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  • Book
    Gaetano Santulli, editor.
    Contents:
    1. A fleeting glimpse inside microRNA, epigenetics and micropeptidomics
    2. The microRNA machinery
    3. microRNAs in mitochondria: an unexplored niche
    4. microRNAs distinctively regulate vascular smooth muscle and endothelial cells: functional implications in angiogenesis, atherosclerosis, and in-stent restenosis
    5. Mechanistic role of microRNAs in coupling lipid metabolism and atherosclerosis
    6. microRNAs in pancreatic β-cell physiology
    7. microRNA and cardiac regeneration
    8. microRNAs and endometrial pathophysiology
    9. microRNA and NF-kappa B
    10. microRNAs: key players in hematopoiesis
    11. Regulatory roles of miRNAs in aging
    12. Computational prediction of microRNA targets
    Digital Access Springer 2015
    Access via Advances in experimental medicine and biology ; 2015; 887
    Location
    Version
    Call Number
    Items
    Advances in experimental medicine and biology ; 2015; 887
    2015
  • Article
    Fass RJ, Ruiz DE, Gardner WG, Rotilie CA.
    Arch Intern Med. 1977 Jan;137(1):28-38.
    Thirty-eight adult patients with serious pleuropulmonary, soft-tissue, bone, and intra-abdominal infections caused by combinations of aerobic, facultative, and anaerobic bacteria were treated with parenterally given clindamycin phosphate and gentamicin sulfate and surgery when appropriate. Nine had associated bacteremia. In 29, infections failed to respond to other therapeutic regimens, which included penicillins, cephalosporins, aminoglycosides, and chloramphenicol. Results with clindamycin and gentamicin were excellent and were attributed primarily to the activity of clindamycin against anaerobes, particularly Bacteroides fragilis. Serum concentrations of clindamycin surpassed by manyfold the minimal inhibitory concentrations (MICs) for anaerobes. Serum concentrations of gentamicin did not consistently surpass the MICs for Enterobacteriaceae and Pseudomonas aeruginosa, although those organisms were consistently gentamicinsusceptible by disk diffusion susceptibility tests. Persistent colonization with Enterobacteriaceae, P aeruginosa, enterococci, or Candida were common, and occasionally they were significant in prolonging the clinical courses of patients with extensive infections.
    Digital Access Access Options