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  • Book
    George H. Sakorafas, Vassileios Smyrniotis, Michael G. Sarr, editors.
    Summary: This book provides a thorough overview of the detection of PCNs using modern imaging techniques and a clear guide to the recognition of the different subtypes of PCN based on their radiologic and histopathologic features. This volume will serve as an excellent aid to the selection of optimal therapeutic strategies based on preoperative diagnosis. A further important feature is the emphasis placed on radiologic, clinical, and surgical correlations. Pancreatic cystic neoplasms (PCNs) have been increasingly recognized during the past decade, mainly because of the widespread use of modern imaging modalities for the investigation of often unrelated abdominal symptoms. The three most common subtypes of PCN are serous cystic neoplasms, mucinous cystic neoplasms, and intraductal papillary mucinous neoplasms. These subtypes have distinct radiologic and histopathological features, and their biological behavior differs greatly. Accurate preoperative diagnosis is of prime importance in selecting the optimal therapeutic strategy: while serous cystic neoplasms are almost always benign, and may be treated conservatively, mucinous cystic neoplasms and intraductal papillary mucinous neoplasms have malignant potential, warranting an aggressive surgical approach, i.e., pancreatectomy. Pancreatic Cystic Neoplasms will be of great interest to surgeons, gastroenterologists, radiologists, oncologists, and pathologists, and also to internists and residents in these specialties.

    Contents:
    Introduction
    Classification
    Serous cystic neoplasms
    Mucinous cystic neoplasms
    Intraductal Papillary Mucinous Neoplasms
    Rare cystic neoplasms
    Diagnostic evaluation
    Imaging
    Cross sectional Imaging
    US, CT, MRI
    Endoscopic ultrasonography
    ERCP / MRCP
    Intraductal ultrasonography / ductoscopy
    FNA and analysis of the cystic fluid
    Cytology
    Biochemical analysis
    Treatment
    Indications for surgery
    Surgical treatment
    Adjuvant therapy
    Follow-up
    Prognosis.
    Digital Access Springer 2015
  • Article
    Klobusická M, Kalafut F, Novotná L.
    Neoplasma. 1978;25(6):667-77.
    The authors have studied the influence of primary, methylcholanthrene-induced tumor on T and B lymphocytes of spleen, thymus, draining lymph nodes and peripheral blood of rats. Differences in weight of tumors were found to correlate with changes in proportionality of T and B lymphocytes of followed organs. Small tumors induced but insignificant changes. There was increased trapping of T lymphocytes in spleen and lymph nodes with simultaneous decrease in peripheral blood. The authors noted a high percentage of blasts. B lymphocytes showed a tendency to compensate for the loss of T cells. Large, progressively growing tumors caused evident exhaustion in the number of both cell types in lymph nodes and peripheral blood. In the spleen there was slower exhaustion. Reduction in the number of B lymphocytes correlated with the size of tumor. Blasts disappeared. Proportionality of T and B lymphocytes in thymus did not appear to be influenced by the size of tumor.
    Digital Access Access Options