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- BookNima Rezaei, editor.Contents:
Specific Organ Tumors: General Considerations On Immunotherapy
Vaccination Of Human Solid Tumors: Recent Progress In The Clinical Setting
Immunotherapy For Pediatric Solid Tumors
Immunopathology Of Hematological Cancers And Immunotherapy Of Leukemia And Multiple Myeloma
Immunopathology Of Lymphoma And Immunotherapy Of Hodgkin's Disease And Non-Hodgkin's Lymphoma
Cancer-Testis Antigens As Targets For The Immunotherapy Of Hematological Malignancies
Tumor Immunology And Immunotherapy Of Gastrointestinal Tract Cancers
Immunology And Immunotherapy Of Colorectal Cancer
Immunopathology Of Hepatobiliary Tumors And Immunotherapy Of Liver Cancers
Immunology And Immunotherapy Of Pancreatic Tumors
Immunology Of Cutaneous Tumors And Immunotherapy For Melanoma
Immunopathology Of Head And Neck Tumors And Immunotherapy Of Squamous Cell Carcinoma
Immunopathology And Immunotherapy Of Oral Cancers
Immunopathology Of Bone And Connective Tissue Cancers And Immunotherapy Of Sarcomas
Immunopathology Of Central Nervous System Cancers And Immunotherapy Of Brain Tumors
Immunology And Immunotherapy Of Pulmonary Tumors
Immunopathology Of Urinary System Cancers And Immunotherapy Of Renal And Bladder Cancers
Immunopathology Of Cancers Of Male And Female Genitalia Organs And Immunotherapy Of Cervical And Prostate Cancer
Immunology And Immunotherapy Of Ovarian Cancer
Revisiting Immunology For Breast Cancer
Immunology And Immunotherapy Of Graft Versus Host Disease.Digital Access Springer 2015 - ArticleScadding GK, Thomas HC, Havard CW.Clin Exp Immunol. 1979 May;36(2):205-13.Thymus-derived (T) lymphocytes in the peripheral blood and cellular immune function have been studied in ten patients with myasthenia gravis and in fifteen different myasthenic patients more than 10 years after thymectomy. The results were compared with those of a normal control population. The non-thymectomized myasthenic patients had normal T lymphocyte concentrations measured by rosetting with native sheep red cells. These patients also showed normal sensitization and recall of delayed hypersensitivity, phytohaemagglutinin (PHA) induced lymphocyte transformation and antibody-assisted (K cell) cytotoxicity; however, PHA-induced cytotoxicity was markedly reduced (P less than 0.001). The thymectomized group exhibited a lower mean percentage and absolute number of E-rosette-forming cells, which returned toward normal after in vitro treatment with thymosin. PHA-induced lymphocyte cytotoxicity, however, was normal in the patients who had undergone thymectomy, as were lymphocyte transformation, antibody-assisted cytotoxicity and sensitization to dinitrochlorobenzene (DNCB); there was a decrease in recall of established delayed hypersensitivity. Adult thymectomy in man, therefore, produces a partial and dissociated decrease in T cell responses and it is unlikely that the beneficial effect of this operation in myasthenia gravis is related to immunosuppression.