BookMichael Lieberman, PhD, Distinguished Teaching Professor, Department of Molecular Genetics,
... Show More Biochemistry and Microbiology, University of Cincinnati College of Medicine, Cincinnati, Ohio, Alisa Peet, MD, Associate Dean Clinical Education, Associate Professor of Clinical Medicine, Lewis Katz School of Medicine at Temple University, Philadelphia, Pennsylvania ; illustrations by Matthew Chansky.
Contents:
I: Fuel metabolism
Metabolic fuels and dietary components
The fed or absorptive state
Fasting
II: Chemical and biologic foundations of biochemistry
Water, acids, bases, and buffers
Structures of the major compounds of the body
Amino acids in proteins
Structure–function relationships in proteins
Enzymes as catalysts
Regulation of enzymes
Relationship between cell biology and biochemistry
Cell signaling by chemical messengers
III: Gene expression and the synthesis of proteins
Structure of the nucleic acids
Synthesis of DNA
Transcription: synthesis of RNA
Translation: synthesis of proteins
Regulation of gene expression
Use of recombinant DNA techniques in medicine
The molecular biology of cancer
IV: Carbohydrate metabolism, fuel oxidation, and the generation of adenosine triphosphate
Basic concepts in the regulation of fuel metabolism by insulin, glucagon, and other hormones
Cellular bioenergetics: adenosine triphosphate and O2
Digestion, absorption, and transport of carbohydrates
Generation of adenosine triphosphate from glucose, fructose, and galactose: glycolysis
Tricarboxylic acid cycle
Oxidative phosphorylation and mitochondrial function
Oxygen toxicity and free-radical injury
Formation and degradation of glycogen
Pentose phosphate pathway and the synthesis of glycosides, lactose, glycoproteins, and glycolipids
Gluconeogenesis and maintenance of blood glucose levels
V: Lipid metabolism
Digestion and transport of dietary lipids
Oxidation of fatty acids and ketone bodies
Synthesis of fatty acids, triacylglycerols, and the major membrane lipids
Cholesterol absorption, synthesis, metabolism, and fate
Metabolism of ethanol
Integration of carbohydrate and lipid metabolism
VI: Nitrogen metabolism
Protein digestion and amino acid absorption
Fate of amino acid nitrogen: urea cycle
Synthesis and degradation of amino acids
Tetrahydrofolate, vitamin B12, and S-adenosylmethionine
Purine and pyrimidine metabolism
Intertissue relationships in the metabolism of amino acids VII: tissue metabolism
Actions of hormones that regulate fuel metabolism
The biochemistry of erythrocytes and other blood cells
Blood plasma proteins, coagulation, and fibrinolysis
Liver metabolism
Metabolism of muscle at rest and during exercise
Metabolism of the nervous system
The extracellular matrix and connective tissue.
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Books: General Collection (Downstairs)
QP514.2 .L54 2018
1