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  • Book
    Claudia Krebs, Joanne Weinberg, Elizabeth Akesson, Esma Dilli.
    Contents:
    Introduction to the nervous system and basic neurophysiology
    Overview of the central nervous system
    Overview of the peripheral nervous system
    Overview of the visceral nervous system
    The spinal cord
    Overview and organization of the brainstem
    Ascending sensory tracts
    Descending motor tracts
    Control of eye movements
    Sensory and motor innervation of the head and neck
    Hearing and balance
    Brainstem systems and review
    The cerebral cortex
    The thalamus
    The visual system
    The basal ganglia
    The cerebellum
    The integration of motor control.
  • Article
    Pöldinger W.
    Acta Psychiatr Belg. 1978 Jan-Feb;78(1):96-101.
    A total of sixty patients were trated with bromperidol first in open conditions (20 patients), then on a double blind basis (40 patients) with haloperidol as the reference substance. The open study lasted for four weeks; the drug was administrated in the form of 1 mg tablets. The daily dose (initial dose: 1 mg; mean dose at the end of the trial: 4.47 mg) was always administered in one single dose. Nineteen patients finished the trial, and in 18 cases the therapeutic result was considered very good to good. These results were confirmed by statistical analysis. Nine patients exhibited mild to moderate extrapyramidal concomitant symptoms; no other side effects were observed. The results of detailed laboratory tests and evaluations of various quantitative and qualitative tolerability parameters were not indicative of toxic effects. In the double blind study with haloperidol, both substances were found to be highly effective in the treatment of psychotic syndromes belonging predominantly to the schizophrenia group. Certain clues, including the onset of action, seem to be indicative of the superiority of bromperidol. No differences were observed with respect to side effects and general tolerability.
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