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- BookStanley B. Prusiner.Contents:
Growing up
The beginning of an odyssey
A plethora of theories
The scrapie race
Dr. America and the trembling cannibals
The battle for tenure
What's in a name?
Lost in the Pacific fog
The amyloid story
Finding the gene
Jousting with the press
Deciphering human prion diseases
What's in a shape?
Turf battles
Mad cow and other prion strains
Stockholm
The third judgment of Paris
Epilogue : the quest for therapeutics. - ArticleHarkess NK, Murray ML.Antimicrob Agents Chemother. 1978 May;13(5):802-8.Examination of Haemophilus influenzae strains isolated in New Orleans revealed ampicillin-resistant strains with plasmids of size classes not previously detected in North America. The molecular weight of plasmids in five ampicillin-resistant strains ranged from 0.8 x 10(6) daltons (0.8 Mdal) to 36 Mdal. The molecular weights of the plasmids were determined by sucrose gradient centrifugation, electron microscopy, and agarose gel electrophoresis. Plasmids of the previously detected 30-Mdal size class were found in three of the five ampicillin-resistant strains. Restriction enzyme analysis is consistent with a close relationship between these three 30-Mdal plasmids. Of the two remaining ampicillin-resistant strains, one contained a single plasmid of 36 Mdal and the other contained two plasmids of 0.8 and 2.3 Mdal.