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  • Book
    Christine N. Duncan, Julie-An M. Talano, Jennifer A. McArthur, editors.
    Summary: This volume provides a comprehensive overview of critical care of the pediatric immunocompromised hematology-oncology patient. The text focuses on unique aspects of the pediatric immunocompromised patient that predisposes the child to significant illness, and presents critical care management strategies specific to the patient population. In addition to chapters on oncology, primary immune deficiency, immunocompromised hematology, and hematopoietic cell transplant patients, the book covers the changing landscape of ICU care, pharmacologic considerations, and psychological and social aspects of the critical care of hematology-oncology patients. Written by experts from a range of disciplines, Critical Care of the Pediatric Immunocompromised Hematology/Oncology Patient: An Evidence-Based Guide is a valuable resource for clinicians and practitioners who treat this patient population.

    Contents:
    Intro; Contents; Contributors; Part I: Predisposing Diseases and Specific Considerations in Critical Illness;
    Chapter 1: The Changing Landscape of the Critical Care of Pediatric Immunocompromised Hematology and Oncology Patients; References;
    Chapter 2: Diagnosis and Treatment-Related Complications of Acute Leukemia; Introduction; Tumor Lysis Syndrome; TLS Classification and Grading; TLS Management; Hyperuricemia; Hyperkalemia; Hyperphosphatemia; Hypocalcemia; Indications for Dialysis; Hyperleukocytosis and Leukostasis; Mediastinal Masses and Superior Vena Cava Syndrome; CNS Emergencies ThrombosisTyphlitis; Pancreatitis; Acute Promyelocytic Leukemia and Differentiation Syndrome; Conclusion; References;
    Chapter 3: Neuro-oncologic Emergencies; Introduction; Increased Intracranial Pressure/Hydrocephalus/Herniation; Seizures/Status Epilepticus; Spinal Cord Compression; Encephalopathy with Chemotherapy; Endocrinopathies; Radiation Injury and Radiation Necrosis; CNS Infection; Conclusions; References;
    Chapter 4: Solid Tumors Outside of the Central Nervous System; Anterior Mediastinal Masses; Airway and Cardiovascular Compromise; Neuroblastoma; Immunotherapy for Neuroblastoma Spinal Cord CompressionSurgery and Surgical Complications; Metastatic Osteosarcoma; Surgical Approach; Desmoplastic Round Blue Cell Tumor; Enhanced Recovery After Surgery; Preoperative; Intraoperative; Postoperative; References;
    Chapter 5: Primary Immunodeficiency Diseases; Introduction; Normal Immune System; Innate Immunity; Adaptive Immunity; Primary Immunodeficiency Diseases; Classification; Clinical Manifestations; Diagnosis; Complications; Management; Conclusions; References;
    Chapter 6: Care of the Critically Ill Pediatric Sickle Cell Patient; Introduction and Chapter Overview Cardiovascular ConcernsBaseline Cardiovascular Pathology in SCD; Cardiomegaly and Left Ventricular Dysfunction; Cardiac Consequences of Iron Overload; ICU Concerns; Diastolic Dysfunction; Pulmonary Hypertension; Myocardial Ischemia; Hepatic and Biliary Concerns; Hepatobiliary Clinical Syndromes Secondary to Sickling; Acute Sickle Hepatic Crisis; Intrahepatic Cholestasis; Hepatic Sequestration Crisis; Hepatobiliary Dysfunction Secondary to Coexisting Conditions; Hepatic Consequences of Iron Overload; Viral Hepatitis; Acute Cholecystitis; Pyogenic Liver Abscess; Autoimmune Hepatitis Focal Nodular HyperplasiaHemodynamic Concerns; Thromboembolism in Sickle Cell Disease; Risk Factors Secondary to Sickling; Risk Factors Secondary to Traditional Causes; Splenic Concerns; Splenic Sequestration Crisis; Sepsis; Musculoskeletal Concerns; Fat Embolism Syndrome; Neurological Concerns; Initial Management of Possible Stroke; Diagnosis; Ischemic Stroke; Hemorrhagic Stroke; Ischemic Transformation; Subarachnoid Hemorrhage; Intraventricular Hemorrhage; Renal Concerns; Baseline Renal Pathology in SCD; Acute Kidney Injury; Prerenal AKI; Intrinsic AKI; Postrenal AKI; Pulmonary Concerns
    Digital Access Springer 2019