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  • Book
    volume editor, Tetsuo Shiohara.
    Contents:
    Atopic dermatitis and the hygiene hypothesis revisited / Flohr, C., Yeo, L.
    Loss-of-function mutations within the filaggrin gene predispose to atopic dermatitis / Kawasaki, H. ... [et al.]
    Fc epsilon R1-toll-like receptor interaction in atopic dermatitis / Novak, N., Bieber, T.
    The antimicrobial skin barrier in patients with atopic dermatitis / Schittek, B.
    Defective sweating responses in atopic dermatitis / Shiohara, T., Doi, T., Hayakawa, J.
    The role of cytokines/chemokines in the pathogenesis of atopic dermatitis / Yamanaka, K., Mizutani, H.
    Contribution of interleukin 18 to the development of infection-associated atopic dermatitis / Tsutsui, H., Mizutani, H., Nakanishi, K.
    Innate immunity in atopic dermatitis / Mrabet-Dahbi, S., Maurer, M.
    The role of regulatory T cells in atopic dermatitis / Agrawal, R., Wisniewski, J., Woodfolk, J.A.
    Increased susceptibility to cutaneous viral infections in atopic dermatitis : the roles of regulatory T cells and innate immune defects / Shiohara, T. ... [et al.]
    Biomarkers for itch and disease severity in atopic dermatitis / Lee, C.-H., Yu, H.-S.
    Practical issues on interpretation of scoring atopic dermatitis : SCORAD index, objective SCORAD, patient-oriented SCORAD and three-item severity score / Oranje, A.P.
    Systemic therapy of atopic dermatitis in children and adults / Simon, D.
    Digital Access Karger 2011
  • Article
    Liew FY.
    Eur J Immunol. 1977 Oct;7(10):714-8.
    Mice injected with 1 X 10(8) sheep red blood cells (SRBC) into the footpad showed high levels of delayed-type hypersensitivity (DTH) to SRBC 4-8 days after the injection. In contrast, mice injected intravenously with 1 X 10(9) SRBC were unresponsive to DTH induction through 1 X 10(8) SRBC injected into the footpad. This suppression of DTH was maintained for at least 6 weeks and was transferable spleen, lymph node and thymus cells to normal syngeneic recipients. Bone marrow cells, on the other hand, did not contain the suppressor cells. The suppression of DTH was antigen-specific in that DTH to chicken red blood cells and contact sensitivity to 2,4-dinitrofluorobenzene was not affected. The suppressor cells were theta-positive and Ig-negative. They appeared in the spleen in optimum number 3-4 days after induction. The suppressor cells affected both the induction and manifestation of DTH. The presence of suppressor and effector cells for DTH inducible by different routes of antigenic presentation reflects the dynamic balance in the regulation of DTH.
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