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  • Book
    Bryan J. Wells, Pablo A. Quintero, Geoffrey Southmayd, editors.
    Summary: This book serves as a pocket-sized resource to aid with the diagnosis and management of cardiovascular disease in the inpatient setting. Containing up-to-date information from guidelines and clinical trials, this book is the only handbook-style reference on cardiac care designed specifically for the hospitalist. The first section of the book covers cardiac pathology with an emphasis on evidence-based and guideline-based approaches to patient care. Each chapter focuses on a specific cardiovascular disease state such as acute coronary syndrome, atrial fibrillation, pulmonary hypertension, and aortic disease. The second section examines the differential diagnoses and recommended workup for common cardiac chief complaints including chest pain, palpitations, syncope, and dyspnea. The third and final section discusses indications and interpretation of commonly used cardiac procedures and imaging modalities. This book provides a concise review over a broad range of cardiovascular disease states in an accessible handbook-style to aid with the care of these patients. The Handbook of Inpatient Cardiology is an essential resource for physician hospitalists caring for cardiac patients on the medical ward in addition to cardiology physicians and trainees, affiliate providers, and students.

    Contents:
    Intro
    Contents
    Contributors
    Abbreviations
    Introduction
    Part I: Cardiac Pathology
    Chapter 1: Acute Coronary Syndrome
    Definitions (Table 1.1)
    Pathophysiology
    Prognosis
    Classification
    Initial Management (Fig. 1.3)
    Risk Stratification
    Conservative/Ischemia-Guided Strategy
    Early Invasive Management Strategy
    Post-ACS Management
    References
    Chapter 2: Stable Ischemic Heart Disease
    Diagnosis
    Differentiating CAD, SIHD, and ACS
    Cardiovascular Risk in Patients Presenting with Chest Pain (Fig. 2.1)
    Physical Exam Preliminary Workup of Suspected SIHD
    Specific Testing in Suspected CAD: Who to Test
    Specific Testing in Suspected CAD: Stress Testing (See Table 2.2)
    Specific Testing in Suspected CAD: Anatomical Testing
    Specific Testing in Suspected CAD: Invasive Coronary Angiography
    Specific Testing in Already Known CAD
    SIHD Without Obstructive CAD
    When to Refer to a Cardiologist
    Guideline-Directed Medical Treatment (GDMT)
    Goals of Treatment
    Behavior Modification
    Pharmacologic Therapy for Specific Risk Factors
    Lipids
    Hypertension
    Diabetes
    Obesity Pharmacologic Therapy to Prevent MI or Death in SIHD Independent of Risk Factors
    Antiplatelet Therapy
    Anticoagulation
    Other Therapies
    Medications that Treat Angina
    Revascularization in SIHD
    References
    Chapter 3: Atrial Fibrillation and Atrial Flutter
    Terminology
    Epidemiology of Atrial Fibrillation
    Consequences of Atrial Fibrillation
    Thromboembolic Risk
    Evaluation of Patients with New Atrial Fibrillation
    Anticoagulation for Atrial Fibrillation
    Heart Rate Control in Atrial Fibrillation
    Rhythm Control in Atrial Fibrillation
    Antiarrhythmic Therapy Atrial Flutter
    When Should a Cardiology Consultation Be Considered
    References
    Chapter 4: Supraventricular Tachycardia
    Supraventricular Tachycardia
    Definition, Incidence and Prevalence
    Interventions for SVT
    Vagal Maneuvers
    Adenosine
    Electrical Cardioversion
    Approach to the Patient with SVT
    12-Lead Electrocardiogram (ECG)
    Response to Adenosine
    AV Nodal Reentrant Tachycardia
    Typical AVNRT
    Atypical AVNRT
    AV Reentrant Tachycardia
    Pre-Excited Atrial Fibrillation
    Orthodromic AVRT
    Antidromic AVRT
    Atrial Tachycardia
    Focal Atrial Tachycardia Multifocal Atrial Tachycardia
    Junctional Tachycardia
    References
    Chapter 5: Ventricular Arrhythmias
    Terminology and Definitions
    Epidemiology
    Mechanisms of Ventricular Ectopy and Tachycardia
    Diagnosis of Ventricular Tachycardia
    The Surface ECG
    Inpatient Management of Ventricular Tachycardia
    References
    Chapter 6: Bradyarrhythmias and AV Block
    Sinus Bradycardia
    Definition
    Causes
    Clinical Presentation
    Diagnosis/ECG Features
    Treatment
    Sinus Pauses or Arrest
    Sinoatrial Exit Block
    Sinus Node Dysfunction (SND)
    Definition
    Digital Access Springer 2020
  • Article
    Simões-Mendes B, Madeira-Lopes A, van Uden N.
    Z Allg Mikrobiol. 1978;18(4):275-9.
    Mass formation of petite mutants took place in a strain of Saccharomyces cerevisiae when grown at superoptimal temperatures. After an initial period of exponential growth, a second period followed during which exponential death and net exponential petite mutation concurred with exponential growth. The specific rates of the three exponential processes were of the same order of magnitude and varied with the temperature. Net exponential petite mutation did not occur during the deathless first period of growth at superoptimal temperatures nor at any time during growth at suboptimal temperatures. Mitochondria are discussed as possible targets of thermal death in mesophilic yeasts.
    Digital Access Access Options