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- ArticleGancedo JM, Clifton D, Fraenkel DG.J Biol Chem. 1977 Jul 10;252(13):4443-4.Using yeast mutants, it is shown that growth on glucose occurs even in the absence of both hexokinase A and hexokinase B; fructose growth requires at least one of these two enzymes. Expression of hexokinase A and of glucokinase seem to be regulated.