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  • Book
    [edited by] Piero Nicolai, Marco Ferrari, Roberto Maroldi, Marco Maria Fontanella, Lena Hirtler, Manfred Tschabitscher, Luigi Fabrizio Rodella.
    Summary: "Highlighting the most recent experience from seven top leaders and innovators in the field, this seminal new work presents detailed topographic anatomy of the skull base and adjacent areas in a way not previously seen before. The result is a multidisciplinary atlas merging anatomy, otolaryngology, neurosurgery, and radiology, so as to facilitate creation of a mental "virtual reconstruction" of the complete approach and operative situs. The result is a greatly extended range of surgical possibilities into previously uncharted territory using endoscopic technology. Key Features: Provides the basis for cultivating a firm and confident understanding of the 3D anatomy of this intricately complex region Emphasizes the ability of the endoscopic surgeon to integrate CT and MRI findings into the surgical planning process A logical and modular organization of the contents intends to make for easy correlation with the surgical literature Brilliant step-by-step presentation of dissections using cadavers, helping readers to fully understand all the anatomical nuances Numerous previously unpublished approaches covered here for the first time in a book, step by step Endoscopic Transnasal Anatomy of the Skull Base and Adjacent Areas is an indispensable resource for fellows and specialists in neurosurgery and ENT surgery wishing to widen their competence in endoscopic skull base surgery"-- Provided by publisher.
    Digital Access
    Provider
    Version
    Thieme MedOne Neurosurgery
    2019
    Thieme MedOne Otolaryngology
    2020
    Thieme-Connect
    2020
  • Article
    Rottem S, Markowitz O, Razin S.
    Eur J Biochem. 1978 Apr 17;85(2):451-6.
    Inhibition of Proteus mirabilis growth by cerulenin, a specific inhibitor of fatty acid biosynthesis, was reversed by exogenously supplied fatty acid mixtures containing oleic acid and palmitic or pentadecanoic acids. The growth rate of the cells treated with cerulenin in the presence of the fatty acid mixtures was slower, however, than that of untreated cells, and their lipopolysaccharide content was decreased by 30-50%, resulting in an increased sensitivity of the organisms to rifamycin and vancomycin. Polyacrylamide gel electrophoresis of the lipopolysaccharide fraction from cerulenin-treated cells revealed that of the two P. mirabilis lipopolysaccharide types, the relative amount of the higher molecular weight lipopolysaccharide was reduced from 50% to 30% of the total lipopolysaccharide. Fatty acid analysis of the phospholipid and lipopolysaccharide fractions from cells grown with cerulenin, pentadecanoate, and oleate revealed that over 60% of the native even-numbered fatty acids of the phospholipid fraction was substituted by the odd-numbered fatty acid, while no incorporation of either the pentadecanoate or oleate could be demonstrated in the lipid A moiety of the lipopolysaccharide. The only change in the lipid A observed was an increase in the content of 3-hydroxymyristic acid accompanied by a decrease in the nonhydroxylated fatty acids, supporting the highly conserved nature of this molecule.
    Digital Access Access Options