
    This book is the first significant contribution to thoroughly examine the potential hazards associated with snakes of the former family, Colubridae. This family contained >65% of living snake species (approximately 3,000 taxa) and has recently been split into multiple families. Many of these snakes produce oral secretions that contain toxins and other biologically-active substances. A large variety of these snakes figure in the pet industry, yet little documented information or formal study of their potential medical importance has been published. Therefore, although the possible medical importance of many of these species has been subjected to speculation since the mid-nineteenth century, there is a limited amount of useful descriptive information regarding the real hazard (or lack thereof) of snakes belonging to this diverse, artificial family. There is a need for "one-stop shopping" offering information regarding their possible toxicity and clinical relevance as well as recommendations for medical management of their bites. This book is the first synthesis of this information and includes evidence-based risk assessment, hazard rankings and specific recommendations regarding important species, many common in captivity. Fills a gap in the toxinological, medical and herpetological literature by providing a comprehensive review of this entire assemblage of snakes, with particular attention given to their capacity, real or rumored, to cause harm to humans A patient-centered, evidence-based approach is applied to analyzing documented case reports of bites inflicted by approximately 100 species. Clinical management of medically significant bites from non-front-fanged colubroids is methodically reviewed, and specific recommendations are provided.
  • Digital
    Ajay K. Khanna, Ravul Jindal, editors.
    Springer2018

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Derived from Current Medical Diagnosis & Treatment, AccessMedicine's Quick Medical Diagnosis & Treatment provides topic reviews with key diagnostic and treatment features for more than 500 diseases.

A repository of medical knowledge from internal medicine, cardiology, genetics, pharmacy, diagnosis and management, basic sciences, patient care, and more.

Continuously expanding, all databases in the repository contain the latest editions of selected medical titles.

MicroMedex: Premier pharmaceutical information source containing multiple databases and drug reference tools. Of particular value is DRUGDEX Evaluations, one of the most comprehensive drug sources available. DynaMed is a clinical information resource used to answer questions quickly at the point-of-care. Easy-to-interpret Levels of Evidence help clinicians rapidly determine the quality of the available evidence.

Biomedical and pharmacological abstracting and indexing database of published literature, by Elsevier. Embase® contains over 32 million records from over 8,500 currently published journals (1947-present) and is noteworthy for its extensive coverage of the international pharmaceutical and alternative/complementary medicine literature.

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Includes cited reference searching, citation maps, and an analyze tool.

Features systematic reviews that summarize the effects of interventions and makes a determination whether the intervention is efficacious or not.

Cochrane reviews are created through a strict process of compiling and analyzing data from multiple randomized control trials to ensure comprehensiveness and reliability.

Provides systematic coverage of the psychological literature from the 1800s to the present through articles, book chapters and dissertations.BMJ Clinical Evidence. A clinical information tool built around systematic reviews summarizing the current state of knowledge about prevention and treatment of clinical conditions. PIER (Physicians' Information and Education Resource) is a Web-based decision-support tool designed for rapid point-of-care delivery of up-to-date, evidence-based guidance for primary care physicians. Cochrane Central Register of Controlled Trials (CENTRAL) provides access to 300,000 controlled trials that have been identified the Cochrane Collaboration.Provides drug information targeted for patients. A continually updating drug monograph.ECRI Guidelines Trust: A comprehensive database of evidence-based clinical practice guidelines and related documents.MedlinePlus: A repository of health information from the National Library of Medicine. Links are from trusted sites. No advertising, no endorsement of commercial companies or products LPCH CareNotes via MicroMedex: Patient education handouts customized by LPCH clinical staff Micromedex Lab Advisor: Evidence based laboratory test informationA drug database organized by generic name, trade name and drug class. LPCH / Stanford Hospital Formulary. A goldmine of trusted consumer health information from the world's largest medical library. A trusted source of expert advice for and about kids, providing the information necessary to help patients and parents understand their unique needs. Provides patient handouts from the American Academy of Family Physician. Access to the Stanford Health Library for patients.Lane provides access to over 5,000 eBooks many of which provide helpful background material that will prepare you to better tackle primary literature.

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A collection of biomedical books that can be searched directly by concept, and linked to terms in PubMed abstracts.

A web-based, decision support system for infectious diseases, epidemiology, microbiology and antimicrobial chemotherapy. The database, updated weekly, currently includes 337 diseases, 224 countries, 1,147 microbial taxa and 306 antibacterial (-fungal, -parasitic, -viral) agents and vaccines.

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Large number of high quality software and database programming titles from O'Reilly. Other software titles are also available from Sams and Prentice Hall. Limited to 7 concurrent users. Vast collection of software and database programming titles from multiple publishers, including Microsoft Press. Largest provider of engineering-related eBooks; includes titles in computer science and biomedical engineering. Over 4,000 full-text e-books covering scientific and technical information from CRC Press and others. Many handbooks and single volume reference sources. Includes peer-reviewed life science and biomedical research protocols compiled from Methods in Molecular Biology, Methods in Molecular Medicine, Methods in Biotechnology, Methods in Pharmacology and Toxicology, Neuromethods, the Biomethods Handbook, the Proteomics Handbook, and Springer Laboratory Manuals. Contains full text access to selected biomedical and nursing books.

Provides online, full-text access to Springer's journal titles as well as journals from other publishers.

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Collection of over 8 thousand fulltext titles in engineering, math, and basic and applied biomedical research. Coverage is from 1967 to the present. A library of ebooks on a wide array of topics, digitized and made available online in conjunction with the original publishers.