Books

::Summary## "Reduce stress, release pain, and create bodily harmony with this introduction to qigong and the yin/yang balance of tai chi, the ancient Chinese arts of movement meditation. This accessible book features information about these practices as well as insights into their benefits, providing tools for replenishing inner resources and managing energy levels. It also offers advice on making healthier choices in everyday life that will support the body's natural capacity for energy, balance, and well-being"-- Provided by publisher.

::Summary## Miles, Huberman, and Saldaña's Qualitative Data Analysis: A Methods Sourcebook is the authoritative text for analyzing and displaying qualitative research data. The Fourth Edition maintains the analytic rigor of previous editions while showcasing a variety of new visual display models for qualitative inquiry. Graphics are added to the now-classic matrix and network illustrations of the original co-authors. Five chapters have been substantially revised, and the appendix's annotated bibliography includes new titles in research methods. Graduate students and established scholars from all disciplines will find this resource an innovative compendium of ideas for the representation and presentation of qualitative data. As the authors demonstrate, when researcheres "think display," their analyses of social life capture the complex and vivid processes of the people and institutions studied. -- From back cover.<br/>::Contents##<br/>Part I. The substantive start. Introduction ; Research design and data management ; Ethical issues in analysis ; Fundamentals of qualitative data analysis<br/>Part II. Displaying the data. Designing matrix, network, and graphic displays ; Methods of exploring<br/>; Methods of describing ; Methods of ordering ; Methods of explaining ; Methods of predicting<br/>Part III. Making good sense. Drawing and verifying conclusions ; Writing about qualitative research<br/>Closure.

::Summary## "Engaging and accessible, this book offers students a complete guide to using NVivo for qualitative data analysis. Drawing on their wealth of expertise, the authors offer detailed, practical advice that relates to students' own experience and research projects. Packed with real-world examples and case studies, the book supports students through every stage of qualitative data analysis."--Provided by publisher<br/>::Contents##<br/>Chapter 1: Where to begin?<br/>Chapter 2: Designing an NVivo project<br/>Chapter 3: Coding foundations<br/>Chapter 4: Advanced coding<br/>Chapter 5: Cases, classifications and comparisons<br/>Chapter 6: Surveys and mixed methods<br/>Chapter 7: Querying data<br/>Chapter 8: Literature reviews and PDF files<br/>Chapter 9: Working with multimedia files<br/>Chapter 10: Twitter, Facebook, YouTube and web pages<br/>Chapter 11: Teamwork<br/>Chapter 12: Moving on<br/>further resources.

::Summary## Patton has created the most comprehensive, systematic, and up-to-date review of qualitative methods available. The Third Edition has retained and expanded upon the exhibits, which highlight and summarize major issues, guidelines, the summative sections, tables, and figures as well as the sage advice of the Sufi-Zen master, Halcolm. This revision will help readers integrate and make sense of the great volume of qualitative works published in the past decade.<br/>::Contents##<br/>The nature, niche, value, and fruit of qualitative inquiry<br/>Strategic themes in qualitative inquiry<br/>Variety of qualitative inquiry frameworks : paradigmatic, philosophical, and theoretical orientations<br/>Practical and actionable qualitative applications<br/>Designing qualitative studies<br/>Fieldwork strategies and observation methods<br/>Qualitative interviewing<br/>Qualitative analysis and interpretation<br/>Enhancing the quality and credibility of qualitative studies.

::Summary## "Now in its fourth edition, this essential introduction to conducting and interpreting qualitative research is fully revised and updated with new material examining the impact of the web research and social media, data mining and co- designing. This concise, practical and easy-to-use guide continues to show how qualitative research can be employed effectively and appropriately to answer some of the questions confronting health care researchers today"-- Provided by publisher.<br/>::Contents##<br/>Introduction<br/>The role of theory in qualitative research<br/>Ethical issues in qualitative research<br/>Interviews<br/>Focus groups<br/>Observational methods<br/>Documentary analysis<br/>Digital data and online qualitative research<br/>Analysis<br/>Conversation analysis<br/>Synthesising qualitative research<br/>Mixed methods research<br/>Case studies<br/>Participatory research in health care<br/>Quality in qualitative research.

::Contents##<br/>Part I: Performance improvement model. Introduction and history of performance improvement<br/>Defining a performance improvement model<br/>Identifying improvement opportunities based on performance measurement<br/>Using teamwork in performance improvement<br/>Aggregating and analyzing performance improvement data<br/>Communicating performance improvement activities and recommendations<br/>Part II: Continuous monitoring and improvement functions. Measuring customer satisfaction<br/>Refining the continuum of care<br/>Improving the provision of care, treatment, and services<br/>Preventing and controlling infectious disease<br/>Decreasing risk exposure<br/>Building a safe medication management system<br/>Managing the environment of care<br/>Developing staff and human resources<br/>Part III: Management of performance improvement programs. Organizing and evaluating performance improvement<br/>Navigating the accreditation, certification, or licensure process<br/>Implementing effective information management tools for performance improvement<br/>Managing healthcare performance improvement projects<br/>Managing the human side of change<br/>Understanding the legal implications of performance improvement.

::Summary## "The Third Edition of Quality and Safety Education for Nurses has been thoroughly updated for students in undergraduate Associate, Baccalaureate, Accelerated and BSN completion Nursing programs. There is a chapter focusing on each of the six Quality and Safety Education for Nurses (QSEN) Competency areas, with content on Nursing Leadership and Patient Care Management infused throughout the chapters. The Third Edition also includes new chapters on Systems Thinking, Implementation Science, and Population Health. It includes an Instructor's manual and Powerpoints"-- Provided by publisher.<br/>::Contents##<br/>Intro<br/>Title<br/>Copyright<br/>Dedication<br/>Contents<br/>Contributors<br/>Foreword<br/>Preface<br/>Why This Book?<br/>Chapter Features<br/>Highlights of the Text<br/>Instructor Resources<br/>References<br/>Acknowledgments<br/>Unit I: Role of the Nurse in Healthcare<br/>Chapter 1: Patient Safety and Quality of Care as Measures of Nursing Competence<br/>Introduction<br/>Quality of Care and Patient Safety<br/>Drivers for Quality and Safety<br/>National Organizations Impacting Healthcare Improvement<br/>Global Advances in Quality and Safety<br/>The Patient Safety Movement to Improve Quality and Safety The Cost of Achieving Quality and Safety<br/>Recognizing Healthcare Excellence<br/>The Beginning of Quality and Safety Education for Nurses<br/>Integration of the Quality and Safety Education Competencies Into Nursing Education<br/>Integration of the Knowledge, Skills, and Attitudes Into Nursing Curricula<br/>Applying the Quality and Safety Education Competencies in Practice<br/>Patient-Centered Care<br/>Teamwork and Collaboration<br/>Evidence-Based Practice<br/>Quality Improvement<br/>Safety<br/>Informatics<br/>Nurses' Role in Quality and Safety as Direct Care Providers and Leaders Recognizing Nursing Excellence<br/>The Role of Nurse Leaders in Ensuring Quality and Safety<br/>Accreditation and Evaluation of Quality and Safety Education for Nurses Competencies<br/>End-Of-Chapter Resources<br/>Key Concepts<br/>Critical Discussion Points<br/>Key Terms<br/>Review Questions<br/>Review Activities<br/>Exploring The Web<br/>References<br/>Chapter 2: Nurses as Leaders and Managers for Safe, High-Quality Patient Care<br/>Introduction<br/>Value of Enhancing Leadership Skills of Nurses at the Bedside<br/>Apply Leadership and Management Theory to Transform Nursing Practice to Improve Care Roles and Education of Nurses Leading and Managing Quality Care<br/>Motivating Nurses on the Frontline of Patient Care to Lead and Manage Quality Improvement<br/>Organizational Structures in Hospital Healthcare Settings<br/>Leadership and Management Influence an Organization's Culture<br/>Events to Mark the Advancement of Nursing as a Profession<br/>Professional Development and Education is a Life-Long Endeavor<br/>Benefits of Membership in Nursing Organizations<br/>Learning Systems and Innovation for Safe, High-Quality Patient Care<br/>Leadership and Management Skills Transfer to Crisis Management Key Concepts<br/>End-Of-Chapter Resources<br/>Critical Discussion Points<br/>Key Terms<br/>Review Questions<br/>Review Activities<br/>Exploring the Web<br/>References<br/>Suggested Readings<br/>Chapter 3: Systems Thinking<br/>Introduction<br/>Define the Theoretical Principles of a System<br/>Systems Theory in Other Fields<br/>Define Systems Thinking<br/>Looking at the Big Picture<br/>Recognizing Patterns<br/>Reflection<br/>Willingness to Change<br/>Applying Systems Thinking to Nursing Practice<br/>Identify the Origins of Systems Thinking in Healthcare<br/>Historical Development of Systems Thinking in Healhcare

::Contents##<br/>Patient safety : a brief history / Robert K. Stoelting<br/>Cognitive load theory and patient safety / Elizabeth Harry and John Sweller<br/>Errors and violations / Alan F. Merry<br/>The human-technology interface / Frank A. Drews and Jonathan R. Zadra<br/>Deliberate practice and acquisition of expertise / Keith Baker<br/>Fatigue / Michael Keane<br/>Situational awareness / Christian Schulz<br/>Creating a culture of safety / Thomas R. Chidester<br/>Adverse event prevention and management / Patrick J. Guffey and Martin Culwick<br/>Complex systems and approaches to quality improvement / Loren Riskin and Alex Macario<br/>Crisis resource management and patient safety in anesthesia practice / Amanda R. Burden, Jeffrey B. Cooper, and David M. Gaba<br/>Quality in medical education / Viji Kurup<br/>Regulating quality / Robert S. Lagasse<br/>Creating a quality management program / Richard P. Dutton<br/>Health information technology use for quality assurance and improvement / Christine Doyle<br/>Safety in remote locations / Samuel Grodofsky, Meghan Lane-Fall, and Mark S. Weiss<br/>Medication safety / Alan F. Merry<br/>Operating room fires and electrical safety / Stephan Cohn and P. Alan Klock Jr<br/>Disruptive behavior : the imperative for awareness and action / Sheri A. Keitz and David J. Birnbach<br/>Managing adverse events : the aftermath and the second victim effect / Sven Staender.

::Summary## This book provides a roadmap for optimizing quality and safety within radiology practices, whether academic or private and irrespective of their national setting. All aspects of the radiology workflow are addressed, from imaging appropriateness, examination scheduling, and patient preparation through to imaging protocol optimization (including radiation dose management), modality operations, reporting (including structured reporting), and report communication. The book highlights innovative IT tools, including clinical decision support, that drive compliance with national best practice standards and guidelines. The use of big data tools to manage and enhance clinical delivery is addressed. Finally, metrics designed to measure the value that radiology brings to patient care and patient outcomes are introduced. Readers wishing to deepen their understanding of contemporary best practices regarding quality and safety will find this book to be a rich source of practical information.

::Contents##<br/>1. The many perspectives of quality and safety in neurosurgery<br/>2. The history and future of quality and safety in neurosurgery<br/>3. Clinical research in quality improvement: complementary approaches to improving neurosurgical practice<br/>4. On developing the tools and metrics for a neurosurgical quality program<br/>5. The role of clinical registries in health care<br/>6. Measuring value of health care: the importance and challenges of measuring true cost<br/>7. Teams, competence, and safety in surgery<br/>8. Evidence-based practice of neurosurgery: implications for quality and safety<br/>9. The physician handoff and its role in quality and safety<br/>10. Improving operating room safety<br/>11. Using multicenter clinical registries to improve outcomes<br/>12. Improving efficiency and mapping surgical procedures using lean methods<br/>13. Quality efforts for reducing mortality in neurosurgery<br/>14. Reducing readmissions<br/>15. Improving outcomes: big data and predictive analytics<br/>16. Improving performance by improving education<br/>17. Improving outcomes with subspecialization and regionalization<br/>18. Quality of care and outcomes in pediatric neurosurgery: incorporating evidence-based practice<br/>19. Eliminating unneccessary diagnostic imaging and labs<br/>20. Creating national practice standards through collaboration<br/>21. Use of risk model for assessment of resident perception of surgical complexity and evaluation of procedural competence<br/>22. Use of physical education and nutrition program to improve outcomes.

::Summary## Drawing on the universal values in health care, the second edition of Quality and Safety in Nursing continues to devote itself to the nursing community and explores their role in improving quality of care and patient safety.<br/>::Contents##<br/>Quality and safety : an overview. Driving forces for quality and safety : changing mindsets to improve health care / Gwen Sherwood ; Policy implications driving national quality and safety initiatives / Mary Jean Schumann ; A national initiative : quality and safety education for nurses / Linda R. Cronewett and Jane Barnsteiner<br/>Quality and safety competencies : the quality and safety education for nurses project. Patient-centered care / Mary K. Walton and Jane Barnsteiner ; Teamwork and collaboration / Joanne Disch ; Quality improvement / Jean Jonson ; Evidence-based practice / Mary Fran Tracy and Jane Barnsteiner ; Safety / Jane Barnsteienr ; Informatics / Thomas R. Clancy and Judith J. Warren<br/>Strategies to build a culture of quality and safety. Transforming education to transform practice : integrating quality and safety in subject-centered classrooms using unfolding case studies / Lisa Day and Gwen Sherwood ; Using narrative pedagogy to foster quality and safety / Pamela M. Ironside, Elizabeth Cerbie Brown and Amy Hagedom Wonder ; Integrating quality and safety competencies in simulation / Kathryn R. Alden and Carol F. Durham ; Quality and safety education in clinical learning environments / Lisa Day and Gwen Sherwood ; Interprofessional approaches to quality and safety education / Mary A. Dolansky, Ellen Luebbers and Shirley M. Moore ; Improving quality and safety with transition-to-practice programs / Nancy Spector, Beth T. Ulrich and Jane Barnsteiner ; Leadership to create change / Joanne Disch ; Global perspectives on quality and safety / Gwen Sherwood<br/>Appendix A: prelicensure competencies<br/>Appendix B: Quality and safety education for nurses graduate/advanced practice nursing competencies<br/>Appendix C: Quality and safety education for nurses : results of a national Delphi study to developmentally level KSAs.

::Summary## Designed for all providers of women's healthcare - including those undertaking Maintenance of Certification programs, trainees preparing for postgraduate examinations, and those initiating or growing a program of quality improvement and patient safety - this practical manual guides those implementing QI and safety programs with specific emphasis on Obstetrics and Gynecology practice. The content contains a strong case-based element to improve accessibility and understanding. An introductory section covers core attributes needed by all physicians to build a culture of patient safety, including leadership, communication and QI skills. Core clinical skills are then reviewed - in a variety of labor ward, office, operating room, and outpatient settings. Finally systems implications are highlighted, including information transparency and disclosure, training programs, and regulatory and legal implications. The editors are involved with national and international initiatives educating physicians in safety aspects of practice. The book is published in collaboration with the Foundation for EXXcellence.<br/>::Contents##<br/>Office safety / Ty B. Erickson and Amber D. Masse<br/>Electronic fetal monitoring and patient safety / David Miller<br/>Patient safety in the outpatient setting / Roger Smith and Mark D. Pearlman<br/>Principles for the safe use of electrosurgery / Fidel A. Valea<br/>The obstetric-gynecologic hospitalist / Christopher C. Swain and Alan M. Dulit<br/>Transparency and disclosure / Sandra Koch<br/>Surgical checklists / John Wachtel and Abraham Lichtmacher<br/>What is a high-reliability organization? / Joseph C. Gambone and John P. Keats<br/>Powerful tools for quality improvement / John P. Keats<br/>Simulation and drills / Shad Deering<br/>Rapid response in obstetrics / Allison R. Durica and Elizabeth S. McCuin<br/>Regulatory and legal implications / Mark S. DeFrancesco<br/>Patient safety : a patient's perspective / Pamela K. Scarrow<br/>Safety programs in a community hospital : evidence-based medicine meets the realities of private practice / Holly S. Puritz<br/>Improving perinatal safety in an integrated healthcare system / Hans P. Cassagnol and Harry Mateer<br/>Fatigue and safety / Peter A. Schwartz, James W. Saxton and Maggie M. Finkelstein<br/>Just culture in women's health services / Michael E. Barfield, Margaret Sturdivant, and Karen Frush<br/>Medication safety in obstetrics and gynecology / Roseann Richards and Angela Brenner<br/>Improving patient safety through team training / Christian M. Pettker and Edmund F. Funai<br/>A systems-based approach to shoulder dystocia safety / William A. Grobman<br/>Creating a learning culture : debriefing and root-cause analysis / Nancy Chescheir<br/>Safe patient handoffs / Diana Behling and Bonnie Dattel<br/>Using clinical scenarios to teach patient safety / Dotun Ogunyemi, Bruce B. Ettinger and Steve Rad<br/>Quality and safety in medical education : implementing a curriculum of patient safety and quality improvement in medical education / Dotun Ogunyemi.

::Summary## The ten chapters of this book provide comprehensive coverage of quality issues in environmental sampling, addressing recent developments and research advances together with advice based on the contributing experts' practical experience.<br/>::Contents##<br/>Quality assurance/quality control in environmental field sampling / Chunlong Zhang, Jochen F. Mueller & Munro R. Mortimer<br/>An introduction to quality assurance/quality control in environmental sampling / Munro R. Mortimer & Jochen F. Mueller<br/>Sampling error and measurement uncertainty / Michael H. Ramsey<br/>Environmental sampling strategy and design / Mark Shibata & Natasha Hausmann<br/>Quality assurance/quality control in surface water sampling / Jianying Zhang & Chunlong Zhang<br/>Quality assurance/quality control in stormwater sampling / David McCarthy & Daren Harmel<br/>Quality assurance/quality control in groundwater sampling / Valérie Guérin, Stéphane Roy & Jean-Philippe Ghestem<br/>Quality assurance/quality control in wastewater sampling / Christoph Ort<br/>Quality assurance/quality control for monitoring mine-generated wastewaters / Ross E.W. Smith<br/>Quality assurance/quality control in air sampling / Richard Rago<br/>Quality assurance/quality control in biological sampling / Anders Bignert<br/>Index.

::Summary## This book is a comprehensive and timely compilation of strategy, methods, and implementation of a proof of concept modified quality module of Good Laboratory Practices (GLP). This text provides a historical overview of GLP and related standards of quality assurance practices in clinical testing laboratories as well as basic research settings. It specifically discusses the need and challenges in audit, documentation, and strategies for its implications in system-dependent productivity striving research laboratories. It also describes the importance of periodic training of study directors as well as the scholars for standardization in research processes. This book describes different documents required at various time points of a successful Ph.D and post-doc tenure along with faculty training besides entire lab establishments. Various other areas including academic social responsibility and quality assurance in the developing world, lab orientations, and communication, digitization in data accuracy, auditability and back traceability have also been discussed. This book will be a preferred source for principal investigators, research scholars, and industrial research centers globally.<br/>::Contents##<br/>1 Historical Overview of Quality Assurance in Biological Research<br/>2 Conceptual framework of research data auditability<br/>3 Management of skilled human resources by Youth Oriented Good Laboratory Practices (YOG)<br/>4 Operationalization of research SOPs for PhD scholars<br/>5 Creating Data Recording Sheets (DRS) in quality management system<br/>6 The value of Master Schedules in benchmarking research productivity<br/>7 Logsheets and the Academic Progress of PhD Students<br/>8 Instigation and adherence to the quality assurance program to avoid academic conflicts<br/>9 Data fraud and essence of data verifiability<br/>10 The role of document control and archiving records in laboratory management<br/>11 Academic Social Responsibility and Quality Assurance in the developing world a framework for implementation<br/>12 Good Laboratory Practices: Lab orientations, meetings and value of communication<br/>13 Role of data digitization on data integrity.

::Summary## Development of superior crops that have consistent performance in quality and in quantity has not received the same emphasis in the field of genetics and breeding as merited. Specialty trait requires special focus to propagate. Yet basic germplasm and breeding methodologies optimized to improve crops are often applied in the development of improved specialty types. However, because of the standards required for specialty traits, methods of development and improvement are usually more complex than those for common commodity crops. The same standards of performance are desired, but the genetics of the specialty traits often impose breeding criteria distinct from those of non-specialty possessing crops. Specifically, quality improvement programs have unique characteristics that require careful handling and monitoring during their development for specific needs. Adding value either via alternative products from the large volumes of grain produced or development of specialty types is of interest to producers and processors. This work assimilates the most topical results about quality improvement with contemporary plant breeding approaches. The objective of this book is to provide a summary of the germplasm, methods of development, and specific problems involved for quality breeding. In total, fourteen chapters, written by leading scientists involved in crop improvement research, provide comprehensive coverage of the major factors impacting specialty crop improvement.<br/>::Contents##<br/>Intro; Foreword; Preface; Contents; Contributors; About the Editors; <br/>Chapter 1: Genomic Interventions for Biofortification of Food Crops; 1.1 Introduction; 1.2 Genetic Variation for Various Micronutrients in Crop Plants; 1.3 The Genetic Structure of Mineral/Nutrient Content in Crop Plants; 1.3.1 Discovery of QTL Controlling Micronutrient Content in Crops; 1.3.2 Association Genetics to Discern Genomic Regions Linked with Mineral Traits; 1.4 Functional Genomics and Grain Micronutrients Accumulation in Crops; 1.5 Transgenic Interventions for Enriching Grain Nutrient Content 1.6 High-Throughput Ionome Profiling and Biofortification Breeding1.7 Whole-Genome Predictions for Improving Elemental Concentrations of Crops; 1.8 Conclusion and Perspectives; References; <br/>Chapter 2: Marker-Assisted Breeding for Improving the Cooking and Eating Quality of Rice; 2.1 Introduction; 2.2 Cooking and Eating Properties of Rice; 2.2.1 Apparent Amylose Content; 2.2.2 Genetics of Apparent Amylose Content; 2.2.3 Gelatinization Temperature; 2.2.4 Genetics of Gelatinization Temperature; 2.2.5 Gel Consistency; 2.2.6 Genetics of Gel Consistency; 2.2.7 Paste Viscosity Parameters 2.2.8 Genetics of Paste Viscosity Parameters2.2.9 Aroma; 2.2.10 Inheritance of Aroma; 2.3 DNA Markers Used for Predicting Cooking and Eating Quality in Rice; 2.3.1 Molecular Markers for AAC, RVA and GC; 2.3.2 DNA Markers for GT; 2.3.3 DNA Markers for Aroma in Rice; 2.4 Application of Molecular Markers for Rice Breeding in the Last Two Decades; 2.4.1 Examples of Marker-Assisted Breeding for Cooking and Eating Quality in Rice; 2.4.2 Modern Markers Technologies for Breeding for Rice Grain Quality and Other Traits; 2.5 Conclusions; References 3.6.1 Variation in Mineral Content Among Potato Cultivars and in Germplasm Collections3.6.2 Genetic Biofortification of Iron and Zinc; 3.6.3 Agronomic Biofortification of Zinc; 3.6.4 Significance of Calcium; 3.7 Vitamin Biofortification; 3.7.1 Vitamins B9 (Folate) and B1 (Thiamin); 3.7.2 Vitamins C (Ascorbic Acid), B3 (Niacin), B5 (Pantothenic Acid) and B6 (Pyridoxine); 3.8 Phenolic Acids, Anthocyanins and Carotenoids; 3.8.1 Anthocyanins; 3.8.2 Carotenoids; 3.8.3 Genetic Engineering of Carotenoids; References <br/>Chapter 3: Improving the Nutritional Value of Potatoes by Conventional Breeding and Genetic Modification3.1 Introduction; 3.2 Evolution of Modern Potatoes and Breeding Methods; 3.2.1 Domestication in South America; 3.2.2 South America to the World; 3.2.3 Conventional Breeding Methods; 3.2.4 Genetic Modification Methods; 3.3 Problems Ancient and Modern; 3.3.1 Domestication and Glycoalkaloids; 3.3.2 Frying and Acrylamide; 3.4 Resistant Starch and Glycaemic Index; 3.5 Protein Content and Amino Acid Balance; 3.6 Mineral Biofortification

::Contents##<br/>1 Challenges and Opportunities for Biotech Quality by Design<br/>2 Lessons Learned From Monoclonal Antibody Applications to the Office of Biotechnology Products Quality by Design Pilot Program<br/>3 Definitions and Scope of Key Elements of QbD<br/>4 An Overview of Quality by Design for Drug Product<br/>5 Development of Drug Product Formulations: Molecular Design and Early Candidates Screening<br/>6 Approaches for Early Developability Assessment of Proteins to Guide Quality by Design of Liquid Formulations<br/>7 Application of QbD Principles to Late-stage Formulation Development for Biological Liquid Products<br/>8 Application of QbD Principles for Lyophilized Formulation Development<br/>9 Drug Substance Frozen Storage and Thawing<br/>10 Quality by Design as Applied to Drug Substance Formulation using Ultrafiltration and Diafiltration<br/>11 A QbD Approach in the Development and Scale-up of Mixing Processes<br/>12 Application of QbD Elements in the Development and Scale-up of a Commercial Filtration Process<br/>13 Application of QbD Elements in the Development and Scale-up of Commercial Filling Process<br/>14 Lyophilization Process Design and Development Using QbD Principles<br/>15 Visible and Subvisible Protein Particle Inspection Within a QbD-based Strategy<br/>16 Quality by Design for Distribution of Environmentally Sensitive Pharmaceutical Products<br/>17 Quality by Design for Primary Container Components<br/>18 Devices and Combination Products for Biopharmaceuticals<br/>19 Applicability of QbD for Vaccine Drug Product Development<br/>20 Automation and High Throughput Technologies in Biopharmaceutical Drug Product Development with QbD Approaches<br/>21 Critical Quality Attributes, Specifications, and Control Strategy<br/>22 Multivariate Analysis for Process Understanding, Monitoring, Control and Optimization in Lyophilization Processes<br/>23 Using Mathematical Modeling and Prior Knowledge for QbD in Freeze-drying Processes<br/>24 Application of Multivariate Statistical Process Monitoring to Lyophilization Process<br/>25 Application of PAT in Real-time Monitoring and Controlling of Lyophilization Process<br/>26 Product Homogeneity Assessment during Validation of Biopharmaceutical Drug Product Manufacturing Processes<br/>27 Application of Quality by Design Principles to the Drug Product Technology Transfer Process<br/>28 Regulatory Considerations For Implementation of the QbD Paradigm for Biologics: Laying the Foundation for Product and Process Lifecycle Management.

::Summary## This book follows the continuum of cancer care model as its outline vide infra. As cancer is now a very multidisciplinary disease, it encourages dedicated professionals from various specialties as well as active patient cooperation in order to improve successful treatment and survival. This text will serve as a detailed reference source for healthcare providers intending to improve the quality of survivorship of cancer patients, as well as help create affordable care plans. Initially it discusses the current cancer care crisis on a global and then national platform. Chapters include discussions about disability adjusted life years lost, lost productivity, loss of life and its impact upon the nation and communities. In order to deescalate the financial impact of cancer on society and government, this text incorporates smarter and efficient treatment alternatives that will also improve the survivorship of patients, families and caregivers. It also illustrates how prevention and screening programs can be incorporated to improve cancer care. Quality Cancer Care: Survivorship Before, During and After Treatment will become an invaluable resource for healthcare professionals and clinical staff involved in the delivery of cancer care.<br/>::Contents##<br/>Outlining the Crisis in Cancer Care<br/>Public Reporting of Institution and Provider Level Outcomes<br/>Cancer Statistics: Global and National<br/>Understanding the Social Determinants of Cancer: Challenges, Opportunities and Pathways to Success<br/>How Prevention and Screening Programs Can Be Identified Through a Community Health Needs Assessment<br/>The Role of Quality Metrics in Improving Oncologic Survival<br/>Patient Navigation in Cancer Care Delivery<br/>Survivorship<br/>Oncology Rehabilitation<br/>Building a Team to Improve Cancer Survivorship<br/>Integrative Care's Increasing Role<br/>Medical-Legal Partnerships in Cancer Care<br/>Palliative Care for Cancer and Treatment Related Changes for In-Patients<br/>Ambulatory Palliative Care<br/>End-of-Life Care and Cancer: Psychosocial Needs of Patients and the Bereaved<br/>Physician Leadership.

::Summary## This practical, unique textbook provides a foundation for the essential elements of patient safety and quality improvement (QI) for orthopaedic trainees, though the content covered will be of interest to veteran clinicians as well. Currently, there are few existing resources and didactics focused on this crucial yet often overlooked area of medical practice, which makes this the first true textbook on the subject within the field of orthopaedic surgery. Utilizing a user-friendly approach including generous figures, tables, and bulleted key points, the text presents comprehensive background information on QI principles, models, and patient safety. More specifically, it focuses on orthopaedic concerns, such as biologics and implants, registries, checklists, surgical site infection risk reduction, use of evidence-based medicine and care maps, simulation to improve care, and shifting from volume to value, among others. Related topics such as diversity and inclusion, provider wellness strategies, leadership strategies to develop an efficient and safe work culture, and innovation are also presented. Throughout, the aim is to demonstrate that QI is a multidisciplinary goal that can only flourish in an environment of supportive accountability. With contributions by leaders in the field, Quality Improvement and Patient Safety in Orthopaedic Surgery provides trainees and surgeons in the field a valuable and pragmatic toolkit for successful and sustainable clinical practice.<br/>::Contents##<br/>Concepts of Patient Safety<br/>QI Principles and Models<br/>TeamSTEPPS: Strategies and Tools to Enhance Performance and Patient Safety<br/>Shifting from Volume to Value<br/>Quality Improvement: Using Care Pathways in EMR<br/>Pre-op Optimization Checklists<br/>Surgical Site Infection Risk Reduction<br/>Reduction of Wrong Site Surgery<br/>Learning from Mistakes<br/>Use of Registries and Prospective Cohorts to Improve Care<br/>Clinical Practice Guidelines and Appropriate Use Criteria to Guide Care<br/>Performance Measures<br/>Interpreting and Implementing Evidence for Quality Research<br/>Biologics, Implants, and Patient Safety<br/>Device Industry: Preventing, Identifying and Mitigating Problems<br/>Variation, Costs and Physician behavior<br/>Development of Care Maps for Complex Conditions<br/>Communication Strategies to Minimize Harm and Improve Care in Orthopaedic Surgery<br/>Integration of Physician Management into Supply Chain optimization<br/>Organizational Response to Errors<br/>Using Simulation to Decrease Patient Harm<br/>Safe and Effective Alleviation of Pain and Optimal Opioid Stewardship<br/>Diversity and Cultural Competence to enhance Quality and Safety<br/>Radiation Safety<br/>Physician and Clinician Well-Being<br/>Advocacy to promote quality musculoskeletal care<br/>The Role of the Board in Driving Performance Improvement<br/>Innovation and Value<br/>The Modern Orthopaedic Morbidity and Mortality Conference: An Instrument for Education and System-wide Quality Improvement<br/>Telehealth and Quality Care<br/>Using Quality Improvement to Enhance Geriatric Fracture Care<br/>Orthopaedic Surgeons as Managers and Leaders: Developing the Right Culture.

::Summary## This comprehensive textbook provides a state of the art overview of the means by which quality in patient care is ensured within the field of nuclear medicine. Acknowledged experts in the field cover both management aspects, such as laws, standards, guidelines, patient safety, management instruments, and organisations, and specific issues, including radiation safety and equipment. Quality in Nuclear Medicine not only presents detailed information on the topics discussed but should also stimulate further discussion and offer an important tool to all professionals in the field of nuclear medicine and their stakeholders. Readers will find that the book provides a wealth of excellent guidance and reflects the pioneering role of nuclear medicine in advancing different aspects of quality within medicine.<br/>::Contents##<br/>Part 1 Laws, standard and guidelines: From ISO to ISO HealthCare<br/>Good Clinical Practice (GCP)-ICH and scientific integrity<br/>Good Manufacturing Practice (GMP)/Farmacopee<br/>Relation between different societies in relation to guidelines (Dutch Society of Nuclear Medicine, EANM, SNM)<br/>KEW/Euratom (in Europe and internationally)<br/>Wet op de dierproeven (internationally)<br/>International laws (e.g. Registration laws of clinicians, farmacists etc)<br/>Privacy laws<br/>Contract research and investigator driven research<br/>Part 2 Radiation safety: Environment<br/>Personnel and public people<br/>Patients<br/>Waste management/Decommissioning of the cyclotron<br/>Terroristic threats<br/>Part 3: Equipment: Medical devices<br/>PET/CT and image quality<br/>PET/MRI<br/>Micro SPECT/PET<br/>Standardization<br/>Service quality, periodic measurements<br/>Annotations<br/>Data management/ computer aided diagnostics/Expert systems<br/>Part 4: Management instruments : EFQM<br/>VMS<br/>HTA/HFMEA/Risk management systems<br/>Quality controls of cameras<br/>Quality aspects in daily management in nuclear medicine<br/>No shows with particular emphasis on nuclear medicine<br/>Part 5: Organisations: Medical Ethical Committees and nuclear medicine<br/>Animal Ethical Committees and nuclear medicine<br/>Quality visits<br/>the Dutch example (Dutch Society of Nuclear Medicine)<br/>Quality visits<br/>the EANM example<br/>Quality visits<br/>the SNM example<br/>IAEA<br/>training<br/>School for Nuclear Medicine<br/>teaching.

::Summary## This book reviews quality definition, measurement, improvement, value, and accountability for obesity management. The interplay between quality, cost, access and satisfaction is fully depicted with a goal toward not only fulfilling current standards but also anticipating future needs. A thorough inventory of current best practices in all aspects of obesity care is cataloged with a gap analysis also employed for potential areas of improvement to be road mapped. All chapters are written by experts in their fields and include the most up-to-date scientific and clinical information, take home messages, and questions towards following the requirements of quality certification in obesity management. Quality in Obesity Treatment provides a comprehensive, contemporary review of this field and serves as a valuable resource for Bariatric Surgeons, Primary Care Physicians, Policy Makers, Insurance Administrators, Bariatricians, and any medical specialty interested in obesity quality management with likely candidates coming from GI, endocrinology, cardiology, sleep medicine and orthopedics.<br/>::Contents##<br/>Intro; Preface; Contents; Contributors; Part I: National Definitions, Goals, Initiatives;<br/> 1: Defining and Measuring Quality; Why Measure Quality?; What Is Quality?; How Do You Measure Quality?; Measuring Quality in Metabolic and Bariatric Surgery; Surgeons Should Lead in Measuring Quality; References;<br/> 2: Building a Metabolic and Bariatric Surgery Data Registry: Quality Improvement Through Measurement; Introduction; History and Timeline of Quality Improvement; The History of Surgical Innovation in Metabolic and Bariatric Surgery; The Journey Toward Bariatric Surgery Accreditation Limitations of the Original Metabolic and Bariatric Surgery Accreditation ProgramsThe New Era in Metabolic and Bariatric Surgery Quality Improvement: The Metabolic and Bariatric Surgery Accreditation and Quality Improvement Program (MBSAQIP); Conclusion; References;<br/> 3: Lessons Learned from ACS NSQIP; Origins and Early Development; Logistics and Feedback Mechanisms; Demonstration of Local Quality Improvement; Powerful Quality Research Platform; Future Directions: Increasing Breadth and Depth of Data; Lessons for Growing Quality Improvement Programs; References<br/> 4: The Institute of Medicine and the Pursuit of QualityIntroduction; To Err Is Human; Crossing the Quality Chasm; The Ongoing Pursuit of Quality; References;<br/> 5: Private Payer Initiatives for Quality Improvement; Introduction; Health-Care Quality in the United States; Top-Down Approaches to Quality Improvement; Collaborative Quality Improvement; Elements of Collaborative Quality Improvement; Benefits of Collaborative Quality Improvement; Collaborative Quality Improvement in Surgery; Northern New England Cardiovascular Disease Study Group; Surgical Care and Outcomes Assessment Program Payer-Funded Collaborative Quality ImprovementPay for Participation; Michigan Bariatric Surgery Collaborative; Opportunities and Challenges; Conclusion; References;<br/> 6: The Value Proposition and ProvenCare®; Geisinger Health System and Value Reengineering; The Development of ProvenCare® Bariatrics; Analysis of the Impact of ProvenCare® Bariatrics; Reliability; Length of Stay (LOS); Postoperative Complications; Additional Outcomes; Efficacy of the ProvenCare® Bariatric Program; Financial Analysis; ProvenCare® Bariatric and the Value Proposition; Reliability; Quality; Costs "Unjustified" VariabilityConclusions; References;<br/> 7: Patient Satisfaction, Patient-Reported Outcomes, and Quality; Introduction; PROs and PROMs: An Overview; Patient Experience; HCAHPS; CG-CAHPS; S-CAHPS; Recovery; Quality of Life; Functional Status; PROMs in the MBSAQIP: The LOBSTER PROMs Project; Conclusion; References;<br/> 8: Understanding Risk and Reliability Adjustment in Metabolic and Bariatric Surgical Quality Profiling; Introduction; Measuring Surgical Quality; Risk Adjustment; Risk Adjustment with Logistic Regression Models; Estimating the Effect of a Predictor Determining the Significance of a Predictor

::Summary## This open access book provides a concise yet comprehensive overview on how to build a quality management program for hematopoietic stem cell transplantation (HSCT) and cellular therapy. The text reviews all the essential steps and elements necessary for establishing a quality management program and achieving accreditation in HSCT and cellular therapy. Specific areas of focus include document development and implementation, audits and validation, performance measurement, writing a quality management plan, the accreditation process, data management, and maintaining a quality management program. Written by experts in the field, Quality Management and Accreditation in Hematopoietic Stem Cell Transplantation and Cellular Therapy: A Practical Guide is a valuable resource for physicians, healthcare professionals, and laboratory staff involved in the creation and maintenance of a state-of-the-art HSCT and cellular therapy program.<br/>::Contents##<br/>Overview of Quality Management and Accreditation in Hematopoietic Stem Cell Transplantation and Cellular Therapy<br/>Development of Organizational Quality Management Program<br/>Document Development, Implementation, Review and Archive<br/>Audits<br/>Qualification and Validation<br/>Outcome Analysis<br/>Personnel Requirements Including Job Descriptions<br/>Third-Party Agreements<br/>Performance Measurement<br/>Tracking and Traceability<br/>Adverse Events and Corrective Preventative Actions<br/>Process Indicators<br/>Writing Quality Management Plan<br/>The Accreditation Process<br/>Data Management<br/>Maintaining the Quality Management Program<br/>Training Programme<br/>Risk Management.

::Summary## "Quality Management in Anatomic Pathology: Strategies for Assessment, Improvement, and Assurance is the only comprehensive manual designed to improve patient care while ensuring your laboratory achieves its accreditation standards. It provides pathologists and lab directors with the tools necessary to develop, implement, and maintain a comprehensive quality program, with an emphasis on regulatory compliance and cross-references to the CAP Laboratory Accreditation Program checklists, Joint Commission standards, and CLIA ’88. Contents include general approaches to quality management, including designing a plan, defining and preventing errors, and plan components and monitors; systematic approaches to quality assurance in histology, intraoperative consultation, cytopathology, autopsy, immunohistochemistry, and molecular pathology; informatics, ISO 15189, and specimen tracking systems; and damage control and legal issues."-- Provided by publisher.

::Summary## In the last decades, major advances have been made in assisted reproductive technologies (ART) and the public demand for these procedures has increased globally. All ART clinics, from those just starting out to the well established, must employ the latest equipment and implement the best practices, while ensuring that their resources are effectively engaged to optimize patient outcomes. This is a tenet of the fiduciary role of physicians and it is increasingly recognized as a quantifiable goal regulated by formal certifications and accreditations. Quality management protocols such as those proposed by the International Organization for Standardization (ISO) are being rapidly adopted as standards of measure. Quality Management in ART Clinics: A Practical Guide provides easily adoptable ways to implement and improve formalized quality management systems. Essential to any clinic to achieve best practices and maintenance of formal regulatory certifications, this book brings together the know-how of experienced opinion leaders operating in key areas worldwide. The book offers an overview of primary regulations in the ART field, with attention to quality management demands, and links specific requirements to practical steps for implementation. Filled with process and procedure examples, flow diagrams and administrative form templates, this book is the first of its kind, gathering the necessary elements for optimizing practice, management, and quality assurance.<br/>::Contents##<br/>Part 1. Establishing a Quality Management System<br/>Introduction to Quality Management in ART Clinics<br/>Quality Management Systems<br/>Where to Start<br/>Defining Processes and Procedures<br/>Training Personnel<br/>How To Get Information<br/>Part 2. Reproductive Laboratories<br/>The Role of Reproductive Laboratories in the ART Clinic<br/>Defining What Reproductive Laboratories Do<br/>Explaining How Reproductive Laboratories Work<br/>Ensuring that Reproductive Laboratories Provide High-Quality Services<br/>Part 3. International Experience<br/>Singapore<br/>India<br/>South Africa: A Laboratory Perspective on Quality Control<br/>Nigeria: Experience with Quality Management and IVF in a Developing Country<br/>Gulf Countries<br/>United States of America<br/>Chile<br/>Brazil<br/>Belgium: ISO 9001:2000 Certification as a Base for Total Quality Management in ART<br/>The Netherlands<br/>Australia: QMS in IVF Centres.

::Summary## In recent years, the attention of the scientific and social community has not solely been on producing new findings, but increasingly also on the related issues of the reliability, safety, and efficacy of the discoveries made, as well as the efficient and effective use of resources. The adoption of management models and tools can help scientists to improve their research, ensuring valuable, robust and dependable outcomes. Quality disciplines have been widely used for decades in industrial and business fields, building a knowledge base that can be translated and exploited, much to the advantage of scientific research. However, quality references in scientific research are still extremely rare and largely limited to an international guideline and a few sector-specific standards. Despite WHO and EU Commission campaigns, there are still precious few practical texts that offer researchers guidance on quality principles and provide simple tools and methodologies for their daily work. The book, starting from the problem of the reproducibility of scientific results and the substantial contribution that the Quality approach can make to research (Chapter 1), introduces the reader to key principles and basic concepts of Quality and illustrates both general and research-specific quality standards, paving the way for further discussion (Chapter 2). In turn, Chapter 3 presents detailed applications of Quality principles in various aspects of research, from study and ethics to materials and equipment management. Chapters 4 and 5, respectively, are devoted to Quality tools and Quality methodologies, as well as soft skills, all of which are valuable to scientific experimentation and study management. The concepts and practical tools discussed are extensively illustrated with examples from actual applications in scientific research.<br/>::Contents##<br/>Intro; Foreword; Contents; Abbreviations;<br/> 1: Introduction; 1.1 Acknowledgements; 1.2 Permissions; References;<br/> 2: How Quality Can Improve Reproducibility; 2.1 The Unknown of Reproducibility; 2.1.1 Irreproducibility and Retractions; 2.1.2 The Economics of Poor Reproducibility; 2.1.3 Reasons and Solutions; 2.2 What Is Quality; 2.3 Quality for Research; 2.4 Research Integrity; References;<br/> 3: Principles, References and Standards; 3.1 Quality Basics; 3.2 Total Quality Management; 3.2.1 The Process Approach; 3.2.2 Principles; 3.2.3 PDCA Cycle; 3.2.4 The Requirements. 3.3 Quality Certification and Accreditation3.4 Quality Standards for Certification in Scientific Research; 3.4.1 ISO 9000; 3.4.2 Good Laboratory Practice; 3.4.3 ISO/IEC 17025; 3.4.4 Other References; References;<br/> 4: Quality and Basic Biomedical Research; 4.1 What Is Basic Biomedical Research; 4.2 Conscious Management; 4.3 Quality Throughout the Research Project; 4.3.1 Management of Study Contents and Controls; 4.3.1.1 Initial Requirements; 4.3.1.2 Controls and Metrics; 4.3.1.3 Documentation; 4.3.1.4 Training; 4.3.1.5 Communication; 4.3.1.6 Procurement. 4.3.2 Management of the Research Project4.3.2.1 Planning; 4.3.2.2 Executing and Measuring; 4.3.2.3 Exploiting; 4.3.2.4 The Importance of Planned Controls (Shannon Eaker); 4.4 International References and Models; 4.4.1 WHO-TDR Handbook on Quality Practices in Basic Biomedical Research; 4.4.2 Joint Code of Practice for Research: JCoPR (UK); 4.4.3 Research Quality Association Handbook and Guidelines; 4.4.4 Other Examples; 4.5 Quality Management in Basic Biomedical Research; 4.5.1 Organisation; 4.5.1.1 Quality Policy and Objectives; 4.5.1.2 Organisational Chart and Job Description. 4.5.2 Quality System4.5.2.1 Quality Assurance and Quality Control; 4.5.2.2 Research Reviews; 4.5.3 Personnel; 4.5.3.1 Responsibility; 4.5.3.2 Competence, Skills and Motivation; 4.5.4 Physical Resources; 4.5.4.1 Economics; 4.5.4.2 Facilities; 4.5.4.3 Equipment; 4.5.4.4 Products for the Research; 4.5.4.5 Computer Systems; 4.5.5 Validation; 4.5.5.1 Protocols and Assay Validation; 4.5.5.2 Result Validation; 4.5.6 Documentation; 4.5.6.1 Prescriptive Documents; 4.5.6.2 Descriptive Documents; 4.5.6.3 Study Report; 4.5.7 Storage and Archiving; 4.5.7.1 Data Archiving. 4.5.7.2 Sample Storage4.5.8 Health and Safety; 4.5.9 Publishing Practices; 4.5.10 Ethics; 4.6 Examples of Application; 4.6.1 Managing Research Resources in a Large Institute: The San Raffaele Experience (Daniele Zacchetti); 4.6.2 A QMS for a Life Sciences Research Laboratory and Its Related Management Software (the qPMO WP3 Team); 4.6.3 GLP as a Reference for Non-regulated Research (the MoBiLab Team); References;<br/> 5: Quality Tools for the Scientific Research; 5.1 Tools for Project and Process Quality; 5.2 7 Basic Tools of TQM; 5.2.1 Pareto Chart.

::Summary## While the healthcare system continues to shift towards more emphasis on quality metrics, there remains a substantial gap between the expectations of healthcare policies and standards of hospital administrations vs. the realistic care provided by the average healthcare provider. This book offers the perspective of the healthcare provider and aims to fulfill the unmet need to educate other healthcare providers on recognizing quality measures and understanding how to achieve them to meet standards of quality care. This book covers the historical perspective of quality measures, the context of their existence, their utility, and the contemporary issues related to their use. Simultaneously, it critically addresses the quality of these quality metrics and presents the evidence available to date on the efficacy and the limitations of these quality measures. This text is all-inclusive and is organized into chapters that include the evolution of quality metrics in healthcare, the practical role of hospitals, as well as the practical role of individual healthcare providers in addressing quality metrics. The chapters also include assessment of quality metrics that uniquely pertain to medical and surgical practices, as well as non-clinical quality metrics that specifically target undergraduate and graduate medical training. Finally, the book reflects on the use of contemporary quality metrics and their impact on outcomes, patient care, and public health and policy making. In these chapters, tables and illustrations, including algorithms, will be used to provide systematic approaches to common issues related to quality metrics. In addition, historical anecdotes and case presentations will be used to address pearls in contemporary practice of quality metrics. Quality Measures is the definitive reference on quality metrics in healthcare and is a valuable resource for healthcare providers, trainees, administrators and public health agencies.<br/>::Contents##<br/>1. The History of Medical Quality Metrics<br/>2. Pediatric Quality Measures<br/>3. Quality and Safety Improvement in Surgery<br/>4. Infection Prevention Quality Metrics<br/>5. Evolution of Modern Cardiovascular Quality Metrics<br/>6. Along the Road to Quality in Cancer Care<br/>7. Quality Measures for Palliative Care<br/>8. Developing a Hospital Quality Metrics System and Dashboard<br/>9. Patient Satisfaction Metrics<br/>10. Quality Measures in Undergraduate Medical Education<br/>11. Resident Quality Training: More than Metrics<br/>12. The Role of Hospital Board of Trustees in Ensuring Quality Care<br/>13. Quality Improvement and Population Management in Adult Primary Care<br/>14. Quality of Quality Measures.

::Contents##<br/>Principles of measurement scales<br/>Developing a questionnaire<br/>Scores and measurement : validity, reliability, sensibility<br/>Multi-item scales<br/>Factor analysis and structural equation modelling<br/>Item response theory and differential item functioning<br/>Item banks, item linking, and computer-adaptive tests<br/>Choosing and scoring questionnaires<br/>Clinical trials<br/>Samples sizes<br/>Cross-sectional analysis<br/>Exploring longitudinal data<br/>Modelling longitudinal data<br/>Missing data<br/>Practical and reporting issues<br/>Death and quality-adjusted survival<br/>Clinical interpretation<br/>Biased reporting and response shift<br/>Meta-analysis.

::Summary## This book explores the meaning of quality of life in care for older persons and introduces the reader to their main concerns when receiving care. Based on qualitative research, it pays particular attention to the needs and requirements of older people, considering their individual family situations, social circumstances, values and lifestyles. Person-centred care is a way of providing nursing care that puts older people and their families at the core of all decisions, seeing each person as an individual, and working together to develop appropriate solutions. Following an introduction to the concept of quality of life in old age, the book reviews essential findings from worldwide research into the experiences of older people with regard to nursing care and the impact of these experiences on their quality of life. It investigates health promotion, care provided in nursing homes and assisted living facilities, and palliative care. Each chapter includes a brief introduction to the respective field of nursing care and the problems it has to deal with, concluding with a discussion of their implications for nursing practice in the respective field of care. In closing, the evidence from qualitative research is discussed in relation to current gerontological theories.<br/>::Contents##<br/>Introduction<br/>Quality of life in old age. Theoretical Perspective<br/>Quality of Life: The perspective of community-dwelling older adults<br/>Health promotion and quality of life in old age<br/>Quality of Life in Long-term Care Facilities<br/>Quality of Life in the Process of Dying<br/>Person-centred care and quality of Life.

::Summary## This book introduces a multidimensional system that evaluates quality of life in China by pursuing a quantitative and analytical approach. A host of factors, including economic conditions and individual wellbeing, can affect peoples satisfaction with their lives. In addition to GDP-associated indicators, sociological and environmental factors are also relevant when it comes to evaluating quality of life. Providing a general framework, while also considering gender, education and geographical differences in assessing quality of life, the book offers policy suggestions for improving both individual quality of life and the health of society as a whole.<br/>::Contents##<br/>Introduction: Step Forward to the Stage of Emphasizing Life Quality<br/>Classification of Individual Consumption and Life Quality<br/>The Quality of Employment and Job and its influence factors<br/>Education, Social Mobility and the Quality of Life<br/>Housing Conditions of Urban and Rural Residents and housing inequality<br/>Middle-income Group and Olive-shaped Society<br/>Workers with Urban Household and the Income Gaps of Migrant Workers<br/>Government evaluation on New Generation Youth and Internet Use<br/>Environmental Awareness and Life Quality<br/>The Impact of Medical Treatment on Gender differences in the sense of happiness<br/>Social Trusts and Social Supports<br/>Social Involvement and the Quality of Life<br/>Residents Satisfaction to Life and its Factors<br/>The Sense of Residents Happiness and Spatial Layout<br/>Value Judgment on "Good Society" and Social Cognition<br/>References.

::Summary## Part I. Historical Aspects -- 1. Historical Aspects of Quality in Healthcare -- 2. Quality and Standardization of Medical Education -- 3. The History of Quality Assessment in Spine Care -- Part II. Methodology in Quality Assessment -- 4. Choice of Quality Metrics for Assessment of the Spine Patient -- 5. Patient-Reported Outcomes -- 6. Registries in Spine Care in the United States -- 7. Registries in Spine Care: UK and Europe -- 8. Concepts of Risk Stratification in Measurement and Delivery of Quality -- 9. Risk Adjustment Methodologies -- Part III. Healthcare Systems -- 10. Healthcare Systems in the United States -- 11. The National Health Service (NHS) in England: Trying to Achieve Value-Based Healthcare -- 12. Quality Spine Care in Australasia -- 13. Healthcare Systems: India -- 14. Healthcare Systems and Quality Assessment of Spine Care in Japan -- 15. Overview of Healthcare System in China -- Part IV. Implementation of Quality Reporting -- 16. Conditions of Care and Episode Groups -- 17. Aligning Healthcare Systems -- 18. Building Quality Metrics into a Practice -- 19. Impact of Quality Assessment on Clinical Practice, Intermountain Healthcare -- 20. Impact of Quality Assessment on Clinical Practice, Kaiser Permanente -- 21. How Quality is Assessed in Insurance Markets -- 22. Centers of Excellence and Payer-Defined Quality Assessment -- 23. Reporting Quality Results -- 24. Achieving Success in Quality Reporting.

::Summary## This book provides a comprehensive survey of the pharmacokinetic models used for the quantitative interpretation of contrast-enhanced imaging. It discusses all the available imaging technologies and the problems related to the calibration of the imaging system and accuracy of the estimated physiological parameters. Enhancing imaging modalities using contrast agents has opened up new opportunities for going beyond morphological information and enabling minimally invasive assessment of tissue and organ functionality down to the molecular level. In combination with mathematical modeling of the contrast agent kinetics, contrast- enhanced imaging has the potential to provide clinically valuable additional information by estimating quantitative physiological parameters. The book presents the broad spectrum of diagnostic possibilities provided by quantitative contrast-enhanced imaging, with a particular focus on cardiology and oncology, as well as novel developments in the area of quantitative molecular imaging along with their potential clinical applications. Given the variety of available techniques, the choice of the appropriate imaging modality and the most suitable pharmacokinetic model is often challenging. As such, the book provides a valuable technical guide for researchers, clinical scientists, and experts in the field who wish to better understand and properly apply tracer-kinetic modeling for quantitative contrast-enhanced imaging.<br/>::Contents##<br/>Introduction to contrast-enhanced imaging<br/>Introduction to pharmacokinetic modeling<br/>Intravascular contrast agents (UCA, blood-pool MRI)<br/>Extravascular contrast agents (MRI, CT, nanodroplets)<br/>Molecular/targeted contrast agents (nuclear imaging and tUCA).

::Summary## This open access book presents the rise of technology-enabled methods and tools for objective, quantitative assessment of Quality of Life (QoL), while following the WHOQOL model. It is an in-depth resource describing and examining state-of-the-art, minimally obtrusive, ubiquitous technologies. Highlighting the required factors for adoption and scaling of technology-enabled methods and tools for QoL assessment, it also describes how these technologies can be leveraged for behavior change, disease prevention, health management and long-term QoL enhancement in populations at large. Quantifying Quality of Life: Incorporating Daily Life into Medicine fills a gap in the field of QoL by providing assessment methods, techniques and tools. These assessments differ from the current methods that are now mostly infrequent, subjective, qualitative, memory-based, context-poor and sparse. Therefore, it is an ideal resource for physicians, physicians in training, software and hardware developers, computer scientists, data scientists, behavioural scientists, entrepreneurs, healthcare leaders and administrators who are seeking an up-to-date resource on this subject.<br/>::Contents##<br/>Introduction to Quality of Life and WHOQOL model<br/>Physical health: Activities of daily living<br/>Physical health: Dependence on medicinal substances and medical<br/>Physical health: Energy and Fatigue<br/>Physical health: Mobility<br/>Physical health: pain and discomfort<br/>Physical health: sleep and rest<br/>Physical health: work capacity<br/>Psychological: bodily image and appearance<br/>Psychological: negative and positive feelings<br/>Psychological: self-esteem<br/>Psychological: spirituality/religion/personal beliefs<br/>Psychological: thinking, learning, memory and concentration<br/>Social relationships: personal relationships +social support<br/>Social relationships: sexual activity<br/>Environment: financial resources<br/>Environment: freedom, physical safety and security<br/>Environment: health and social care: accessibility and quality<br/>Environment: home environment<br/>Environment: opportunities for acquiring new information and skills<br/>Environment: participation in and opportunities for recreation/leisure activities<br/>Environment: physical environment (pollution, noise, traffic, climate)<br/>Environment: Transport<br/>Future directions.

::Contents##<br/>Philosophy of science and introduction to epidemiology<br/>Routine data sources and descriptive epidemiology<br/>Standardisation<br/>Surveys<br/>Cohort studies<br/>Case-control studies<br/>Intervention studies<br/>Life tables, survival analysis and cox regression<br/>Systematic reviews and meta-analysis<br/>Prevention strategies and evaluation of screening<br/>Probability distributions, hypothesis testing and Bayesian methods.

::Summary## This book presents cutting-edge research on the use of physical and mathematical formalisms to model and quantitatively analyze biological phenomena ranging from microscopic to macroscopic systems. The systems discussed in this compilation cover protein folding pathways, gene regulation in prostate cancer, quorum sensing in bacteria to mathematical and physical descriptions to analyze anomalous diffusion in patchy environments and the physical mechanisms that drive active motion in large sets of particles, both fundamental descriptions that can be applied to different phenomena in biology. All chapters are written by well-known experts on their respective research fields with a vast amount of scientific discussion and references in order the interested reader can pursue a further reading. Given these features, we consider Quantitative Models for Microscopic to Macroscopic Biological Macromolecules and Tissues as an excellent and up-to-date resource and reference for advanced undergraduate students, graduate students and junior researchers interested in the latest developments at the intersection of physics, mathematics, molecular biology, and computational sciences. Such research field, without hesitation, is one of the most interesting, challenging and active of this century and the next.<br/>::Contents##<br/>Diverse protein-folding pathways and functions of beta-hairpins and beta-sheets<br/>MicroRNAs, gene's regulator in prostate cáncer<br/>Subdiffusive Transport in Heterogeneous Patchy Environments<br/>Molecular assembling of the bacterial injectisome: a nanomachine used to inject effector proteins<br/>Pressure-driven DNA denaturation: state of the art and perspectives<br/>In silico identification and gene expression analysis of CDF-like genes from Trichomonas vaginalis in response to Zinc<br/>Dynamical features of a biochemical interaction in a plant root hair cell; a long story short<br/>Homeostasis from a time-series perspective: An intuitive interpretation of the variability of physiological variables<br/>Looking for biomarkers in physiological time series<br/>Systems Biology, Metabolomics and Breast Cancer: Where we are and which is the possible destination in the clinic<br/>Local effective temperatures for the patterns of motion of active particles.

::Contents##<br/>Rationale for Quantitative MRI of the Human Spinal Cord and Clinical Applications<br/>Inflammatory Demyelinating Diseases<br/>Traumatic Spinal Cord Injury: Acute Spinal Cord Injury and Prognosis<br/>Traumatic Spinal Cord Injury: Chronic Spinal Cord Injury and Recovery<br/>Array Coils<br/>Bo Inhomogeneity and Shimming<br/>Susceptibility Artifacts<br/>Ultra-High Field Spinal Cord Imaging<br/>Diffusion-Weighted Imaging of the Spinal Cord<br/>Q-Space Imaging<br/>Advanced Methods to Study White Matter Microstructure<br/>Magnetization Transfer<br/>T₂ Relaxation<br/>Atrophy<br/>Spinal Cord fMRI<br/>Physiological Noise Modeling and Analysis for Spinal Cord fMRI<br/>Mapping the Vasculature of the Spinal Cord --Single Voxel MR Spectroscopy in the Spinal Cord: Technical Challenges and Clinical Applications<br/>Annex: Anatomy of the Spinal Cord.

::Contents##<br/>Twenty years of qPCR: A mature technology?<br/>Minimum information necessary for quantitative real-time PCR experiments<br/>Selection of reliable reference genes for RT-qPCR analysis<br/>Introduction to digital PCR<br/>mRNA and microRNA purity and integrity: The key to success in expression profiling<br/>Mediator probe PCR: Detection of real-time PCR by label-free probes and a universal fluorogenic reporter<br/>Absolute quantification of viral DNA: The quest for perfection<br/>A multiplex real-time PCR-platform integrated into automated extraction method for the rapid detection and measurement of oncogenic HPV type-specific viral DNA load from cervical samples<br/>Real-time PCR detection of mycoplasma pneumoniae in the diagnosis of community-acquired pneumonia<br/>A sensible technique to detect mollicutes impurities in human cells cultured in GMP condition<br/>Real-time quantification assay to monitor BCR-ABL1 transcripts in chronic myeloid leukemia<br/>A reliable assay for rapidly defining transplacental metastasis using quantitative PCR<br/>Circulating cell-free DNA in cancer<br/>Gene expression analysis by qPCR in clinical kidney transplantation<br/>Posttranscriptional regulatory networks: From expression profiling to integrative analysis of mRNA and microRNA data<br/>Clinical applications using digital PCR<br/>Developing noninvasive diagnosis for single-gene disorders: the role of digital PCR.

::Summary## Due to parallel advances in signal processing and computer hardware in the last 15 years, quantitative ultrasound techniques have reached maturity, allowing for the construction of quantitative maps or images of soft tissues. This book will focus on 5 modern research topics related to quantitative ultrasound of soft tissues: - Spectral-based methods for tissue characterization, tissue typing, cancer detection, etc.; - Envelope statistics analysis as a means of quantifying and imaging tissue properties; - Ultrasound elastography for quantifying elastic properties of tissues (several clinical ultrasound scanners now display elastography images); - Scanning acoustic microscopy for forming images of mechanical properties of soft tissues with micron resolution (desktop size scanners are now available); and - Ultrasound computer tomography for breast cancer imaging (new ultrasound tomography systems have been developed and are currently under evaluation clinically).<br/>::Contents##<br/>State of the art methods for estimating the backscatter coefficients<br/>Quantitative Ultrasound History and Successes<br/>Statistics of Scatterer Property Estimates<br/>Attenuation Compensation and Estimation<br/>Quantitative Ultrasound and Cell Death<br/>Modeling of Ultrasound Backscattering by Aggregating Red Blood Cells<br/>Backscatter Quantification for the Detection of Metastatic Regions in Human Lymph Nodes<br/>Quantitative Ultrasound for Tissue-type Imaging of the Prostate: Implications for Planning and Guiding Biopsies and Focal Treatments<br/>Therapy Monitoring and Assessment Using Quantitative Ultrasound<br/>Review of Envelope Statistics Models for Quantitative Ultrasound Imaging and Tissue Characterization<br/>The Quantitative Ultrasound Diagnosis of Liver Fibrosis Using Statistical Analysis of the Echo Envelope<br/>Recent Applications of Acoustic Microscopy for Quantitative Measurement of Acoustic Properties of Soft Tissues<br/>Acoustic Microscopy of Cells<br/>Methods for Forward and Inverse Scattering in Ultrasound Tomography<br/>Clinical Results with Ultrasound Computed Tomography of the Breast.

::Summary## "The current text explores leadership within the context of a new understanding of complex adaptive systems and complex responsive processes. The leader is seen through a new lens of relational leadership in a way that emphasizes numerous skill sets for managing increasingly complex and diverse healthcare delivery systems in an era of constant movement and change. Rather than focus on the mechanics of operations and function, this text emphasizes the characteristics and role of the complexity leader through both describing the context of complexity and the application of the role as a leader of these complex systems. A revision of the text is needed to share the new science created supporting high levels of interdisciplinary team work as provide strategies for leaders to further advance their skills in leading complex, interdisciplinary teams. The most outstanding feature of this book is that it has an exceptionally unique focus that specifically addresses postindustrial, complex and highly mobile organizational systems and emphasizes the characteristics, elements, and role of leaders in guiding individuals and teams through effectively navigating work in these essentially new models. Quantum Leadership also integrates the essential requirements for Quality Matters certification of online courses that are used in many colleges and universities. Many more of the faculty and students using this textbook are in DNP programs and others are in leadership masters programs. These programs are contending with providing leadership within the context of a shifting healthcare landscape, the PPACA and increasing emphasis on trans disciplinary and value-based processes"--Publisher's description<br/>::Contents##<br/>A new landscape for leadership : changing the health script in an age of value<br/>Ten complexity principles for leaders advancing value in the quantum age<br/>Innovation leadership and professional governance : building the structure for transformation<br/>Innovation and opportunity : leading through the white water of change<br/>From evidence to innovation : measuring the foundations of practice and value<br/>Diversity and difference : managing conflict in a transdisciplinary network<br/>Leading constant movement : transforming chaos and crisis<br/>The focused leader : embracing vulnerability, risk taking, and the potential to succeed<br/>Transforming error and engaging failure toward a culture of safety<br/>The fully engaged leader : demonstrating capacity to sustain relationships<br/>Toxic organizations and people : the leader as transformer<br/>Coaching for unending change : transforming the membership community<br/>The leader's courage to be willing : building a context for hope<br/>Engaging the spirit of leadership : becoming a living leader.

::Contents##<br/>What is a quasispecies?- Historical origins and current scope<br/>The nucleation of semantic information in prebiotic matter<br/>Evolution of RNA-based networks<br/>Quasispecies on fitness landscapes<br/>Mathematical models of quasispecies theory and exact results for the dynamics<br/>Theoretical Models of Generalized Quasispecies<br/>Theories of lethal mutagenesis: from error catastrophe to lethal defection<br/>Estimating fitness of viral quasispecies from next-generation sequencing data<br/>Getting to know viral evolutionary strategies: Towards the next generation of quasispecies models<br/>Cooperative Interaction within RNA Virus Mutant Spectra<br/>Arenavirus Quasispecies And Their Biological Implications<br/>Models of viral population dynamics<br/>Fidelity variants and RNA quasispecies<br/>Antiviral strategies based on lethal mutagenesis and error threshold.

::Summary## As the first neurological hospital in the world, founded in 1859, the National Hospital, Queen Square, and its affiliated Institute of Neurology remain leading neurological centres providing exceptional clinical services, teaching and research. Illustrated by over 100 historical images and much unpublished archival material, this book provides a comprehensive history of the National Hospital, the Institute, and their staff. It relates the ups and downs of the Hospital and Institute in war and peacetime, their financial struggles, many personality conflicts, efforts to remain independent and to maintain neurological dominance, academic and clinical contributions, issues relating to specialisation and subspecialisation and relations between disciplines, and the changing roles of the Hospital and Institute. The history is told from varying perspectives against the backdrop of the evolution of British clinical neuroscience, the special position of London medicine, and the influence of world wars, and is set in the context of modern British social history.<br/>::Contents##<br/>Foundation and making of the National Hospital<br/>Queen Square, the salmon pink and other hospital buildings<br/>Queen square and neurology 1860-1902<br/>National Hospital quadrumvirate<br/>Roller-coaster ride and the National Hospital rubs along : 1902-1945<br/>Dominant National Hospital physicians<br/>NYS arrives and the hospital celebrates its centenary : 1946-1965<br/>Beyond the walls : British neurology outside Queen Square<br/>Neurosurgery and war neurology at Queen Square<br/>Other clinical specialties at Queen Square<br/>Neuropathology, neuroradiology and neurophysiology at Queen Square<br/>The Medical School and Institute of Neurology<br/>The rise of academic neurology at Queen Square : 1962-1997<br/>Change and integration : 1962-1997<br/>Medical and surgical appointees to the National Hospital and/or Institute of Neurology<br/>Senior administrative appointees at the National Hospital and/or Institute of Neurology<br/>Physicians<br/>National Hospital Queen Square 1860-1997.

::Summary## "In this book, personal accounts mingle with factual information and sensitive analysis to provide a snapshot of the joys and concerns of lesbian, gay, bisexual, transgender, queer, intersex, and asexual adolescents"-- Provided by publisher.<br/>::Contents##<br/>What is queer adolescence?<br/>Who we are<br/>Sex education<br/>Going through puberty<br/>Parental and peer involvement<br/>Exploring gender<br/>Exploring sexuality<br/>Coming out<br/>Transition<br/>What we wish had been different.

::Summary## This original fourteen chapter book is a brief, slightly autobiographic tale of medical oncologists, surgeons, radiation oncologists, and breast cancer patients in a well-established cancer center in Texas, who pursued the goal of cure for breast cancer. The evolution of improved outcomes in the treatment of microscopic metastatic breast cancer is also the story of the development of adjuvant chemotherapy for post-operative breast disease. The adjuvant therapy of breast cancer came about with the realization that this malignancy, when diagnosed in most patients, had spread beyond the confines of the primary cancer.<br/>::Contents##<br/>Anatomy of an Oncologist<br/>Milestones along the road to the cure<br/>The evolving goal of cure and inflammatory breast cancer<br/>Adjuvant therapy advances<br/>Marching forward<br/>Concluding thoughts.

::Summary## "Ace the echocardiography boards with this unique review tool! Questions, Tricks, and Tips for the Echocardiography Boards provides one-of-a-kind assistance directly from those who have recently passed the exam - including hundreds of questions and video clips that mimic what you're likely to encounter. The Second Edition also incorporates valuable feedback from Dr. Sorrell's recent fellows, ensuring complete, up-to-date coverage of the information you need to know to perform at your best on the exam"-- Provided by publisher.

::Summary## This book provides a practical and comprehensive review of pain medicine in a clear and easy to apply question-answer format. Divided by topic, the book includes Q&As on Pain Basics, Psychology, Common Pain Syndromes, Medications, Pain Management in Special Populations and Interventional Pain. It is intended as a guide for residents and fellows and is written in such a manner to provide instantaneous feedback on correct answer choice and explanation for self-evaluation while preparing for written board examinations. Questions and Answers in Pain Medicine: A Guide to Board Exams fulfills the need for a resource that is similar to the Accreditation Council for Graduate Medical Education (ACGME) board examination in the US as well as international equivalents. It utilizes a fully Q&A approach which is how many students prefer to study. Written by a physician who has recently passed the ACGME written board exam and the founder of a pain management fellowship program for nearly 20 years, the authors provide valuable insight for successfully undertaking board examinations in pain medicine. .<br/>::Contents##<br/>Pain Basics<br/>Psychology<br/>Common Pain Syndromes<br/>Medications<br/>Interventional Topics<br/>Other Topics.

::Summary## "This is the first book developed specifically for the Final FFICM structured oral examination. It is written by two senior trainees who have recently passed the exam and is edited by a consultant intensivist with a special interest in education. The book is designed in the style of the SOE, and provides model answers which include summaries of the relevant evidence to guide trainees in their preparation for the exam. The 91 topics and questions therein are drawn from previous exam sittings, and are expanded further to ensure each topic is covered in detail. This text is a valuable revision aid to those studying for the Final FFICM, and will also prove useful to trainees revising for the Final FRCA, as it covers popular ICM topics that often come up in the anaesthetic fellowship exams"--Provided by publisher.

::Summary## Enhance your knowledge of neonatal-perinatal medicine and/or study for Neonatal-Perinatal Medicine board certification with this new study guide from the editors of NeoReviews.

::Summary## "Quick Answers: Pharmacy provides concise, practical, expert information on the pharmacotherapy of common disorders. It is designed for quick and easy access to the drug therapy information you need for decision making in the clinical setting."--Preface<br/>::Contents##<br/>Acne Vulgaris--Acute Coronary Syndromes--Acute Kidney Injury--Adrenal Insufficiency--Alzheimer's Disease--Anemias--Antimicrobial Regimen Selection--Anxiety Disorder, Generalized--Anxiety Disorder, Social--Aspergillosis--Asthma--Atrial Fibrillation (AF)--Benign Prostatic Hyperplasia (BPH)--Bipolar Disorder--Bite Wounds--Blastomycosis--Bradyarrhythmias--Cancer, Breast--Bronchiolitis--Bronchitis, Acute--Bronchitis, Chronic--Candidiasis, Hematogenous--Cardiac Arrest--Cellulitis--Chlamydia--Chronic Kidney Disease-Drug Therapy Individualization--Chronic Kidney Disease (CKD)--Cirrhosis and Portal Hypertension--Coccidioidomycosis--Cancer, Colorectal--Constipation--Contraception--Chronic Obstructive Pulmonary Disease--Cryptococcosis--Cushing's Syndrome--Depressive Disorder, Major--Dermatitis, Atopic--Dermatitis, Contact--Dermatitis, Diaper--Dermatologic Drug Reactions--Diabetes Mellitus, Type 1--Diabetes Mellitus, Type 2--Diabetic Foot Infections--Diarrhea--Diarrhea, Infectious--Dyslipidemia--Endocarditis, Infective--Epilepsy--Erectile Dysfunction--Erysipelas--Gastroesophageal Reflux Disease--Glaucoma, Open-Angle--Gonorrhea--Gouty Arthritis--Headache, Migraine--Headache, Tension-Type--Chronic Heart Failure--Heart Failure, Acute Decompensated--Hepatitis A (HAV)--Hepatitis B (HBV)--Hepatitis C (HCV)--Herpes, Genital--Histoplasmosis--Human Immunodeficiency Virus (HIV) Infection--Hodgkin Lymphoma (HL)--Hypercalcemia--Hyperkalemia--Hypermagnesemia--Hypernatremia--Hyperphosphatemia--Hypertension--Hyperthyroidism--Hyperuricemia--Hypocalcemia--Hypokalemia--Hypomagnesemia--Hyponatremia--Hypophosphatemia--Hypothyroidism--Impetigo--Inflammatory Bowel Disease (IBD): Crohn's Disease (CD)--Influenza--Insomnia--Lung Cancer--Meningitis, Bacterial--Menopause and Postmenopausal Therapy--Metabolic Acidosis--Metabolic Alkalosis--Narcolepsy--Nausea and Vomiting--Non-Hodgkin Lymphoma--Nutrition Assessment--Nutrition, Enteral--Nutrition, Parenteral--Obesity--Osteoarthritis--Osteoporosis--Otitis Media, Acute--Pain Management--Pancreatitis, Acute--Pancreatitis, Chronic--Panic Disorder--Parkinson Disease--Peptic Ulcer Disease--Peritonitis, Bacterial--Pharyngitis--Pneumonia, Community-Acquired--Postpartum Therapeutic Considerations--Posttraumatic Stress Disorder--Pregnancy: Therapeutic Considerations--Pressure Sores--Prostate Cancer--Psoriasis--Renal Cell Carcinoma--Respiratory Acidosis--Respiratory Alkalosis--Rheumatoid Arthritis (RA)--Rhinitis, Allergic--Schizophrenia--Sepsis and Septic Shock--Shock--Sickle Cell Disease (SCD)--Sinusitis--Sleep Apnea--Stable Ischemic Heart Disease--Status Epilepticus--Stroke, Ischemic--Substance-Related Disorders: Alcohol--Substance-Related Disorders: Benzodiazepines--Substance-Related Disorders: Cocaine--Substance-Related Disorders: Nicotine--Substance-Related Disorders: Opioids--Surgical Prophylaxis--Syphilis--Tachycardia, Paroxysmal Supraventricular--Tachycardia, Ventricular--Trichomoniasis--Tuberculosis--Inflammatory Bowel Disease (IBD): Ulcerative Colitis (UC)--Urinary Incontinence--Urinary Tract Infections--Vaccines, Toxoids, and Other Immunobiologics--Venous Thromboembolism.

::Summary## "Quick Answers: Pharmacy provides concise, practical, expert information on the pharmacotherapy of common disorders. It is designed for quick and easy access to the drug therapy information you need for decision making in the clinical setting."--Preface<br/>::Contents##<br/>Acne Vulgaris--Acute Coronary Syndromes--Acute Kidney Injury--Adrenal Insufficiency--Alzheimer's Disease--Anemias--Antimicrobial Regimen Selection--Anxiety Disorder, Generalized--Anxiety Disorder, Social--Aspergillosis--Asthma--Atrial Fibrillation (AF)--Benign Prostatic Hyperplasia (BPH)--Bipolar Disorder--Bite Wounds--Blastomycosis--Bradyarrhythmias--Cancer, Breast--Bronchiolitis--Bronchitis, Acute--Bronchitis, Chronic--Candidiasis, Hematogenous--Cardiac Arrest--Cellulitis--Chlamydia--Chronic Kidney Disease-Drug Therapy Individualization--Chronic Kidney Disease (CKD)--Cirrhosis and Portal Hypertension--Coccidioidomycosis--Cancer, Colorectal--Constipation--Contraception--Chronic Obstructive Pulmonary Disease--Cryptococcosis--Cushing's Syndrome--Depressive Disorder, Major--Dermatitis, Atopic--Dermatitis, Contact--Dermatitis, Diaper--Dermatologic Drug Reactions--Diabetes Mellitus, Type 1--Diabetes Mellitus, Type 2--Diabetic Foot Infections--Diarrhea--Diarrhea, Infectious--Dyslipidemia--Endocarditis, Infective--Epilepsy--Erectile Dysfunction--Erysipelas--Gastroesophageal Reflux Disease--Glaucoma, Open-Angle--Gonorrhea--Gouty Arthritis--Headache, Migraine--Headache, Tension-Type--Chronic Heart Failure--Heart Failure, Acute Decompensated--Hepatitis A (HAV)--Hepatitis B (HBV)--Hepatitis C (HCV)--Herpes, Genital--Histoplasmosis--Human Immunodeficiency Virus (HIV) Infection--Hodgkin Lymphoma (HL)--Hypercalcemia--Hyperkalemia--Hypermagnesemia--Hypernatremia--Hyperphosphatemia--Hypertension--Hyperthyroidism--Hyperuricemia--Hypocalcemia--Hypokalemia--Hypomagnesemia--Hyponatremia--Hypophosphatemia--Hypothyroidism--Impetigo--Inflammatory Bowel Disease (IBD): Crohn's Disease (CD)--Influenza--Insomnia--Lung Cancer--Meningitis, Bacterial--Menopause and Postmenopausal Therapy--Metabolic Acidosis--Metabolic Alkalosis--Narcolepsy--Nausea and Vomiting--Non-Hodgkin Lymphoma--Nutrition Assessment--Nutrition, Enteral--Nutrition, Parenteral--Obesity--Osteoarthritis--Osteoporosis--Otitis Media, Acute--Pain Management--Pancreatitis, Acute--Pancreatitis, Chronic--Panic Disorder--Parkinson Disease--Peptic Ulcer Disease--Peritonitis, Bacterial--Pharyngitis--Pneumonia, Community-Acquired--Postpartum Therapeutic Considerations--Posttraumatic Stress Disorder--Pregnancy: Therapeutic Considerations--Pressure Sores--Prostate Cancer--Psoriasis--Renal Cell Carcinoma--Respiratory Acidosis--Respiratory Alkalosis--Rheumatoid Arthritis (RA)--Rhinitis, Allergic--Schizophrenia--Sepsis and Septic Shock--Shock--Sickle Cell Disease (SCD)--Sinusitis--Sleep Apnea--Stable Ischemic Heart Disease--Status Epilepticus--Stroke, Ischemic--Substance-Related Disorders: Alcohol--Substance-Related Disorders: Benzodiazepines--Substance-Related Disorders: Cocaine--Substance-Related Disorders: Nicotine--Substance-Related Disorders: Opioids--Surgical Prophylaxis--Syphilis--Tachycardia, Paroxysmal Supraventricular--Tachycardia, Ventricular--Trichomoniasis--Tuberculosis--Inflammatory Bowel Disease (IBD): Ulcerative Colitis (UC)--Urinary Incontinence--Urinary Tract Infections--Vaccines, Toxoids, and Other Immunobiologics--Venous Thromboembolism.

::Contents##<br/>Abscess, Brain<br/>Acoustic Neuroma<br/>Acquired Coagulation Disorders<br/>Addison Disease<br/>Adhesive Capsulitis<br/>Adrenal Gland Hyperfunction<br/>Alzheimer'S Disease<br/>Amputation Transfemoral (AK)<br/>Amputation Transtibial (BK)<br/>Appendicitis<br/>Arthritis, Juvenile Rheumatoid<br/>Arthritis, Rheumatoid<br/>Arthrogryposis<br/>Asthma<br/>Autism Spectrum Disorder<br/>Avascular Necrosis, Femoral Head.

::Contents##<br/>Abscess, Brain<br/>Acoustic Neuroma<br/>Acquired Coagulation Disorders<br/>Addison Disease<br/>Adhesive Capsulitis<br/>Adrenal Gland Hyperfunction<br/>Alzheimer'S Disease<br/>Amputation Transfemoral (AK)<br/>Amputation Transtibial (BK)<br/>Appendicitis<br/>Arthritis, Juvenile Rheumatoid<br/>Arthritis, Rheumatoid<br/>Arthrogryposis<br/>Asthma<br/>Autism Spectrum Disorder<br/>Avascular Necrosis, Femoral Head.

::Summary## Medicine is an ever-changing science. As new research and clinical experience broaden our knowledge, changes in treatment and drug therapy are required. The authors and the publisher of this work have checked with sources believed to be reliable in their efforts to provide information that is complete and generally in accord with the standards accepted at the time of publication. However, in view of the possibility of human error or changes in medical sciences, neither the authors nor the publisher nor any other party who has been involved in the preparation or publication of this work warrants that the information contained herein is in every respect accurate or complete, and they disclaim all responsibility for any errors or omissions or for the results obtained from use of the information contained in this work. Readers are encouraged to confirm the information contained herein with other sources. For example and in particular, readers are advised to check the product information sheet included in the package of each drug they plan to administer to be certain that the information contained in this work is accurate and that changes have not been made in the recommended dose or in the contraindications for administration. This recommendation is of particular importance in connection with new or infrequently used drugs.<br/>::Contents##<br/>Abdominal Aortic Aneurysm<br/>Acromegaly and the Heart<br/>Adrenal Insufficiency and the Heart<br/>AIDS and the Heart<br/>Angina Pectoris, Unstable<br/>Ankylosing Spondylitis and the Heart<br/>Aortic Regurgitation, Acute<br/>Aortic Regurgitation, Chronic<br/>Aortic Stenosis<br/>Aortic Stenosis, Subvalvular<br/>Aortic Stenosis, Supravalvular<br/>Athlete's Heart<br/>Atrial Fibrillation<br/>Atrial Flutter<br/>Atrial Septal Defect (ASD)<br/>Atrial Tachycardia, Automatic (Ectopic)<br/>Atriofascicular Tachycardia (Mahaim Tachycardia)<br/>Atrioventricular Canal Defects<br/>Atrioventricular Nodal-His Block<br/>Atrioventricular Nodal Reentrant Tachycardia<br/>Atrioventricular Reciprocating Tachycardia: Preexcitation<br/>Bicuspid Aortic Valve<br/>Brugada Syndrome<br/>Buerger's Disease (Thromboangiitis Obliterans)<br/>Bundle Branch Reentrant Ventricular Tachycardia<br/>Carcinoid and the Heart<br/>Cardiac Allograft Vasculopathy<br/>Cardiac Cachexia<br/>Cardiac Contusion/Blunt Trauma<br/>Cardiac Syndrome X (Microvascular Angina Pectoris)<br/>Cardiac Tamponade<br/>Cardiogenic Shock<br/>Cardiomyopathy, Alcoholic<br/>Cardiomyopathy, Hypertrophic<br/>Cardiomyopathy, Idiopathic Dilated<br/>Cardiomyopathy, Peripartum<br/>Cardiomyopathy, Restrictive<br/>Cardiomyopathy, Tachycardia Induced<br/>Cardiomyopathy, Takotsubo, or Stress Induced<br/>Carotid Sinus Hypersensitivity (CSH)<br/>Cerebral Vascular Disease<br/>Chagas' Heart Disease<br/>Chemotherapy-Induced Cardiac Disease<br/>Coarctation of the Aorta<br/>Cocaine-Induced Cardiovascular Disease<br/>Congestive Heart Failure: Preserved Ejection Fraction<br/>Congestive Heart Failure: Reduced Ejection Fraction<br/>Contrast Nephropathy<br/>Cor Pulmonale/Right Heart Failure<br/>Coronary Artery Disease, Symptomatic Non-Revascularizable<br/>Cushing's Syndrome<br/>Deep Venous Thrombosis<br/>Diabetic Cardiomyopathy<br/>Digoxin Toxicity<br/>Ebstein's Anomaly<br/>Effort Syncope<br/>Eisenmenger's Syndrome<br/>Endocarditis, Infective<br/>Fontan Operation<br/>Friedreich's Ataxia, Cardiac Manifestations<br/>Heart Disease in Pregnancy<br/>Hemochromatosis and the Heart<br/>Hibernating and Stunned Myocardium<br/>High-Altitude Pulmonary Edema<br/>High-Output Heart Failure<br/>HIV and the Heart<br/>Hyperaldosteronism, Primary<br/>Hyperlipidemia (Lipid Disorders)<br/>Hyperparathyroidism and the Heart<br/>Hypertension, Gestational<br/>Hypertension, Renovascular<br/>Hypertension, Resistant or Refractory<br/>Hypertension, Systemic<br/>Hypertensive Emergencies<br/>Hypertensive Nephrosclerosis<br/>Hyperthyroid Heart Disease<br/>Hypotension Complicating Hemodialysis<br/>Hypothyroid Heart Disease<br/>Implantable Cardioverter-Defibrillator, Frequent Discharges<br/>Inherited Neuromuscular Disease and the Heart<br/>In-Stent Restenosis<br/>Intra-atrial Reentrant/Macroreentrant Tachycardia<br/>Ischemic Heart Disease, Chronic<br/>Kawasaki Disease<br/>Left Atrial Myxoma<br/>Left Ventricular Aneurysm<br/>Left Ventricular Free Wall Rupture, Acute<br/>Localized Lymphedema<br/>Long QT Syndrome<br/>Lyme Carditis<br/>Lutembacher's Syndrome<br/>Marfan's Syndrome<br/>Metabolic Abnormalities and Cardiovascular Disease<br/>Metabolic Syndrome and the Heart<br/>Mitral Regurgitation, Acute<br/>Mitral Regurgitation, Chronic Functional<br/>Mitral Regurgitation, Chronic Organic<br/>Mitral Stenosis<br/>Mixed Aortic Valve Disease<br/>Mixed Connective Tissue Disease and the Heart<br/>Mixed Mitral Valve Disease<br/>Multifocal Atrial Tachycardia<br/>Myocardial Infarction, Acute Non-ST-Segment Elevation<br/>Myocardial Infarction, Acute ST-Segment Elevation<br/>Myocardial Infarction with Normal Coronary Arteries, Acute<br/>Myocardial Infarction, Right Ventricular<br/>Myocardial Ischemia, Asymptomatic<br/>Myocarditis<br/>Neurocardiogenic Syncope<br/>Nonparoxysmal Junctional Tachycardia<br/>Obesity and Heart Disease<br/>Orthostatic Hypotension<br/>Pacemaker Malfunction<br/>Pacemaker Syndrome<br/>Paroxysmal Atrial Tachycardia With Block<br/>Partial Anomalous Pulmonary Venous Connection<br/>Patent Ductus Arteriosus<br/>Patent Foramen Ovale/Atrial Septal Aneurysm<br/>Pericardial Effusion<br/>Pericarditis, Acute<br/>Pericarditis, Constrictive<br/>Pericarditis, Effusive-Constrictive<br/>Peripheral Arterial Atherosclerosis Obliterans<br/>Periprosthetic Valve Leaks<br/>Permanent Junctional Reciprocating Tachycardia<br/>Pheochromocytoma<br/>Polymyositis/Dermatomyositis and the Heart<br/>Postural Tachycardia Syndrome<br/>Pulmonary Arterial Hypertension<br/>Pulmonary Atresia With Intact Ventricular Septum<br/>Pulmonary Atresia With Ventricular Septal Defect<br/>Pulmonary Edema, Acute<br/>Pulmonary Edema, Noncardiogenic<br/>Pulmonary Embolism<br/>Pulmonic Regurgitation<br/>Pulmonic Stenosis<br/>Radiation Heart Disease<br/>Raynaud's Phenomenon<br/>Renal Dysfunction in Heart Failure<br/>Rheumatic Fever, Acute<br/>Rheumatoid Arthritis and the Heart<br/>Scleroderma and the Heart<br/>Sexual Dysfunction in Cardiac Disease<br/>Sinus Arrhythmia<br/>Sinus Bradycardia<br/>Sinus Node Dysfunction<br/>Sinus Node Reentry<br/>Sinus of Valsalva Aneurysm<br/>Sinus Tachycardia<br/>Sinus Tachycardia, Inappropriate<br/>Subclavian Coronary Artery Steal Syndrome<br/>Sudden Cardiac Death (SCD)<br/>Sudden Death in Athletes<br/>Superficial Thrombophlebitis<br/>Superior Vena Cava Syndrome<br/>Syncope<br/>Systemic Lupus Erythematosus and the Heart<br/>Takayasu's Arteritis<br/>Tetralogy of Fallot<br/>Thoracic Aortic Aneurysm<br/>Thoracic Aortic Dissection<br/>Torsades de Pointes<br/>Total Anomalous Pulmonary Venous Drainage<br/>Transposition (Complete) of the Great Arteries<br/>Transposition of the Great Arteries, Congenitally Corrected<br/>Tricuspid Atresia<br/>Tricuspid Regurgitation<br/>Tricuspid Stenosis<br/>Tricyclic Antidepressants, Cardiac Effects<br/>Truncus Arteriosus<br/>Tumors of the Heart, Metastatic<br/>Tumors of the Heart, Primary (Excluding Myxoma)<br/>Variant or Prinzmetal's Angina<br/>Venous Insufficiency<br/>Ventricular Arrhythmia, Idiopathic<br/>Ventricular Septal Defect<br/>Ventricular Septal Rupture, Acute<br/>Ventricular Tachycardia<br/>Wandering Atrial Pacemaker.

::Contents##<br/>Intro<br/>Preface<br/>Contents<br/>About the Authors<br/>Chapter 1: Anaphylaxis: Definition, History, and Epidemiology<br/>1.1 Definition of Anaphylaxis<br/>1.2 History<br/>1.3 Epidemiology of Anaphylaxis<br/>References<br/>Chapter 2: The Aetiology of Anaphylaxis<br/>2.1 Food Allergy<br/>2.1.1 Background<br/>2.1.2 Definition of Food Allergy<br/>2.1.3 Epidemiology<br/>2.1.3.1 Sex- and Age-Related Demographics<br/>2.1.4 Aetiology<br/>2.1.4.1 IgE Antibody-Mediated Responses<br/>2.1.4.2 Cell-Mediated Responses<br/>2.1.5 Symptoms of Food Allergy<br/>2.1.6 Food Allergy Triggers<br/>2.1.7 Diagnosing Food Allergies 2.1.8 Characteristics of Food Allergens<br/>2.1.9 Risk Factors<br/>2.1.10 Management and Treatment<br/>2.1.10.1 Investigational Therapeutic Interventions for Food Allergy<br/>2.1.10.2 Patient Education<br/>Preparation<br/>Avoidance of Allergens<br/>2.1.11 Anaphylaxis<br/>2.1.12 Food Allergy Action Plan<br/>2.1.13 Prognosis<br/>2.2 Drug Allergy<br/>2.2.1 Definition of Drug Allergy<br/>2.2.2 Classification of Drug Allergy<br/>2.2.3 Epidemiology<br/>2.2.4 Drug Allergy and Anaphylaxis<br/>2.2.5 Risk Factors for Drug Allergy<br/>2.2.5.1 Drug-Related Factors<br/>2.2.5.2 Factors Related to the Host 2.2.6 Genetics of Drug Allergy<br/>2.2.7 History and Physical Examination<br/>2.2.8 Diagnostic Tests<br/>2.2.9 Specific Drugs and Biologic Agents and Drug Allergy<br/>2.2.9.1 Antimicrobials<br/>2.2.9.2 Insulin and Oral Antidiabetic Drugs<br/>2.2.9.3 Cancer Chemotherapeutic Agents<br/>2.2.9.4 Medications for Patients with HIV Infections and AIDS<br/>2.2.9.5 Medications for Autoimmune Diseases<br/>2.2.9.6 Perioperative Agents and Blood Products<br/>2.2.9.7 Opiates<br/>2.2.9.8 Corticosteroids<br/>2.2.9.9 Heparin<br/>2.2.9.10 Local Anaesthetics<br/>2.2.9.11 Radio-Contrast Media<br/>2.2.9.12 Biologic Modifiers 2.3 Venom Allergy<br/>2.3.1 Background<br/>2.3.2 Pathophysiology<br/>2.3.3 Epidemiology<br/>2.3.4 Symptoms<br/>2.3.4.1 Local Reactions<br/>2.3.4.2 Generalised Reactions<br/>2.3.5 Diagnosis<br/>2.3.6 Prognosis<br/>2.3.7 Treatment<br/>2.3.7.1 Emergency Department Care<br/>Epinephrine (Adrenalin, Bronitin, EpiPen)<br/>Bronchodilators<br/>Salbutamol (Ventolin)<br/>Antihistamines<br/>Systemic Corticosteroids<br/>Anti-tetanus Immunoglobulin<br/>2.3.7.2 Desensitisation (Immunotherapy)<br/>Mechanism of immunotherapy<br/>2.4 Allergic Rhinitis, Asthma, and Anaphylaxis<br/>2.4.1 Background<br/>2.4.2 Asthma and Anaphylaxis 2.4.2.1 Pathophysiology<br/>Inflammation Occurring Within Airways<br/>Discontinuous Blockage of Air Entry and Exit<br/>Overreactive Bronchi<br/>2.4.2.2 Aetiology<br/>2.4.2.3 Manifestations of an Acute Episode<br/>Mild Episodes<br/>Moderate Severity<br/>High Severity<br/>Pre-respiratory Arrest<br/>2.4.2.4 Symptoms of an Asthma Emergency<br/>2.4.2.5 Incidence of Anaphylactic Shock in Asthma<br/>2.4.3 Allergic Rhinitis and Anaphylaxis<br/>2.4.3.1 Pathophysiology<br/>2.4.3.2 Symptoms and Chronicity<br/>2.4.3.3 Trigger Factors<br/>2.4.3.4 Comorbid Conditions<br/>2.4.3.5 Mortality/Morbidity

::Contents##<br/>Immunology: A Quick Guide<br/>Clinical Features of Contact Dermatitis<br/>Patch Testing: Essentials<br/>Patch Testing with Own Products<br/>Allergic Contact Dermatitis: Clinical Relevance and Exposure Assessment of Allergens<br/>Irritant Contact Dermatitis: Diagnosis and Risk Factors<br/>Photoreactions and Testing<br/>Protein Contact Dermatitis and Testing<br/>Occupational Contact Dermatitis<br/>Contact Allergy in Children<br/>Main Allergen Groups: Metals<br/>Fragrances<br/>Preservatives. Allergens in Various Products: Textiles and Hair Dyes<br/>Dental Materials<br/>Shoes/Gloves<br/>Glues<br/>Metalworking Fluids<br/>Plants<br/>Cosmetics<br/>Workers Protection: Gloves, Creams<br/>Overview of Allergens.

::Summary## This quick guide demonstrates the value of dermoscopy before, during, and after the treatment of a wide variety of vascular and other skin lesions with laser and/or intense pulsed light (IPL). The coverage includes the treatment of benign pigmented pathologies, melanocytic nevi, seborrheic dermatoses, solar lentigines, telangiectasias, flat angiomas, port-wine scars, other vascular pathologies, keloids and hypertrophic scars, acne and post-traumatic scars, and tattoos. Practically oriented information is also supplied on the dermoscopic technique, the principles of use of lasers and IPL in dermatology, laser-tissue interactions, and types of laser. This will help the reader to comprehend the importance of lasers and IPL in clinical practice and provide excellent preparation for the use of dermoscopy to visualize the targets to be hit with laser or IPL. The inclusion of more than 100 color photos stored before, during, and after dermoscopy-aided laser or IPL treatment documents the results that can be achieved even in pathologies that were very difficult to cure until several years ago.<br/>::Contents##<br/>Preface<br/>1 The dermoscopic technique and equipment<br/>2 Laser in dermatology: basic principles<br/>3 Laser-tissue interaction<br/>4 Types of lasers<br/>5 Intense pulsed light: basic principles and phototherapy<br/>6 Dermoscopy applied to laser and IPL treatments: benign pigmented pathologies.<br/>7 Dermoscopy applied to laser and IPL treatments: melanocytic nevi<br/>8 Dermoscopy applied to laser and IPL treatments: seborrheic dermatoses and solar lentigo<br/>9 Dermoscopy and vascular pathologies<br/>10 Dermoscopy and telangiectasias<br/>11 Dermoscopy in the treatment of flat angiomas and port-wine scars<br/>12 Dermoscopy for treating keloids and hypertrophic scars<br/>13 Dermoscopy in the treatment of acne and post-traumatic scars<br/>14 Dermoscopy in the removal of tattoos<br/>15 Conclusions.

::Summary## This brand-new book offers a reference guide to understanding and applying the rules for properly conducting clinical trials to meet the international quality standard - Good Clinical Practice - provided by the International Conference on Harmonization (ICH). The work offers an updated perspective on the clinical research landscape within the context of the clinical trial regulatory frameworks in Europe and the USA. In addition to providing a historical review and a detailed definition of GPC regulations, it includes step-by-step explanations of all the requirements that researchers should bear in mind when designing and performing new trials. Further topics covered include: ethics of clinical research; the drug development process and evolution of regulations; investigator and sponsor responsibilities; and clinical trial protocols. Written by clinicians for clinicians, the book represents a valuable read also for researchers, pharmacists and all professionals involved in applications to the ethic committees, whose approval is required for new clinical studies.<br/>::Contents##<br/>1 Clinical Trials: Historical Aspects and Importance and New Drug Developments<br/>2 The Definition of GCP<br/>3 The Principles of GCP<br/>4 The Drug Development Process and Evolution of Regulations<br/>5 Planning Clinical Research<br/>6 Preparation of Ethics Committee (IRB) Proposal<br/>7 Preparation of Informed Consent<br/>8 Preparation of Findings Tables<br/>9 Setting the Ideal Statistical Methods<br/>10 The Duties of a Clinical Research Coordinator<br/>11 The Duties of Clinical Researchers<br/>12 The Phases of Clinical Studies<br/>13 Safety in Clinical Trials<br/>14 Setting the Size<br/>15 Setting the Ideal Method<br/>16 Ethics of Clinical Research<br/>17 Recruitment and Enrolment<br/>18 Why we need Clinical Consent and Other Documentation<br/>19 Monitoring the Trial<br/>20 Inspection<br/>21 Ethics<br/>Institutional Review Board/Independent Ethics Committee(IRB/IEC)<br/>22 Responsibilities of the Investigator<br/>23 Responsibilities of the Sponsor<br/>24.Clinical Trial Protocols.

::Summary## This book is intended to provide a quick guide to the field of pediatric retina. It has been long accepted that retinal disorders in children differ from those in adults. Although there are plenty of published books on retinal diseases, most of them only cover adult retinal disorders. Therefore, information on pediatric retinal diseases is urgently needed. The book combines comprehensive information with rich illustrations to offer readers an in-depth understanding of the two main themes: retinopathy of prematurity (ROP) and other pediatric vitreoretinal disorders. World-renowned pediatric retina experts share their insights and research findings in areas such as ROP, familiar exudative vitreoretinopathy, Coats disease, retinoblastoma, congenital x-linked retinoschisis and hereditary retinal diseases. Topics concerning modern and future medicine such as tele-screening for ROP, E-learning for ROP, and deep learning for ROP are also included. Designed to help readers understand the contents as quickly as possible, the book includes many useful tips and pearls, as well as easy-to-follow figures. It covers the majority of pediatric retinal diseases and offers essential information on their diagnosis and management. In addition, relevant and up-to-date references are provided for those who want to explore the topics in more depth. As such, the book offers an excellent reference guide to caring for these young patients.<br/>::Contents##<br/>Part 1 ROP<br/>1 The Pathophysiology of Retinopathy of Prematurity<br/>2 Animal Models of Retinopathy of Prematurity<br/>3 Evolution of Major Clinical Trials in ROP<br/>4 Diagnosis and classification of ROP<br/>5 Differential diagnosis of ROP<br/>6 Aggressive Posterior Retinopathy of Prematurity (APROP)<br/>7 Familial Exudative Vitreo-Retinopathy or Retinopathy of Prematurity<br/>8 Telemedicine in Retinopathy of Prematurity<br/>9 Optical Coherence Tomography in Retinopathy of Prematurity<br/>10 FA in ROP<br/>11 Laser Treatment for Retinopathy of Prematurity<br/>12 Anti-VEGF in ROP<br/>13 Surgical Management of Stage 4 ROP<br/>14 Surgical Management of Stage 5 Retinopathy of Prematurity<br/>15 Endoscopic surgery in ROP<br/>16 Foveal Development in Retinopathy of Prematurity<br/>17 Neurodevelopmental outcome following anti-VEGF treatment for ROP<br/>18 Artificial Intelligence for Retinopathy of Prematurity Diagnosis<br/>19 E-Education in ROP<br/>20 Ultra wide-field imaging in pediatric retinal diseases<br/>Part 2 Non-ROP Pediatric Retina<br/>21 Retinoblastoma<br/>22 Paediatric Intra-Ocular Tumours (Non-RB)<br/>23 Congenital X-Linked Retinoschisis<br/>24 Inherited retinal degenerations in the pediatric population<br/>25 Familial Exudative Vitreoretinopathy<br/>26 Persistent Fetal Vasculature<br/>27 Pediatric Uveitis<br/>28 Coats' disease<br/>29 Stickler Syndrome and associated Collagenopathies<br/>30 Genetic testing in pediatric retina<br/>31 Pediatric Macular Hole<br/>32 Non-accidental trauma<br/>33 Rhegmatogenous Retinal Detachments in the Pediatric Population and Special Considerations for Pediatric Vitreo-retinal Surgery.

::Contents##<br/>Medical and psychiatric history<br/>Physical exam<br/>Laboratory testing and studies<br/>Suicide risk assessment<br/>Agitation<br/>Anxiety<br/>Catatonia<br/>Depression<br/>Mania<br/>Psychosis<br/>Adrenal crisis/adrenal insufficiency<br/>Chronic pain<br/>Delirium<br/>Dementia<br/>Encephalitis<br/>Head injury<br/>Hepatic encephalopathy<br/>Hypercalcemia<br/>Hypercortisolism (Cushing's syndrome)<br/>Hypoglycemia<br/>Hyponatremia<br/>Hypothyroidism<br/>Myxedema coma<br/>Non-epileptic seizures<br/>Seizures<br/>Thyrotoxicosis<br/>Wernicke-Korsakoff Syndrome<br/>Acute intoxication : general principles<br/>Phenethylamines intoxication (amphetamines, methamphetamine, cathinones, and "designer amphetamines")<br/>Cocaine intoxication<br/>Ethanol (alcohol) intoxication<br/>GHB, GBL intoxication<br/>Inhalant (alkyl nitrates, nitrous oxide, hydrocarbons) intoxication AKA : poppers<br/>MDMA (Ecstasy, Molly) intoxication<br/>Opiates, opioids intoxication<br/>Psychedelic drug (LSD, PCP, hallucinogenic mushrooms) intoxication<br/>Acute withdrawal : general principles<br/>Alcohol withdrawal<br/>Amphetamine withdrawal<br/>Barbiturate withdrawal<br/>Benzodiazepine withdrawal<br/>Cannabis withdrawal<br/>Cocaine withdrawal<br/>Opiate/opioid withdrawal<br/>Antidepressant discontinuation syndrome<br/>Anti-muscarinic toxicity<br/>Common medications which may mimic psychiatric symptoms<br/>Lithium toxicity<br/>Neuroleptic malignant syndrome<br/>Salicylate toxicity<br/>Serotonin syndrome<br/>Neuropsychiatric complications of steroids<br/>Valproic acid toxicity.

::Summary## This book covers essential information necessary in diagnosing and treating pediatric patients in the emergency room. Emergencies require quick and precise decision making that does not allow for extended reading or fact-checking to ensure all factors are considered. This pocket guide addresses that need by placing vital clinical management and algorithms into a quick and simple guidebook that can be accessed within moments from a scrub pocket or white coat. It is an easy, quick access reference that can be used for those facts that are absolutely essential, but are often difficult to remember. Color images and flow charts allow doctors to grasp the essentials quickly, while more detailed explanations are included alongside for trainees. Quick Hits for Pediatric Emergency Medicine uses tips, caveats, drug dosing, and pearls to assist the provider who may not be familiar with all of the unique nuances of the pediatric population. This is ideal for emergency department physicians, nurses, and trainees including students, residents, and fellows.<br/>::Contents##<br/>Intro; Foreword; Contents; Contributors; <br/>Chapter 1: Airway: Pediatric Anatomy, Infants and Children; Before You Intubate: What You Need to Know; Lung Physiology; Lung Mechanics; Tips for Intubation; Ventilation Equipment; <br/>Chapter 2: Respiratory Review: A, B, C, and P of Kids (Asthma, Bronchiolitis, Croup, and Pneumonia); Respiratory Overview; Asthma; Clinical Presentation; Treatment; Considerations for Severe Asthma; Asthma Pearls; Pediatric Asthma Score; Bronchiolitis; Clinical Presentation; Treatment; Supportive; Bronchiolitis Score; Croup (Laryngotracheobronchitis); Clinical Presentation Clinical Presentation with the FollowingTreatment; Westley Score; Pneumonia; Clinical Presentation; Treatment; Pediatric Pneumonia; <br/>Chapter 3: Resuscitation: Pediatric Algorithms; Resuscitation: Pediatric Algorithms (Figs. 3.1, 3.2, 3.3, and 3.4); <br/>Chapter 4: Pediatric Pearls: Management of Shock in Children; Shock; Cardiac Output (CO) = Heart Rate (HR) × Stoke Volume (SV); Quick Hit Cardiac Pearls; Definition of Hypotension by Systolic Blood Pressure and Age; Heart Rate and Perfusion Pressure for Age; Pediatric CPR; Pediatric Pearls; SIRS Criteria Common Pediatric Medications for Resuscitation and Cardiac Arrest<br/>Chapter 5: Pediatric Ventilator Management; Noninvasive Modes of Ventilation; Invasive Ventilation; Types of Ventilator Support; Modes of Ventilation; Initial Ventilator Settings; DOPES; <br/>Chapter 6: Neonatal Delivery and the Acutely Ill Neonate; Neonates (Age ≤ 28 Days); Causes of Severe Illness in Neonates: THE MISFITS; Newborn Delivery and Resuscitation (Fig. 6.1); MR SOPA Ventilation Correction Steps; Newborn Resuscitation Medications; Endotracheal Intubation Guide; UVC Placement; Supplies Needed; Procedure (Figs. 6.2 and 6.3) APGAR Score<br/>Chapter 7: Pediatric Abdominal Pain; Common Diagnoses with Work-Up and Management; Differential Diagnosis for Abdominal Pain Stratified by Age; Quick Hits Abdominal Pain Pearls; <br/>Chapter 8: Trauma Tidbits; Glasgow Coma Scale; Fluid Resuscitation Guidelines; Fluid Maintenance Requirements; Fluid Replacement for Burns; Adequate Urine Output; Blood Replacement Guidelines; Tube Sizes (French); General Considerations for Pediatric Trauma Patients; Size and Shape; Skeleton; Surface Area; ABCDE of Pediatric Trauma Management; Airway and Cervical Spine Stabilization Breathing and VentilationCirculation and Hemorrhage Control; Disability; Exposure; Quick Hits Pediatric Trauma Pearls; <br/>Chapter 9: Pediatric Head Injury Guidelines; Pediatric Head Injury Guidelines; Pediatric Blunt Head Injury, Less Than 2 Years Old (Fig. 9.1); Pediatric Blunt Head Injury, 2 Years Old and Older (Fig. 9.2); <br/>Chapter 10: Pediatric Burns; Etiology; Work-Up; Classification of Burns; Management; Disposition; Estimating Body Surface Area for Burns (Fig. 10.1); Quick Hits: Pediatric Burn Pearls; <br/>Chapter 11: Procedure Pearls; Airway Adjuncts

::Summary## For important information you need to know, but can't remember, turn to QUICK HITS IN EMERGENCY MEDICINE. This practical, short compendium contains the key decision-rules, clinical values, mnemonics, and dosages that you need at your finger tips in the ED. It covers everything from acute coronary syndrome and ACLS, to electrolyte equations and hyperkalemia, to ventilator settings by disease to Wellen's syndrome. Information on each topic is limited to a single page and presented in easily digested formats such as tables, algorithms, bulleted lists, and clinical illustrations.<br/>::Contents##<br/>ACLS<br/>Intubation, airway, and mechanical ventilation<br/>Sepsis and resuscitation<br/>Pulmonary decision rules and COPD<br/>Fluid and electrolytes<br/>Neurology<br/>Trauma and ATLS<br/>Head CT decision rules and intracranial hemorrhage<br/>Cervical spine injury and decision rules<br/>CXR interpretation<br/>Orthopedics and decision rules<br/>Cardiology<br/>GI bleeding/hemorrhage<br/>Hematology<br/>Toxicology<br/>Ultrasound and pregnancy<br/>The red eye<br/>Pediatrics<br/>Head and neck<br/>Statistics<br/>Infustions, pressors, and RSI.

::Summary## This book provides easy to follow guidance on how to manage emergency situations and common problems in obstetric anesthesia. The book provides different anesthetic recipes for obstetric procedures and describes challenges that will be encountered on a day-to-day basis. There are trouble-shooting chapters and what to do lists for frequent dilemmas. The book covers obstetric-specific resuscitation and medical emergencies seen on the labor ward. Antenatal and postpartum complications relating to anesthesia are covered as well as issues that may arise during follow up of patients who have had neuraxial anesthesia during delivery. Quick Hits in Obstetric Anesthesia should be used as a cognitive aid for emergency cases and as a decision-making tool for urgent management plans. It is a guide to common problems and provides core knowledge to facilitate anesthesia care on labor wards for all grades of anesthetist.<br/>::Contents##<br/>Epidural Analgesia for Labour<br/>Combined Spinal Epidural Analgesia for Labour<br/>Non-Neuraxial Techniques for Labour Analgesia<br/>Analgesia for Intrauterine Fetal Demise<br/>Category 4 Caesarean Delivery<br/>Spinal Anaesthesia for Caesarean Delivery<br/>Combined Spinal Epidural Anaesthesia for Caesarean Delivery<br/>Epidural TopUp for Caesarean Delivery<br/>General Anaesthesia for Caesarean Delivery<br/>Management of Spinal Anaesthesia Induced Hypotension during Caesarean Delivery<br/>Analgesia after Caesarean Delivery<br/>Anaesthesia for Manual Removal of Placenta<br/>Anaesthesia for Cervical Cerclage<br/>External Cephalic Version<br/>Artificial Rupture of Membranes<br/>Consent for Anaesthesia<br/>Documentation Standards for Anaesthesia<br/>Umbilical Cord Prolapse<br/>Expedited and Emergency Caesarean Delivery<br/>Operative Vaginal Delivery<br/>Massive Obstetric Haemorrhage<br/>Management of Uterine Atony<br/>Uterine Inversion<br/>Amniotic Fluid Embolus<br/>Vaginal Birth After Caesarean Delivery<br/>Shoulder Dystocia<br/>Normal Labour<br/>Cardiotocography<br/>Antenatal Monitoring<br/>Partogram<br/>Induction of Labour<br/>Augmentation of Labour<br/>Preterm labour and delivery<br/>Fetal malpresentations<br/>Placenta Praevia<br/>Placenta Accreta Syndrome<br/>Intrauterine Fetal Growth Restriction<br/>Multiple Gestation<br/>Preeclampsia and HELLP syndrome<br/>Cholestasis of Pregnancy<br/>Gestational Diabetes<br/>Venous Thromboembolism<br/>Obesity<br/>Peripartum Cardiomyopathy<br/>Complex Congenital Heart Disease in Pregnancy<br/>Thrombophilas<br/>Haemophilas<br/>Von Willebrand Disease<br/>Low molecular heparin, unfractionated heparin and neuraxial anaesthesia<br/>Accidental Dural Puncture<br/>Post Dural Puncture Headache<br/>Epidural Blood Patch<br/>Intrapartum Fever<br/>Failed Epidural Analgesia during Labour<br/>Failed Spinal Anaesthesia for Caesarean Delivery<br/>Management of Pain and Distress during Caesarean Delivery<br/>Backache after Neuraxial Anaesthesia<br/>Peripheral Nerve Lesions after Central Neuraxial Anaesthesia<br/>Spinal Cord Lesions after Neuraxial Anaesthesia<br/>Obstetric Nerve Palsies<br/>Reported Awareness under General Anaesthesia<br/>Neuraxial Anaesthesia after Previous Spinal Surgery<br/>Breastfeeding and Anaesthesia<br/>Difficult and Failed Intubation in Obstetric Anaesthesia<br/>Recognition and Management of High Spinal Anaesthesia<br/>Aspiration of Gastric Contents<br/>Local Anaesthetic Toxicity<br/>Anaphylaxis<br/>Malignant Hyperthermia<br/>Maternal Resuscitation<br/>Intrauterine Resuscitation<br/>Neonatal Resuscitation<br/>Anaesthetic Management of Pregnant Patients with Novel Coronavirus.

::Summary## Written for pathologists-in-training, this volume provides high-yield, at-a-glance summaries in a format that is easy to use. Rather than focus on organ-based histologic criteria, the text aids pathologic diagnosis, emphasizing immunohistochemistry, tumor syndromes, etc.

::Contents##<br/>Neurologic system<br/>Cardiovascular system<br/>Pulmonary system<br/>Gastrointestinal and urinary systems<br/>Renal system<br/>Endocrine system<br/>Hematologic and immune systems<br/>Drugs, doses, tables<br/>Labs<br/>Imaging<br/>Miscellaneous.

::Summary## For immediate, on-the-unit answers to ICU questions, get the must-have pocket guide: the fully updated "Quick Reference to Critical Care, 6th Edition". Covering a broad range of critical care topics, each chapter is divided by body system and alphabetically organized, addressing disease processes, disorders, medications and titration, tests, lab results, formulas, ICU equipment and treatment strategies and goals. Information provided is based on current, evidence-based procedures and stabilization practices. This classic, concise quick reference offers crucial guidance on numerous processes and procedures. -- From publisher's description.<br/>::Contents##<br/>Neurologic system<br/>Cardiovascular system<br/>Pulmonary system<br/>Gastrointestinal and urinary systems<br/>Renal system<br/>Endocrine system<br/>Hematologic and immune systems<br/>Drugs, doses, tables<br/>Labs<br/>Imaging<br/>Miscellaneous.

::Summary## This book focuses on quinoa, providing background information on its history, summarizing recent genetic and genomic advances, and offering directions for future research. Meeting the caloric and nutritional demands of our growing population will not only require increases in overall food production, but also the development of new crops that can be grown sustainably in agricultural environments that are increasingly susceptible to degradation. Quinoa is an ancient crop native to the Andean region of South America that has recently gained international attention because its seeds are high in protein, particularly in essential amino acids. Quinoa is also highly tolerant of abiotic stresses, including drought, frost and salinity. For these reasons, quinoa has the potential to help address issues of food security - a potential that was recognized when the United Nations declared 2013 the International Year of Quinoa. However, more effort is needed to improve quinoa agronomically and to understand the mechanisms of its abiotic stress tolerance; the recent development of genetic and genomic tools, including a reference genome sequence, will now help accelerate research in these areas.<br/>::Contents##<br/>Intro<br/>Preface to the Series<br/>Preface<br/>Compendium of Plant Genomes: Quinoa<br/>Contents<br/>Contributors<br/>Abbreviations<br/>1 History of the Quinuas in South America<br/>Abstract<br/>1.1 Origin<br/>1.2 Geographical Distribution<br/>1.3 Current Production Centers<br/>1.3.1 Colombia<br/>1.3.2 Ecuador<br/>1.3.3 Peru<br/>1.3.4 Bolivia<br/>1.3.5 Chile<br/>1.3.6 Argentina<br/>1.4 Main Types of Quinuas<br/>1.5 Research Advances<br/>1.6 Traditional Quinoa Utilization<br/>1.6.1 Preparation of the Llipt'a O (Llujt'a)<br/>1.6.2 Traditional Use of Leaves<br/>References 2 Botanical Context for Domestication in South America<br/>Abstract<br/>2.1 Introduction<br/>2.2 Quinoa Wild Ancestors and Relationships with Related Species<br/>2.3 Quinoa Genetic Structure<br/>2.4 Where and When Domestication Occurred<br/>2.4.1 Geographic Patterns of Variation in Genetic Variability<br/>2.4.2 Archaeological Evidence<br/>2.5 Traits Affected by Domestication<br/>2.5.1 Seed Size and Morphology<br/>2.5.2 Starch Forms<br/>2.5.3 Seed Shattering<br/>2.5.4 Plant Architecture<br/>2.5.5 Roots<br/>2.5.6 Climate Adaptation<br/>2.5.7 Aesthetic Selection<br/>2.5.8 Saponin Content 2.6 Geographical Distribution of the Domestication Syndrome. An Example in North West Argentina<br/>2.7 Concluding Remarks and Some Topics for Research<br/>References<br/>3 Botanical Context for Domestication in North America<br/>Abstract<br/>3.1 Introduction<br/>3.1.1 Ecological Context of C. berlandieri<br/>3.1.2 Molecular Studies of C. berlandieri<br/>3.1.3 Potential Diploid Progenitor Gene Pools of the ATGC in North America<br/>3.2 Descriptions of C. berlandieri Subspecies and Botanical Varieties<br/>3.2.1 C. berlandieri subsp. berlandieri var. boscianum 3.2.2 C. berlandieri subsp. berlandieri var. berlandieri<br/>3.2.3 C. berlandieri subsp. berlandieri var. macrocalycium<br/>3.2.4 C. berlandieri subsp. berlandieri var. sinuatum<br/>3.2.5 C. berlandieri subsp. berlandieri var. zschackei<br/>3.2.6 C. berlandieri subsp. jonesianum<br/>3.2.7 C. berlandieri subsp. nuttaliae<br/>3.3 Breeding Potential of C. berlandieri<br/>3.4 Conclusions<br/>References<br/>4 Quinoa Cytogenetics<br/>Abstract<br/>4.1 Genome Constitution of Polyploid C. Quinoa and Related Species<br/>4.2 Karyotype and Chromosome Banding<br/>4.3 Genome Size 4.4 Repetitive Sequence Organization and Evolution<br/>4.4.1 Tandem Repetitive Sequences<br/>4.4.2 Disperse Repetitive Sequences<br/>4.5 Chenopodium quinoa Is a Polysomatic Plant<br/>References<br/>5 A Chromosome-Scale Quinoa Reference Genome Assembly<br/>Abstract<br/>5.1 Introduction<br/>5.2 Quinoa Accession PI 614886<br/>5.3 Primary Sequencing by PacBio SMRT® Sequencing Technology<br/>5.3.1 PacBio SMRT Sequencing Technology<br/>5.3.2 Quinoa Genomic DNA Preparation and PacBio Sequencing<br/>5.4 Scaffolding of the Assembly with BioNano Genomics (Optical Maps)

::Summary## This classic, coauthored by New York Times columnist and pediatrician Dr. Perri Klass, has been fully revised and updated to reflect the recent significant changes in the recognition and care of children whose development doesn't go as expected. It includes new information about therapeutic interventions, managing co-morbidities, and getting support for children with developmental differences at school. Additional information covers community resources, initiatives at hospitals, clinics, and even theme parks, that make life easier for children with developmental differences and their families. The authors also offer a stronger focus on self-care for parents in this new edition, with the pediatrician's perspective of supporting families as they go through the diagnostic process over time.<br/>::Contents##<br/>Front Cover<br/>Title Page<br/>Copyright<br/>Dedication<br/>Contents<br/>Acknowledgments<br/>Introduction<br/>Part 1: A World of Quirky Kids<br/>What You Should Know<br/>Chapter 1. My Kid Is Different: Wondering and Worrying<br/>Chapter 2. Specialists, Labels, and Alphabet Soup: Diagnosis or Difference?<br/>Chapter 3. Understanding the Diagnosis: Grief and Loss and Moving Forward<br/>Part 2: Growing Up Quirky<br/>Literary Glimpses<br/>What You Should Know<br/>Chapter 4. Logistics of Everyday Life: The Home and the World<br/>Chapter 5. Family Life: Siblings, Parents, and Extended Family Chapter 6. Educating the Quirky Child: Every Year Is Different<br/>Chapter 7. Moving Through the School Years: Thriving and Learning in the Educational System<br/>Chapter 8. The Social Life of a Quirky Kid: Finding Friends and Making Connections<br/>Part 3: The Science, the Medical Science, and the Pseudoscience of Quirky Kids<br/>Literary Glimpses<br/>What You Should Know<br/>Chapter 9. Therapies: Finding Help and Evaluating the Help You Find<br/>Chapter 10. Medications and the Quirky Child: Drugs, Doses, and Daily Routines<br/>Chapter 11. Medical Perspectives on the Quirky Child: Questions and Answers Part 4: Looking Ahead<br/>Quirky Characters<br/>What You Should Know<br/>Chapter 12. Adolescence and Adulthood: Quirky Kids Grow Up<br/>Resources<br/>Index<br/>Back Cover

::Summary## This book delves into the biotechnological applications of Quorum sensing (QS)- a peculiar gene-regulatory process of some microorganisms. Quorum Sensing allows a large bacterial population to work together in a coordinated manner to carry out metabolic activities, which individual bacterium cannot. The different chapters describe how, associating bioremediation process with energy generation is an economical proposal, for reducing pollution and managing biowastes. The book discusses how QS can be exploited for biotechnological applications in generating bioproducts, bioenergy, bioremediation, biosensors, health and agricultural activities. It further highlights how QS is becoming an integral part of synthetic biology for genetic circuits for producing: (i) novel products, (ii) biosensors, (iii) bioactive molecules, etc. The book is divided into different sections for a clear understanding of the applicability of QS in, the Environment, Energy, Agriculture and Health sectors.<br/>::Contents##<br/>Intro; Dedication; Preface; Contents; About the Editor; Part I: Environment;<br/> 1: Quorum Sensing and Its Inhibition: Biotechnological Applications; 1.1 Introduction; 1.2 Biotechnological Applications of Quorum Sensing Systems; 1.2.1 Bio-energy; 1.2.2 Bioremediation; 1.2.3 Food and Health; 1.2.4 Detecting Metals and Pathogens; 1.2.5 Cancer Therapy; 1.2.6 Industrial Products; 1.2.7 Genetic Devices; 1.3 Biotechnological Applications of QSI; 1.3.1 Food Industry; 1.3.2 Aquaculture; 1.3.3 Health Care; 1.3.3.1 QSIs from Microbes; 1.3.3.2 QSIs of Plant Origin. 1.3.3.3 QSIs of Animal Origin1.3.4 Anti-biofouling; 1.3.5 Agriculture; 1.4 Synergism Between Antibiotics and QSIs; 1.5 Fais Attention à QSI; 1.6 Field Trials; 1.6.1 Protecting Plants; 1.6.2 Drinking Water; 1.6.3 Health Sector; 1.7 Opinion; References;<br/> 2: Talking Through Chemical Languages: Quorum Sensing and Bacterial Communication; 2.1 Introduction; 2.2 Acyl Homoserine Lactone (AHL) Based Quorum Sensing; 2.2.1 AHL-Based Signalling Molecules; 2.2.2 Signal Production; 2.2.3 Signal Recognition and Transduction; 2.3 Peptide Based Quorum Sensing. 2.3.1 Peptide Signalling Molecules2.3.2 Signal Production; 2.3.2.1 AgrD; 2.3.2.2 AgrB; 2.3.2.3 Mechanism of AIP Production; 2.3.3 Signal Recognition and Transduction; 2.3.3.1 AgrC; 2.3.3.2 AgrA; 2.4 Other Signalling Molecules; 2.4.1 Autoinducer 2 (AI-2); 2.4.2 DSF-Family; 2.4.3 PQS and IQS; 2.4.4 CAI-1; 2.4.5 DPO; 2.5 Conclusion; 2.6 Opinion; References;<br/> 3: Fundamentals of Bacterial Biofilm: Present State of Art; 3.1 Introduction; 3.2 Biofilm Structure; 3.3 Role of Biofilms in Microbial Communities; 3.3.1 Protection from Environment; 3.3.2 Nutrient Availability. 3.3.3 Acquisition of New Genetic Trait3.4 Factors Favoring Biofilm Formation; 3.4.1 Substratum Effect; 3.4.2 Conditioning Film; 3.4.3 Hydrodynamics; 3.4.4 Characteristics of Aqueous Medium; 3.4.5 Interaction of Bacterial Cells with Water Molecules; 3.4.6 Signaling System to Promote Biofilm Formation; 3.4.6.1 Quorum Sensing (QS); 3.4.7 Extracellular Polymeric Substances (EPS); 3.4.8 Role of eDNA; 3.5 Bacterial Adhesion- Steps Involved in Biofilm Development; 3.5.1 The Sessile Mode of Bacterial Growth; 3.5.2 Bacterial Glycocalyx In Vivo In Vitro. 3.5.3 Microcolony Formation by Adherent Bacteria3.5.4 Consortium Formation by Adherent Bacteria; 3.6 Occurrence of Bacterial Biofilm: Predominance in Aquatic System; 3.7 Physiology of Biofilm Population; 3.8 Effects of Material Properties on Bacterial Adhesion; 3.8.1 Surface Charge; 3.8.2 Surface Energy; 3.8.3 Roughness and Topography; 3.9 Measuring Biofilm; 3.10 Removal of Biofilms; 3.10.1 Removal of Biofilms; 3.10.2 Regulation of Biofilm Formation; 3.11 Conclusions; References;<br/> 4: Phylogenomics and Evolutionary Perspective of Quorum Sensing Regulators (LuxI/LuxR) in Prokaryotes.