BookJoo Chuan Tong and Shoba Ranganathan.
Summary: Computational pre-screening of antigens is now routinely applied to the discovery of vaccine candidates. Computer-aided vaccine design is a comprehensive introduction to this exciting field of study. The book is intended to be a textbook for researchers and for courses in bioinformatics, as well as a laboratory reference guide. It is written mainly for biologists who want to understand the current methods of computer-aided vaccine design. The contents are designed to help biologists appreciate the underlying concepts and algorithms used, as well as limitations of the methods and strategies for their use.
Contents:
1. MHC and T cell responses
2. Immunoglobulins and B cell responses
3. Scientific publications and databases
4. Database design; Computational T cell vaccine design
5. Computational T cell vaccine design
6. Computational B cell vaccine design
7. infectious disease informatics
8. Vaccine safety and quality assessments
9. Vaccine adjuvant informatics
Index.