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  • Book
    Cong-Qiu Chu.
    Summary: This book provides an overview of the discovery and structure of IL-17, including its pathogenesis and role in chronic inflammation and autoimmunity. To capture the latest developments and product approvals the book also discusses the therapeutic advances and looks at emerging therapies targeting the IL-17 pathway. IL-17 is a pro-inflammatory cytokine that has a key role in inflammation, autoimmunity, and host defense in a number of inflammatory disorders such as rheumatoid arthritis, psoriatic arthritis and psoriasis, ankylosing spondylitis, multiple sclerosis, and inflammatory bowel disease. The discovery of the IL-17-Th17 pathway has seen exciting development in the field of immunology and inflammation research, which has led to a number of recent regulatory approvals.

    Contents:
    Introduction
    Overview of IL-17 family.-Il-17 in host defense
    Th17 cells: differentiation and regulation
    The role of the IL-17/Th17 pathway in the pathogenesis of autoimmune inflammatory diseases
    Therapeutic applications: strategies and molecules targeting the IL-17/Th17 pathway
    Concluding remarks.
    Digital Access Springer 2017
  • Article
    Klagsbrun M, Davis DI.
    Fam Process. 1977 Jun;16(2):149-73.
    The authors propose that substance use and abuse may be understood and effectively treated when the individual user or abuser is viewed in the context of his family or stable living group. This viewpoint attributes an important role in the maintenance of individual substance abuse to interactional processes within the family system. The theoretical assumptions implied by this viewpoint are discussed. A selective literature review examines the available evidence, from both experimental and clinical-descriptive studies, that is relevant to this proposal. The next step toward a more systematic investigation of these ideas is outlined, including testable hypotheses, methodological issues and problems, and potentially useful techniques.
    Digital Access Access Options