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  • Book
    edited by Demetris Papamichael, Riccardo A. Audisio.
    Summary: The risk of cancer increases with age and the number of older adults seeking treatment is rising dramatically in line with the aging population. The care of older patients differs from that of younger adults because of variation in the biology of the tumor, age-related variation in host physiology, co-morbidity burden and psychosocial issues, which might impact the efficacy and side effects of cancer therapy. Management of Colorectal Cancers in Older People focuses on treatment strategies of colorectal cancers and provides guidance on the issues specific to older patients, spanning background and epidemiology, special considerations in the care of older people, therapeutics, and psychosocial considerations. This book offers a thorough review of current approaches to treating older colorectal cancer patients, detailing the special issues and considerations involved. The discipline-spanning coverage outlines best practice and proposes topics for future research. The third volume in the Management of Cancer in Older People series, this book will be of interest to all surgical oncologists, medical and radiation oncologists, gerontologists, proctologists and other members of the multidisciplinary team involved in the care of elderly colorectal cancer patients.

    Contents:
    The Epidemiology of Colorectal Cancer in Older Patients
    Genetic Alterations in Colorectal Cancer in Older Patients
    Comorbidity, Disability, and Geriatric Syndromes
    CRC: Diagnosis, Staging, and Patient Assessment
    Comprehensive Geriatric Assessment
    Surgical Treatment of Colorectal Cancer in Older Patients
    Palliative Surgical Approaches for Older Patients with Colorectal Cancer
    Surgery for Liver Metastases
    Rectal Cancer Radiotherapy and Older Patients: Evidence-Based or Opinion-Based Treatment?
    Adjuvant Therapy of Colorectal Cancer in Older People
    Chemotherapy in the Metastatic Setting
    Targeted Therapies in Older Patients with Metastatic Colorectal Cancer
    Palliation and Quality of Life.
    Digital Access Springer 2013
  • Article
    Lavine LS, Lustrin I, Shamos MH.
    Clin Orthop Relat Res. 1977 May(124):69-74.
    Bone possesses a bioelectric property that is important in maintaining its structural and architectural integrity. In vivo experiments demonstrate that bone formation can be accelerated by the application of direct current. We hypothesize that bone formation occurs through an electrochemical rather than an electromechanical effect. Two cases of congenital pseudarthrosis of the tibia treated by direct current stimulation are presented. A bone graft may be added to enhance bony union in conjunction with direct current. The implications of this work are that there is need for further fundamental studies including ultrastructural observations.
    Digital Access Access Options