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- ArticleVestergaard P.Acta Endocrinol Suppl (Copenh). 1978;217:11-75.After a brief summary of the biosynthesis, production rates, metabolism and elimination of the pertinent adrenocortical and gonadal precursors for the common urinary neutral steroids, a survey is presented of the general, disease related and hormonal factors that can affect the excretion of neutral steroids in urine.