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  • Book
    editors, Giampietro Corradin, Howard Engers.
    Contents:
    Malaria vaccine development : over 40 years of trials and tribulations / Giampietro Corradin & Howard Engers
    Malaria vaccines : reflections on 40 years of basic research and translation applications / Giampietro Corradin
    Challenges for the stakeholders / Howard Engers
    Plasmodium vivax vaccine surrogate markers of protection : dawning of a new era / Mary R. Galinski, Rabindra M. Tirouvanziam & Alberto Moreno
    Plasmodium vivax vaccine development in Colombia : advances and challenges / Myriam Arevalo-Herrera & Sócrates Herrera-Valencia
    Progress towards development of a vaccine for Plasmodium vivax malaria / Ahmad Rushdi Shakri & Chetan E. Chitnis
    Correlates of protection for Plasmodium falciparum malaria vaccine development : current knowledge and future research / James G. Beeson, Freya J.I. Fowkes, Linda Reiling, Faith H. Osier, Damien R. Drew & Graham V. Brown
    Plasmodium falciparum RTS,S vaccines and future development / Tom Egwang
    Plasmodium falciparum pre-erythrocytic vaccines : previous experience and the challenge of selecting new candidates / Thomas L. Richie & Joanne M. Lumsden
    Plasmodium falciparum whole-parasite malaria vaccines / Else M. Bijker & Robert W. Sauerwein
    Index.
    Digital Access Future Med 2014
  • Article
    Wise WC.
    J Cell Physiol. 1978 Nov;97(2):161-7.
    We have examined the transport of amino acids by the sodium-dependent "A" and "ASC" system in thymic- and splenic-derived lymphocytes from the Long-Evans rat. Lymphocytes derived from the thymus transport amino acids by both the "A" and "ASC" systems, whereas lymphocytes from the spleen transport amino acids by the "ASC" system only. Thymic lymphocytes are capable of establishing a steady state distribution ratio of 7.9 for 2-aminoisobutyric acid, but splenic lymphocytes can attain only 3.5. The steady state distribution ratio of alanine was the same in both cell types. Sodium-independent transport is also different in splenic and thymic lymphocytes. But both cells move amino acids by a Na+-independent system for mediated exchange-diffusion. The studies show that lymphocytes derived from the spleen and thymus transport amino acids differently, and that the "T" lymphocytes from the spleen have membrane transport systems different from "T" lymphocytes from the thymus.
    Digital Access Access Options