BookYoshihiro Fukumoto, editor.
Summary: This book focuses on pulmonary arterial hypertension (PAH, Group 1) and chronic thromboembolic pulmonary hypertension (CTEPH, Group 4) among the various groups of pulmonary hypertension (PH) whose classification was updated into five major categories at the 5th World Symposium held in Nice, France, in 2013. Readers will find recent progress, methods, and up-to-date information on PH mechanisms, diagnostic images, and treatment in the management of PH. This volume, with contributions by leading researchers worldwide in the field, consists of five parts, starting with the fundamentals of PH, then pathophysiology and genetics, treatment, and right ventricular function.
Contents:
Part I Fundamentals of Pulmonary Hypertension
1. Clinical Classification
2. Diagnosis? Imagings
Part II Pathophysiology and Genetics
3. Pathogenic and Therapeutic Role of MicroRNA in Pulmonary Arterial Hypertension
4. Sex Hormones
5. Rho-Kinase
6. The Unique Property of the Pulmonary Artery Regard-ing the Smooth Muscle Effects of Proteinase-activated Receptor 1
The Possible Contribution to the Pathogenesis of Pulmonary Hypertension
7. Animal Models with Pulmonary Hypertension
8. Human Pathology
9. Pathophysiology and Genetics: BMPR2
Part III Treatment of Pulmonary Arterial Hypertension (PAH)
10. Prostacyclin
11. Targeting the NO-sGC-cGMP pathway in pulmonary arterial hypertension
12. Endothelin Receptor Antagonist
13. LUNG TRANSPLANTATION
Part IV Treatment of Chronic Thromboembolic Pulmonary Hypertension (CTEPH)
14. Medical Therapy for Chronic Thromboembolic Pulmonary Hypertension
15. Balloon Pulmonary Angioplasty
16. Pulmonary Endarterectomy for Chronic Thromboembolic Pulmonary Hypertension
Part V Right Ventricular Function
17. Right Ventricular Function.