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  • Book
    edited by Joshua Reineke.
    Contents:
    Historical overview of nanotechnology and nanotoxicology
    Characterization of nanomaterials for toxicological studies
    Methods for understanding the interaction between nanoparticles and cells
    Single-cell gel electrophoresis (comet) assay in nano-genotoxicology
    Single-cell nanotoxicity assays of superparamagnetic iron oxide nanoparticles
    Western blot analysis
    Application of reverse transcription-PCR and real-time PCR in nanotoxicity research
    Deriving TC(50) values of nanoparticles from electrochemical monitoring of lactate dehydrogenase activity indirectly
    Enzyme-linked immunosorbent assay of IL-8 production in response to silver nanoparticles
    Metabolomics techniques in nanotoxicology studies
    Nanoparticle uptake measured by flow cytometry
    Determining biological activity of nanoparticles as measured by flow cytometry
    Whole cell impedance biosensoring devices
    Free energy calculation of permeant-membrane interactions using molecular dynamics simulations
    Screening of fullerene toxicity by hemolysis assay
    Assessment of in vitro skin irritation potential of nanoparticles: RHE model
    In vivo methods of nanotoxicology
    The luminescent bacteria test to determine the acute toxicity of nanoparticle suspensions
    The primacy of physicochemical characterization of nanomaterials for reliable toxicity assessment: A review of the zebrafish nanotoxicology model
    Application of embryonic and adult zebrafish for nanotoxicity assessment
    Applications of subsurface microscopy
    Application of ICP-MS for the study of disposition and toxicity of metal-based nanomaterials
    Quantitative nanoparticle organ disposition by gel permeation chromatography
    Physiologically based pharmacokinetic modeling for nanoparticle toxicity study
    Biophysical methods for assessing plant responses to nanoparticle exposure
    In vivo nanotoxicity assays in plant models.
    Digital Access Springer 2012
  • Article
    Kreisel B, Conforti N, Gutnick M, Feldman S.
    Brain Res Bull. 1978 Nov-Dec;3(6):707-14.
    In view of the demonstrated role of light and of the suprachiasmatic nucleus (SCN) in the maintenance of circadian rhythms related to endocrine functions and as the mediobasal hypothalamus (MBH) controls neuroendocrine activity, the effects of light and MBH stimulation on the electrical activity of SCN neurons were studied in rats. Out of 253 cells studied in the SCN, 32 cells were antidromically activated, while 65 cells responded orthodromically to MBH stimulation. In another series of experiments out of 95 suprachiasmatic neurons, 11 were antidromically activated by MBH stimulation and 18 different SCN cells responded to continuous light. The present data, which demonstrate photic responses in suprachiasmatic neurons and direct projections from the SCN to MBH, are discussed in view of the current knowledge on the role of the retinohypothalamic tract and the SCN in the control of circadian rhythms.
    Digital Access Access Options