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  • Book
    Connie M. Rhee, Kamyar Kalantar-Zadeh, Gregory A. Brent, editors.
    Summary: This comprehensive book examines the complex interplay between endocrine and kidney disorders, and how this inter-relationship impacts patients with chronic kidney disease. Authored by experts in areas of endocrinology and nephrology, chapters cover a variety of topics, including diabetes, metabolic syndrome, thyroid dysfunction, gonadal disorders, dyslipidemia, mineral bone disorders, obesity, and pituitary disorders. These comorbidities are thoroughly examined and provide the clinician, researcher, and trainee with a greater understanding of the impact of endocrine disorders on kidney disease patients, the ability to identify persistent gaps in knowledge for future investigation, and move closer towards the goal of improving the health and survival of the chronic kidney disease population. .

    Contents:
    Intro; Preface; Contents; Contributors; Part I: Diabetes, Insulin Resistance, and the Metabolic Syndrome;
    1: Insulin Resistance and the Metabolic Syndrome in Kidney Disease (e.g., the Cardiorenal Metabolic Syndrome); Introduction; Definition(s) of the Cardiorenal Metabolic Syndrome; Epidemiology of the Cardiorenal Metabolic Syndrome; The Cardiorenal Metabolic Syndrome and CKD; Insulin Resistance/Hyperinsulinemia; Inflammatory Cytokines; Inappropriate Activation of the RAAS; Endothelial Dysfunction; Conclusions and Perspectives; References;
    2: Diabetic Kidney Disease; Epidemiology PathophysiologyNatural History; Diagnosis; Prevention and Treatment; Complications of Chronic Kidney Disease; Conclusions; References;
    3: Glucose Homeostasis and the Burnt-Out Diabetes Phenomenon in Patients with Kidney Disease; Introduction; Glucose Homeostasis in Kidney Disease; Clearance of Insulin; Hypoglycemia Due to Antidiabetic and Other Agents; Decreased Gluconeogenesis in the Kidney; Insulin Secretion and Insulin Resistance; Protein-Energy Wasting (PEW); Burnt-Out Diabetes Phenomenon; Hemodialysis-Related Hypoglycemia and Hyperglycemia; Hemodialysis-Induced Hypoglycemia Metabolic Effects Associated with Glucose-Free DialysateHemodialysis-Associated Hyperglycemia; Insulin Removal by Hemodialysis; Hemodialysis-Associated Hyperglycemia Resembling the Somogyi Effect; References;
    4: Glycemic Metrics and Targets in Kidney Disease; Introduction; Glycemic Metrics and Their Role in Kidney Disease; Glycated Hemoglobin (A1C); Glycated Albumin (GA); Fructosamine; 1,5-Anhydroglucitol (1,5-AG); Continuous Glucose Monitoring (CGM); Glycemic Targets in Kidney Disease; Conclusion; References;
    5: Diabetic Pharmacotherapies in Kidney Disease; Introduction; Biguanides SulfonylureasMeglitinides; Glucagon-Like Peptide 1 Receptor Agonists (GLP-1 RAs); Dipeptidyl Peptidase IV (DPP-4) Inhibitors; Thiazolidinediones; Sodium-Glucose Co-transporter 2 (SGLT2) Inhibitors; Alpha-Glucosidase Inhibitors; Bromocriptine; Bile Acid Resins; Insulin; Amylin Analog; Impact of Antihyperglycemic Agents on Renal Function; Conclusion; References;
    6: Diabetes Mellitus and Renal Transplantation; Introduction; Changes in Glucose Homeostasis During Peri-Kidney Transplantation; Changes in Glucose Homeostasis During the Immediate Posttransplant Period New-Onset Diabetes After Kidney TransplantationClinical and Economic Significance of NODAT; It Is Important to Decrease the Incidence of NODAT; Timing of NODAT; Pathogenesis of NODAT; Can Lifestyle Modification Be Adapted for Prevention of NODAT?; Drugs for Preventing NODAT; Conclusion; References; Part II: Thyroid Dysfunction;
    7: Evaluating Thyroid Function Tests in Patients with Kidney Disease; Introduction; TSH Measurement; TSH Levels in Chronic Kidney Disease Patients; Measuring Free Thyroxine and Free Triiodothyronine; Thyroxine (T4) Changes with CKD
    Digital Access Springer 2019