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  • Book
    Stephen M. Stahl ; Nancy Muntner, illustrations ; Sara Ball, editor.
    Contents:
    Pain affects us all
    Neurobiology of pain
    The "pain patient"
    Pain disorders
    Pain drugs
    Monitoring and caring for patients in pain.
    Digital Access Cambridge 2009
  • Article
    Bourguignon JP, Franchimont P.
    Acta Endocrinol (Copenh). 1977 Sep;86(1):15-24.
    Highly specific and sensitive radioimmunological methods were applied to determine the levels of LH-RH like immunoreactivity in urine previously extracted by spherosil and methanol, and to assay the gonadotrophins, after extraction with acetone. The endogenous urinary LH-RH like immunoreactivity material was identified by chromatography on Sephadex G25, as having physicochemical properties similar to those of the hormone found in unextracted urine after iv injection of synthetic LH-RH, but different from those of the synthetic decapeptide. The LH-RH like immunoreactivity and the gonadotrophins were assayed in daily collected urine during the reproductive cycle of 3 normal women. A midcycle peak of both FSH and LH was found in each subject. No increases of LH-RH like immunoreactivity were found before or concomittant with the gonadotrophins surge. But peaks of urinary LH-RH like immunoreactivity were observed during the luteal phase, without subsequent increase of gonadotrophin secretion.
    Digital Access Access Options