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- Bookedited by Hans Peter Soyer, Michael Binder, Anthony C. Smith, Elisabeth M.T. Wurm.Contents:
Introduction to Teledermatology
Historical Review
Medical Prerequisites
Technical Prerequisites
Photographic Imaging Essentials
Performance of Teledermatology including Clinical Examples
Teledermatology in Underdeveloping Countries
Special Methods of Teledermatology
Teledermatology and Reflectance Confocal Microscopy Quality Assurance
Legal Assumptions
Economic Aspects and Cost-effectiveness
Future Horizons
APPENDIX: Education and Training Opportunities
Quality Certificate Teledermatology
Sample Protocol, Consent Form and Information Sheet
References and Relevant Web links
Glossary
Subject Index.Digital Access Springer 2012 - ArticlePilarski LM, Bretscher PA, Baum LL.J Exp Med. 1977 May 01;145(5):1237-49.Concanavalin A stimulation of T-cell cytotoxicity has been shown to be absolutely dependent on helper T-cell collaboration. Thymocytes stimulated with ConA do not differentiate to yield cytotoxic effector cells. However, thymocytes cocultured with irradiated spleen cells as helpers and ConA yield high levels of cytotoxicity. The helper cell bears theta antigens on its surface, is not an adherent cell, and does not require any adherent cell functions in our culture conditions. The ConA-dependent helper cells appear to be polyclonal in specificity. Thus, polyclonal stimulation of cytotoxicity by ConA requires T helper-T precursor collaboration in analogy to antigen-specific T helper-T precursor interactions. Unlike the antigen-specific interacitons, the ConA-driven cytotoxicity does not appear to require linked associative recognition for induction of cytotoxicity.