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  • Book
    edited by Patrick McGorry, Ian Hickie.
    Summary: Psychiatric diagnosis is experiencing a crisis of confidence. Current approaches are outmoded, with reform desperately needed. Clinical staging is a solution to this crisis. Clinical staging addresses the limitations of current diagnostic systems by recognising the full continuum or trajectory of mental illness from asymptomatic to chronic illness. It acknowledges the overlap between mental health symptoms during early stages and directly links each stage to treatment and underlying cognitive, neurological and biological changes. This approach enhances chances of early identification, promotes the implementation of safer treatments, and increases opportunities to alter the negative trajectory of mental disorders. This book comprehensively describes the conceptual basis of clinical staging in psychiatry, details current progress in identifying biomarkers for each stage, and explores the implications of staging on treatment and health systems. This book provides a foundation for transformational reform in psychiatric diagnosis.

    Contents:
    Diagnosis without borders : a pluripotential approach to preventive intervention in emerging mental disorders / Patrick D. McGorry
    Clinical staging and its potential to enhance mental health care / Cristina Mei, Patrick D. McGorry, Ian B. Hickie
    Time for a change : a more dynamic perspective on psychopathology / Johanna T.W. Wigman, Stijn de Vos
    A moving target : how risk for mental disorder can be modelled in dynamic rather than static term / Barnaby Nelson, Patrick D. McGorry, Jessica A. Hartmann
    The utility of clinical staging in youth mental health settings : neurobiological and longitudinal data from sydney-based studies of transdiagnostic cohorts / Ian B. Hickie, Joanne S. Carpenter, Frank Iorfino, Elizabeth Scott, Shane Cross, Daniel F. Hermens
    Neuroimaging and staging : do disparate mental illnesses have distinct neurobiological trajectories? / Cali F. Bartholomeusz, Christos Pantelis
    Staging of cognition in psychiatric illness / Kelly Allott
    Neuroinflammation and staging / Bernhard T. Baune
    Bioactive and inflammatory markers in emerging psychotic disorders / Gregor E. Berger
    Electroencephalography and staging / Suzie Lavoie
    Novel treatment strategies : biological / Paul Amminger, Maximus Berger
    Psychosocial interventions for youth mental health / Eoin Killackey, Mario Alvarez-Jimenez
    Transforming cultures to enable stage-related care of mental ill health : a youth mental health challenge / Patrick D. McGorry, Ian B. Hickie, Shane Cross
    The quest for clinical utility and construct validity in psychiatric diagnosis / Patrick D. McGorry.
    Digital Access Cambridge 2019