Bookeditors, Daniel J. Wallace, Bevra Hannahs Hahn ; associate editors, Mary K. Crow [and five others].
Summary: "For more than 50 years, Dubois’ Lupus Erythematosus and Related Syndromes has been recognized internationally as the go-to clinical reference on lupus and other connective tissue diseases. From basic scientific principles to practical points of clinical management, the updated 9th Edition provides extensive, authoritative coverage of systemic lupus erythematosus (SLE) and its related diseases in a logical, clearly written, user-friendly manner. It’s an ideal resource for rheumatologists and internal medicine practitioners who need a comprehensive clinical reference on all aspects of SLE, connective tissue diseases, and the antiphospholipid syndromes"--Publisher's description.
Contents:
History of lupus
Definition and classification of lupus and lupus-related disorders
The epidemiology of lupus
Overview of lupus pathogenesis
Genetics of human SLE
Epigenetics of lupus
The environment and the host
The innate immune system in SLE
B cells and generation of antibodies
T cells
Adaptive and innate immunoregulatory cells
Cytokines in lupus
Immunometabolism
Animal models in lupus
Abnormalities in immune complex clearance and apoptotic cell clearance
The role of complement in SLE
Apoptosis and inflammatory forms of cell death
Tissue damage in lupus : free radicals and fibrosis
Pathogenesis of fibrosis—the lung as a model
Pathogenesis of lupus nephritis
Pathogenesis of accelerated atherosclerosis and vascular injury in systemic lupus erythematosus
Pathogenesis of cutaneous lupus
Pathogenesis of neuropsychiatric lupus
Pathogenesis of antiphospholipid antibody syndrome
Pathogenesis of Sjögren's
Structure and derivation of autoantibodies
Antinuclear antibodies, antibodies to DNA, histones, and nucleosomes
Antibodies against ENA (SM, RNP, SSA, SSB)
Antibodies against C1q
Antilipoprotein and antiendothelial cell antibodies
Drug-induced lupus erythematosus
Overview and clinical presentation
Skin disease in cutaneous lupus erythematosus
The musculoskeletal system and bone metabolism
Lupus and the cardiopulmonary system
Lupus and the nervous system : clinical aspects, psychopathology, and imaging
Gastrointestinal and hepatic systems
Hematologic and lymphoid abnormalities in SLE
Neonatal lupus : pathogenesis and clinical approaches
Pregnancy and autoimmune disease, reproductive and hormonal issues
Systemic lupus erythematosus in childhood and adolescence
Clinical aspects of antiphospholipid syndrome
Lupus and infections
Ocular, aural, and oral manifestations of lupus
Clinical aspects of Sjögren's
Clinical application of serologic tests, serum protein abnormalities, and other clinical laboratory tests in systemic lupus erythematosus
Differential diagnosis and disease associations
Incomplete lupus, undifferentiated connective tissue disease, and mixed connective tissue disease
Clinical markers, metrics, indices, and clinical trials
Lupus biomarkers
Principles of therapy, local measures, and NSAIDs
Antimalarial medications
Systemic glucocorticoid therapy for SLE
Immunosuppressive drug therapy
Complementary and alternative medications, specialized and niche therapies
Adjunctive treatments and preventive measures
Targeted therapies in SLE
Management of cutaneous lupus erythematosus
Epidemiology and management of lupus nephritis
Management of Sjögren's
Socioeconomic and disability aspects
Prognosis and mortality of SLE.