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  • Book
    Fong Yuman, Pier Cristoforo Giulianotti, Jason Lewis, Bas Groot Koerkamp, Thomas Reiner, editors.
    Contents:
    Basis of practice
    Lighting in the Operative Room: Current Technologies and Considerations
    Modalities for Intraoperative Imaging
    Fluorescents Probes
    Detectors for Intraoperative Molecular Imaging: From Probes to Scanners
    Isotopes and Procedural Imaging
    Radiologically Imageable Nanoparticles
    Flat Panel CT and the Future of OR imaging and Navigation
    Cerenkov Luminescence Imaging
    Organ Deformation and Navigation
    Clinical Milestones for Optical Imaging
    3D in the Minimally Invasive Surgery (MIS) Operating Room: Cameras and Displays in the Evolution of MIS
    Molecular Tumor Marker Recognition: Nanotechnology for On-Line Diagnostics in the OR
    Ultra Small Fluorescent Silica Nanoparticles as Intraoperative Imaging Tools for Cancer Diagnosis and Treatment
    Image Processing Technologies for Motion Compensation
    Current Clinical Applications
    Near Infra-red Imaging in Robotic Surgery
    New Preoperative Images, Surgical Planning and Navigation
    New Generation Radiosurgery
    Breast Lesion Localization
    Intraoperative Breast Imaging and Image-Guided Treatment Modalities
    Sentinel Lymph Node Mapping: Current Practice and Future Developments
    Narrow Band Cystoscopy
    Fluorescence Imaging of Human Bile and Biliary Anatomy
    PET Guided Interventions from Diagnosis to Treatment.
    Digital Access Springer 2015
  • Article
    Commissiong JW, Sedgwick EM.
    Eur J Pharmacol. 1979 Jul 15;57(1):83-92.
    The effects of L-DOPA and 5-HTP on the tonic stretch reflex (TSR) in the decerebrate rat were studied. L-DOPA facilitated the TSR in a dose-dependent manner. The facilitation of the TSR was blocked by pimozide. A sensitive electromygraphic (EMG) technique capable of recording single motor unit discharges was used. The EMG results suggest that gamma motoneuron sensitivity was increased to a greater degree than alpha motoneuron sensitivity during the facilitation by L-DOPA. The L-DOPA-induced facilitation persisted in animals partly depleted of 5-hydroxytryptamine (5-HT) by reserpine, p-chlorophenylalanine or 5,6-dihydroxytryptamine. 5-HTP inhibited the TSR in a dose-dependent manner. It is concluded that DA not 5-HT is the amine which normally mediates facilitation of the TSR after L-DOPA and that gamma motoneuron activation is more likely to be involved to a greater degree than alpha motoneuron activation in the neural mechanisms of the facilitation.
    Digital Access Access Options