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  • Book
    Keith C. Meyer, Steven D. Nathan, editors.
    Intro; Preface; Contents; Contributors; Chapter 1: Classification and Nomenclature of Interstitial Lung Disease; Introduction; Current Approaches to the Classification of ILD; Idiopathic Interstitial Pneumonias; Differentiating IPF from Non-IPF ILD; Summary; References; Chapter 2: Idiopathic Pulmonary Fibrosis: The Epidemiology and Natural History of Disease; Introduction; The Epidemiology of IPF; Background; Prevalence, Incidence, and Secular Trends; Mortality Rates and Secular Trends; Risk Factors; Definitions and Limitations; Genetic Risk Factors; Cigarette Smoking; Occupational Exposures Metal DustsWood Dust; Agriculture (Farming and Livestock); Sand, Stone, and Silica; Miscellaneous Exposures; The Natural History of IPF; Background; Predicting Survival; Rate of Decline in FVC; The Underlying Cause of Death; Phenotypic Subgroups; Long-Term Survivors; Rapid Progression from Diagnosis; Stable Disease Followed by Accelerated Disease; Acute Exacerbations of IPF; Subclinical Disease; Specific Clinical Phenotypes of Disease; IPF with Pulmonary Hypertension; Combined Pulmonary Fibrosis and Emphysema; Summary; References; Chapter 3: Histopathology of IPF and Related Disorders IntroductionHistopathologic Classification of Idiopathic Interstitial Pneumonias; Usual Interstitial Pneumonia; Clinical Features; Pathologic Features; Desquamative Interstitial Pneumonia/Respiratory Bronchiolitis Interstitial Lung Disease; Clinical Features; Pathologic Features; Significance of Pathological Diagnoses of DIP or RBILD; Nonspecific Interstitial Pneumonia; Clinical Features; Pathologic Features; Pleuroparenchymal Fibroelastosis; Clinical Features; Pathologic Features; The Role of Surgical Lung Biopsy in Classification and Diagnosis of Idiopathic Interstitial Pneumonias "Pattern" Versus "Diagnosis" for Reporting the Results of Surgical Lung BiopsyDistinguishing Fibrotic NSIP from UIP; Role of Transbronchial Biopsies; Summary; References; Chapter 4: Imaging of Idiopathic Pulmonary Fibrosis; Introduction; Radiography; Technical Aspects of HRCT; Typical HRCT Pulmonary Findings; Accuracy of HRCT; Prognosis; Thoracic Complications of IPF; Atypical UIP on HRCT and How to Distinguish It from Other Common Fibrotic Lung Diseases; Summary; References; Chapter 5: Pulmonary Function Tests in Idiopathic Pulmonary Fibrosis; Pulmonary Function Tests in IPF FVC and DLco in Routine Clinical Practice and Clinical Trials: Strengths and PitfallsFuture Directions: Home Daily Spirometry in IPF; References; Chapter 6: The Role of Immunity and Inflammation in IPF Pathogenesis; Innate Immunity and Altered Host Defence Mechanisms; Chemotactic Cytokines; CXC Chemokines and Their Receptors; The Role of CXC Chemokines in Pulmonary Fibrosis; Vascular Remodelling in Pulmonary Fibrosis: The Role of CXC Chemokines; Macrophages; Neutrophils; Adaptive Immunity; Autoimmunity and IPF; Other Immunologically Active Cells; Inflammation and Acute Exacerbations of IPF
    Digital Access  Springer 2018