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  • Book
    Jonathan M. Meyer, Stephen M. Stahl ; with illustrations by Nancy Muntner.
    Digital : Cambridge2020
    Initiating clozapine -- Understanding hematologic monitoring and benign ethnic neutropenia -- Binding profile, metabolism, kinetics, drug interactions and use of plasma levels -- Managing constipation -- Managing sialorrhea -- Managing sedation, orthostasis and tachycardia -- Managing metabolic adverse effects -- Managing seizure risk and stuttering -- Fever, myocarditis, interstitial nephritis, DRESS, serositis and cardiomyopathy -- Eosinophilia, leukocytosis, thrombocytopenia, thrombocytosis, anemia, hepatic -- Function abnormalities -- Managing enuresis and incontinence, priapism, venous thromboembolism -- Neuroleptic malignant syndrome, tardive dyskinesia and obsessive compulsive disorder -- The efficacy story: treatment resistant schizophrenia, psychogenic polydipsia -- Treatment intolerant schizophrenia, suicidality, violence, mania and parkinson's disease psychosis -- Addressing clozapine positive symptom nonresponse in schizophrenia spectrum -- Patients -- Discontinuing clozapine and management of cholinergic rebound -- Special topics: child and adolescent patients, elderly patients, patients with -- Intellectual disability, pregnancy and risk for major congenital malformation, lactation, overdose, postmortem redistribution.