Bookeditor, Gerhard Seifer ; contributors, M. Altmannsberger and others.
Summary: New methods in immunocytochemistry and hybridization techniques enable the pathologist active in diagnosis to clarify more effectively problems in the classification and prognosis of tumors. By adopting these methods into his diagnostic repertoire it will be possible to create a closer, more productive connection between morphological diagnosis and clinical work. This volume gives the reader an up-to-date general survey from international experts of the method, technique and practical application of these new procedures.
Contents:
Monoclonal Antibodies to Human Tumor Antigens
Biochemical Markers for Human Cancer
Immunohistochemical Methods for the Demonstration of Tumor Markers
Epithelial Tumor Markers: Cytokeratins and Tissue Polypeptide Antigen (TPA)
Epithelial Tumor Markers: Oncofetal Antigens (Carcinoembryonic Antigen, Alpha Fetoprotein) and Epithelial Membrane Antigen
Epithelial Tumor Markers: Special Markers of Glandular Differentiation
Mesenchymal Tumor Markers: Intermediate Filaments
Mesenchymal Tumor Markers: Special Proteins and Enzymes
Proteoglycans and the Intercellular Tumor Matrix
Basal Membrane Antigens as Tumor Markers
Lectins and Blood Group Substances as "Tumor Markers"
Neuroendocrine Tumor Markers
Morphological Markers in Neuro-Oncology
Viral Tumor Markers
Cell, Tissue and Organ Specific Tumor Markers: An Overview
Subject Index.