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- JournalDigital Access HathiTrust v. 1-22, 1902-16.
- ArticleMoran DM, Wheeler AW.Int Arch Allergy Appl Immunol. 1976;50(6):693-708.Glutaraldehyde modification was found to reduce the allergenic potency of crude timothy pollen extracts yet even highly substituted materials retained the capability of inducing the formation of allergen-specific antibody in animals. Experiments showed that these antibodies were capable of blocking skin test reactions to native timothy allergens in pollen-sensitive human volunteers. The value of glutaraldehyde-modified allergen extracts for use in desensitization vaccine therapy is discussed.