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  • Book
    Jonathan M. Meyer, Stephen M. Stahl ; with illustrations by Nancy Muntner.
    Contents:
    Initiating clozapine
    Understanding hematologic monitoring and benign ethnic neutropenia
    Binding profile, metabolism, kinetics, drug interactions and use of plasma levels
    Managing constipation
    Managing sialorrhea
    Managing sedation, orthostasis and tachycardia
    Managing metabolic adverse effects
    Managing seizure risk and stuttering
    Fever, myocarditis, interstitial nephritis, DRESS, serositis and cardiomyopathy
    Eosinophilia, leukocytosis, thrombocytopenia, thrombocytosis, anemia, hepatic
    Function abnormalities
    Managing enuresis and incontinence, priapism, venous thromboembolism
    Neuroleptic malignant syndrome, tardive dyskinesia and obsessive compulsive disorder
    The efficacy story: treatment resistant schizophrenia, psychogenic polydipsia
    Treatment intolerant schizophrenia, suicidality, violence, mania and parkinson's disease psychosis
    Addressing clozapine positive symptom nonresponse in schizophrenia spectrum
    Patients
    Discontinuing clozapine and management of cholinergic rebound
    Special topics: child and adolescent patients, elderly patients, patients with
    Intellectual disability, pregnancy and risk for major congenital malformation, lactation, overdose, postmortem redistribution.
    Digital Access Cambridge 2020