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  • Book
    edited by Mary A. Williamson with L. Michael Snyder.
    Contents:
    Introduction to laboratory medicine / Rao
    Laboratory tests
    Laboratory cultures
    Cardiovascular diseases / Vallaro & Pechet
    Central nervous system disorders / Szakacs
    Digestive diseases / Snyder
    Endocrine diseases / Yu
    Genitourinary diseases / Pechet & Kiefer
    Gynecologic and obstetric disorders / Pechet
    Hematologic diseases / Pechet
    Hereditary and genetic diseases
    Immune and autoimmune disorders / Pechet
    Infectious diseases / Mitchell
    Miscellaneous / Snyder
    Respiratory, metabolic, and acid-base disorders / Rao
    Toxicology and therapeutic drug monitoring / Jenkins.
    Digital Access Ovid 2011
  • Article
    Nagata S.
    Cell Tissue Res. 1977 Mar 30;179(1):87-96.
    Sequential electron microscopic observations of thymic histogenesis in the toad, Xenopus laevis, reveal that the thymus arises as epithelial buddings of the visceral pouches at Nieuwkoop-Faber stage 40, and acquires its basic histological features at stages 48-49. In the rudiments and the surrounding mesenchyme at stages 43-45, there are non-epithelial cells with pseudopodia, abundant ribosomes, and marginated heterochromatin. These cells, possible precursor cells of thymic lymphocytes, are frequently observed to attach and pass through the basal lamina which coats the thymic rudiment. The proliferation and differentiation of large lymphocytes are evident at stage 47. During stages 48-49 the small lymphocytes, lymphoid cortex and epithelial medulla including the thymic cysts, differentiate, and vascularization occurs. The results provide an ultrastructural basis for recent experimental evidence that the thymus exerts its essential function at stages 47-48. The possibility of non-epithelial derivation of thymic lymphocytes is discussed.
    Digital Access Access Options