Bookeditor, Giovanna Zinzalla.
Contents:
Understanding and exploiting protein-protein interactions as drug targets / Giovanna Zinzalla
Protein-protein interactions : an emerging class of molecular targets for anticancer drugs / Alex W. White, Jitka Soukupová & Andrew D. Westwell
Druggability of protein-protein interactions / Veronique Hamon & Xavier Morelli
Chemical library screening approaches to aid the design of protein-protein inhibitors / Luca Laraia & David R. Spring
Peptides as protein-protein interaction modulators / Erika Nieddu, Luisa Merello & Carlo Bidoia
Constrained peptide helices / Andrew B. Mahon & Paramjit S. Arora
Synthesis of peptidomimetic scaffolds / Andrew J. Wilson
Computational approaches for the design of protein-protein interaction inhibitors / Wenbo Yu, Olgun Guvench & Alexander D. MacKerell Jr.
Biochemical assays and biophysical tools for inhibitor identification and validation / Adrian Fowkes, Helene Bertrand & Geoff Wells
Cell-based assays for identifying, validating and optimizing protein-protein interaction modulators / Abigail L. Male & Ali Tavassoli
Future directions / Alexander L. Breeze
Index.