Search
Filter Results
- Resource Type
- Article1
- Book1
- Book Print1
- Print1
- Article Type
- Research Support, U.S. Gov't, Non-P.H.S.1
- Result From
- Lane Catalog1
- PubMed1
-
Year
- Journal Title
- J Biol Chem1
Search Results
Sort by
- ArticlePeters T, Feldhoff RC, Reed RG.J Biol Chem. 1977 Dec 10;252(23):8464-8.Antigenic properties of 14 fragments of bovine albumin were measured using antisera to albumin and to two of its fragments. All seven fragments larger than 21,000 daltons formed immune precipitates. Although immune precipitates were not formed with smaller fragments, inhibition tests indicated the presence of antigenic sites on several of these fragments as well. The results predict the occurrence of six or more antigenic determinants and allow assignment of their positions in the parent molecule. These sites are distributed along the entire protein chain, with the sites of greatest antibody affinity situated in the COOH-terminal region. Evidence is presented that some sites are homologous, reacting with the same populations of antibodies, and that other sites are unique, binding to an exclusive population of antibodies.
- BookHartmann, Ph. Karl; Wimmer, Franz.PrintLocationVersionCall NumberItemsRB100 .H333 18281