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  • Book
    Kjetil Søreide, Stefan Stättner, editors.
    Summary: This textbook provides a practically applicable resource for understanding the surgical oncology management of pancreatic cancer. It discusses relevant aspects of anatomy and pathophysiology along with the latest diagnostic techniques. Insightful descriptions are then provided detailing how to perform critical surgical procedures when treating these patients. Relevant perioperative management strategies and emerging themes in cancer biology critical to understanding and treating the disease are also described. The need for cross-discipline collaboration to facilitate and enhance innovation within the discipline is reinforced throughout the text. Each chapter presents the relevant current clinical standards along with areas of controversy in both research and clinical practice within "pearls and pitfalls" sections. Textbook of Pancreatic Cancer: Principles and Practice of Surgical Oncology is a detailed work covering the basic material important to trainees as well as advanced curriculum for established specialists in the field from a multi-disciplinary perspective. Therefore, it is crucial resource for all practicing and trainee professionals who encounter these patients in their day-to-day clinical practice. .

    Contents:
    Intro
    Foreword
    Foreword from ESSO
    Foreword from the President of IHPBA
    Foreword from the President of the AHPBA
    Preface
    Contents
    Contributors
    Part I: Pancreatic Cancer Disease Burden
    Chapter 1: Risk Factors for Pancreatic Cancer
    1.1 Introduction
    1.2 Age, Gender and Race
    1.3 Pancreatitis (Acute, Chronic and Hereditary)
    1.3.1 Chronic Pancreatitis
    1.3.2 Acute Pancreatitis
    1.3.3 Hereditary Pancreatitis
    1.4 Tobacco Smoking
    1.5 Alcohol Consumption
    1.6 Body Mass Index and Obesity
    1.7 Diabetes Mellitus
    1.8 Dietary Patterns 1.9 Poor Oral Hygiene
    1.10 ABO Blood Group
    1.11 Potential Risk Factors
    1.12 Study Design and Ongoing Epidemiological Projects
    1.13 Conclusions
    References
    Chapter 2: Epidemiology of Pancreatic Cancer
    2.1 Introduction
    2.2 Worldwide Incidence
    2.3 Trends in Incidence
    2.3.1 Data from The Netherlands
    2.3.2 Data from Austria
    2.3.3 Data from Canada
    2.3.4 Data from Puerto Rico
    2.3.5 Data from the USA
    2.4 Worldwide Mortality
    2.4.1 Data from The Netherlands
    2.4.2 Data from Austria
    2.4.3 Data from Canada
    2.4.4 Data from Puerto Rico 2.4.5 Data from the USA
    2.5 Conclusion
    References
    Chapter 3: Hereditary Syndromes and Pancreatic Cancer
    3.1 Introduction
    3.2 Hereditary Tumour Predisposition Syndromes
    3.2.1 Peutz-Jeghers Syndrome
    3.2.2 Familial Atypical Multiple Mole Melanoma and Pancreatic Cancer Syndrome (FAMMM)
    3.2.3 Hereditary Breast and Ovarian Cancer Syndrome
    3.2.4 PALB2 Gene Mutations
    3.2.5 ATM Gene Mutations
    3.2.6 Lynch Syndrome
    3.3 Hereditary Pancreatitis
    3.4 Other Tumour Predisposition Syndromes
    3.4.1 Li Fraumeni Syndrome
    3.4.2 Familial Adenomatous Polyposis 3.4.3 Germline Mutations in Other Cancer Genes
    3.5 Testing and Tools
    3.6 Surveillance/Screening Recommendations
    3.7 Conclusion
    References
    Chapter 4: Familial Pancreatic Cancer
    4.1 Introduction
    4.2 Familial Pancreatic Cancer
    4.3 Pancreatic Cancer Susceptibility Genes in Patients with Familial Pancreatic Cancer
    4.3.1 ATM
    4.3.2 BRCA1, BRCA2, PALB2
    4.3.3 CDKN2A
    4.3.4 Hereditary Pancreatitis Genes
    4.3.5 Other Inherited Syndromes
    4.4 Pancreatic Cancer Susceptibility Genes in Patients with Sporadic PDAC 4.5 Pancreatic Cancer Susceptibility Genes in Patients with Pancreatic Cancer Precursor Lesions
    4.6 Screening for Patients with Pathogenic Germline Variants
    4.7 Conclusion
    References
    Part II: Education, Training and Quality of Care
    Chapter 5: Education and Training in Pancreatic Surgery
    5.1 Structure of Training Pathways
    5.1.1 North-American Training Programmes
    5.1.2 European Training Programmes
    5.1.3 Australasian Programmes
    5.1.4 Effect of Training Programmes on Clinical Outcomes
    5.1.5 Workforce Prediction
    5.2 Standards of Training
    5.2.1 Period of Training
    Digital Access Springer 2021