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  • Book
    Bruce E. Onofrey, Leonid Skorin Jr, Nicky R. Holdeman.
    Summary: "Offering concise, easy-access information for the most common ocular problems, Ocular Therapeutics Handbook: A Clinical Manual is a proven, practical resource for optometrists, nurses, and primary care physicians. A consistent outline format and numerous algorithms make vital information easy to retrieve, while a problem-oriented approach provides a real-world perspective and helps build critical thinking skills. The revised 4th Edition includes an accompanying eBook that contains all of the content in the book, plus additional clinical photographs, illustrations, and surgical and procedural videos."--Publisher
    Digital Access Ovid 2020
  • Article
    Baraona E.
    Leber Magen Darm. 1978 Oct;8(5):271-7.
    An early manifestation of alcoholic liver injury is the accumulation of protein, as well as fat, in the liver. The increase in soluble proteins is associated with retention of water and swelling of the hepatocyte, resulting in hepatomegaly. Though "in vitro" ethanol inhibits hepatic protein synthesis, no consistent effects have been found after acute alcohol administration "in vivo". Moreover, after chronic alcohol consumption, the synthesis of liver protein is increased rather than decreased. Alcohol consumption, however, delays the secretion of proteins from the liver into the plasma, promoting accumulation in the liver of proteins which are primarily destined for export. The altered secretion is associated with decreased hepatic content of polymerized tubulin and visible disruption of microtubules, an organelle which may maintain the architectural organization required for transport of macromolecules. The alteration of microtubules has been linked to consequences of ethanol oxidation in the liver.
    Digital Access Access Options