BookSijo J. Parekattil, Sandro C. Esteves, Ashok Agarwal, editors.
Summary: A groundbreaking contribution to the literature now in its revised and expanded second edition, this textbook offers a comprehensive review of diagnostic and treatment techniques for male infertility. This state-of-the-art, evidence-based textbook incorporates new multidisciplinary and complementary medicine approaches to create a first-of-its-kind guide to treatment strategies for male infertility and beyond. While this new edition is primarily designed as a reference for students and residents in reproductive medicine and andrology, it will be equally useful as well for professionals in urology, reproductive endocrinology, embryology, and research fields who are interested in the role that antioxidants play in male infertility. World-renowned experts in these areas have been selected to participate in this work. Careful selection of the highest quality content will span the whole range of topics in the area of male infertility, providing a complete review of well-established and current diagnostic and treatment techniques for male infertility. The incorporation of 20 new chapters will enhance the books appeal by including the most recent advances brought to the male infertility arena. Additionally, this edition incorporates new features, including bulleted key points, review criteria and select video clips demonstrating some of the most fascinating male infertility treatment modalities. A dedicated new section on current guidelines on male infertility will enlighten readers on how to most optimally manage male infertility clinical scenarios. Covering all aspects of diagnosis and management, ART, lifestyle factors and associated conditions for male infertility, Male Infertility: Contemporary Clinical Approaches, Andrology, ART and Antioxidants will be a readily accessible, high quality reference for medical students and residents, and will be of significant value to professionals working in the various fields treating this condition as well.
Contents:
Intro
Foreword
Preface
About the Editors
Contents
Contributors
Part I: Male Infertility Diagnosis and Management
1: Causes of Male Infertility
1.1 Introduction
1.2 Causes of Male Infertility
1.2.1 Pre-testicular
1.2.1.1 Hypogonadotropic Hypogonadism
1.2.1.2 Elevated Prolactin
1.2.1.3 Pharmacologic
1.2.1.4 Idiopathic Hypogonadotropic Hypogonadism and Kallmann Syndrome
1.2.1.5 Testicular
Varicocele
Cryptorchidism
Testicular Cancer
1.2.1.6 Ionizing Radiation
1.2.1.7 Chemotherapy
1.2.1.8 Genetic Azoospermia/Oligospermia 1.2.1.9 Lifestyle Factors
1.2.1.10 Testicular Injury
1.2.1.11 Primary Ciliary Dyskinesia
1.2.1.12 Antisperm Antibodies
1.2.2 Post-testicular
1.2.2.1 Absence of the Vas Deferens
1.2.2.2 Young's Syndrome
1.2.2.3 EjDO/Seminal Vesicle Dysfunction
1.2.2.4 Nerve Injury
1.2.2.5 Medications
1.2.2.6 Coital
1.3 Conclusion
1.4 Review Criteria
References
Notable Suggested Readings from the Last 5 Years
2: Epidemiologic Considerations in Male Infertility
2.1 Introduction
2.2 Epidemiology of Infertility 2.2.1 Incidence and Prevalence of Infertility in Developed Countries
2.2.2 Infertility in the Developing World
2.2.3 Reproduction-a Matter of Chance: The Natural History of Infertility
2.3 Diagnostic Accuracy and Utility of Semen Studies
2.3.1 Relationship Between Semen Parameters and Male Infertility
2.3.2 Do Semen Parameters Prospectively Predict Fertility and Assisted Reproductive Technique Outcomes?
2.3.3 Novel Assays for Diagnosis of Male Infertility
2.4 Are Sperm Counts Declining?
2.5 Health-Care Resource Utilization for Male Infertility 2.5.1 Office Visits and Ambulatory Surgery Cases
2.5.2 Assisted Reproductive Technology
2.5.3 Cost of Treatment for Male Infertility
2.6 Cost Analysis Models for Management of Male Infertility
2.7 Conclusion
2.8 Review Criteria
References
3: Laboratory Evidence for Male Infertility
3.1 Introduction
3.2 WHO Guidelines for Assessment of Semen Specimen
3.3 Laboratory Evaluation of Male Factor Infertility
3.3.1 Basic Semen Analysis
3.3.1.1 Collection
3.3.1.2 Volume
3.3.1.3 Liquefaction and Viscosity
3.3.1.4 pH [normal > 7.2] 3.3.1.5 Concentration
3.3.1.6 Motility
3.3.1.7 Morphology
3.3.1.8 Agglutination
3.3.1.9 Leukocytospermia
3.4 Retrograde or Post-Ejaculatory Urinalysis (PEUA)
3.5 Reactive Oxygen Species (ROS) Testing
3.6 Acrosome Reaction Testing
3.7 Antisperm Antibody (ASA) Testing
3.8 Sperm Viability Testing
3.9 Advanced Semen Testing
3.9.1 Sperm DNA Fragmentation (SDF)
3.9.2 Sperm Chromatin Structure Assay (SCSA)
3.9.3 Terminal Deoxynucleotidyl Transferase dUTP Nick End Labeling (TUNEL)
3.9.4 Single-Cell Gel Electrophoresis Assay (Comet)