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  • Book
    Aaron Miller, editor.
    Contents:
    Multiple sclerosis: an overview
    The pathophysiology and clinical presentation of multiple sclerosis
    Assessment and diagnosis of relapsing multiple sclerosis
    Treatment strategies in multiple sclerosis
    Emerging therapies in multiple sclerosis
    Symptom management in multiple sclerosis.
    Digital Access Springer 2017
  • Article
    Strobel R, Wöhrmann K.
    Biochem Genet. 1977 Dec;15(11-12):1015-21.
    Competition experiments were carried out under varying exogenic and endogenic conditions. The genotypes were marked by combinations of two esterase loci, each with two alleles. When genotypes of the line W7 were used, there was no demonstrable influence of the gene blocks marked by the Est-1 locus on the competitive ability at temperatures of 21 and 29 C. However, genotypes carrying the fast allele of the Est-2 locus were favored. At 38 C, the outcome of the competition was reversed. The defined gene blocks showed different effects when interacting with different genetic backgrounds (line M7). Genotypes marked by the slow allele of the Est-2 locus were now favored (21 and 29 C), and even the gene blocks marked by the alleles of the Est-1 locus influenced the genotypes' competitive abilities. Again, the results were partly reversed at 38 C. The results are discussed with regard to the importance of enzyme variants for the genotypic selection value.
    Digital Access Access Options