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  • Book
    Yasser El Miedany, editor.
    Summary: This book provides a comprehensive compilation of musculoskeletal ultrasonography (MSUS) fundamentals in pediatric rheumatology with emphasis on imaging techniques, normal anatomy, approaches towards standardization, and the spectrum of pathologic findings seen in the pediatric population. It examines the techniques and pitfalls of MSUS in pediatrics and compares sonoanatomy in pediatric patients versus adults. Chapters cover a range of anatomical sites, including shoulder and arm, elbow and forearm, wrists and hands, hip and thigh, knee and leg, and ankle and feet. The text also discusses the use of ultrasonography in juvenile inflammatory arthritic conditions and sports-related injuries. Finally, the book concludes with a summary of the recent advances in pediatric musculoskeletal ultrasonography. Featuring contributions from a large international group of leaders in the field, Pediatric Musculoskeletal Ultrasonography is an authoritative reference for pediatric and adult rheumatologists, sonographers, radiologists, physiotherapists, and orthopedic specialists.

    Contents:
    Chapter 1. Introduction to Musculoskeletal Ultrasonography
    Chapter 2. Pediatric Musculoskeletal Ultrasound: Pediatric Techniques and Applications
    Chapter 3. Standardized Musculoskeletal Ultrasound in Pediatric Rheumatology: Normal Age-Related Ultrasound Findings
    Chapter 4. Sonoanatomy
    Chapter 5. Imaging Approach and Tissue Pathology
    Chapter 6. Sononeurology: Individual Anatomic Sites and Clinical Applications
    Chapter 7. Shoulder (Including Arm)
    Chapter 8. Elbow (Including Forearm)
    Chapter 9. Wrist and Hand
    Chapter 10. Hip and Thigh
    Chapter 11. Knee (Including Leg)
    Chapter 12. Ankle and Foot
    Chapter 13. Neonatal and Infant Spine
    Chapter 14. Trauma and Sports Injury
    Chapter 15. Reporting Ultrasound Diagnosis and Findings
    Chapter 16. US Guided Interventional Procedures (Biopsy, Joint Procedures)
    Chapter 17. Advances in Pediatric Musculoskeletal Ultrasonography
    Chapter 18. Musculoskeletal US in Standard Clinical Practice: Disease Activity Monitoring, Cut Off Points, Disease Monitoring, Patient Education.
    Digital Access Springer 2020
  • Book
    Print [1990]
  • Article
    Jones KH, Langley PF, Lees LJ.
    Chemotherapy. 1978;24(4):217-26.
    Talampicillin is an ester of ampicillin which is readily hydrolysed on absorption to release ampicillin. It is well absorbed from the gastro-intestinal tract resulting in a greater bioavailiability of ampicillin than can be achieved with equivalent doses of ampicillin itself. Dose response studies have confirmed a direct relationship between the dose of talampicillin administered and peak serum ampicillin concentration and urinary excretion of ampicillin. Dosing of ampicillin after food has been shown to adversely affect the total bioavailability of ampicillin. This is not so after dosing with talampicillin. The bioavailability of ampicillin from a 250-mg Talpen tablet dosed after a large meal was significantly greater than that from 250 mg ampicillin dosed in the fasting state. Studies in volunteer subjects at multiples of the proposed therapeutic dose for periods of up to 28 days have indicated its acceptability, bioavailability and lack of side effects on repeated dosing. The fate of the phthalidyl moiety of talampicillin has been investigated in repeated dose studies and in a single dose studies and in a single dose study in which radiolabelled talampicillin was administered. The principal metabolite of the phthalidyl moiety in man has been shown to be 2-hydroxymethylbenzoic acid, which is identical to that in experimental animals used for toxicological investigations.
    Digital Access Access Options