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  • Book
    Shigekazu Nagata, Hiroyasu Nakano, editors.
    Summary: This volume focuses on apoptotic and non-apoptotic programmed cell death, including necroptosis, pyroptosis, and ferroptosis, and presents recent findings in the field. It discusses the crucial role that apoptotic and non-apoptotic cell death play in various pathological conditions, such as skin diseases, inflammatory bowel diseases, and virus infections. Further, it highlights the mechanisms underlying the recognition and clearance of dead cells, and the subsequent biological responses triggered by phagocytosed macrophages and factors released from dying cells. Offering insights into cell death, it is a valuable resource for researchers and clinicians developing novel strategies to treat various diseases that are closely associated with cell death.

    Contents:
    Prix fixe: Efferocytosis as a four-course meal
    Emerging roles for RIPKs in pathogen-induced cell death and host immunity
    Epithelial cell death and inflammation in skin
    IAPs and cell death
    Cellular FLICE-inhibitory protein regulates tissue homeostasis
    Lipid peroxidation dependent cell death regulated by GPx4 and ferroptosis
    Immune regulation by dead cell clearance.