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  • Book
    [edited by] Michelle A. Clark, Richard Finkel, Jose A. Rey, Karen Whalen ; series editor Richard A. Harvey.
    Summary: The Fifth Edition enables rapid review and assimilation of complex information and focuses on the essentials of medical pharmacology. Clear, sequential pictures present mechanisms of action and actually show rather than tell students how drugs work. This book features a signature outline format with more than 500 full-color illustrations and cross-references to other volumes in this bestselling, student-oriented series.

    Contents:
    Introduction to pharmacology
    Drugs affecting the autonomic nervous system
    Drugs affecting the central nervous system
    Drugs affecting the cardiovascular system
    Drugs affecting the endocrine system
    Drugs affecting other systems
    Chemotherapeutic drugs
    Anti-inflammatory drugs and autacoids.
  • Article
    Väisänen E, Naarala M, Kontiainen H, Meriläinen V, Heikkilä L, Malinen L.
    Acta Psychiatr Scand. 1978 Mar;57(3):193-201.
    Maprotiline (Ludiomil) and doxepin were compared in the treatment of depression in a double-blind multicentre trial. Four centres and 95 in- and out-patients took part in the trial. The severity of depression was evaluated with the aid of a visual analogue scale and nine target symptoms. Both maprotiline and doxepin diminished neurotic as well as psychotic depression significantly. The mean time of onset of action was 7.0 days in the maprotiline group and 7.7 days in the doxepin group. No statistically significant differences in antidepressive effect were found between the treatments. Two patients in the maprotiline group and four patients in the doxepin group discontinued the treatment because of unwanted effects, one patient in each group because of lack of efficacy and nine patients due to reasons not related to the treatment.
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