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  • Book
    Gabi N. Waite, Maria Sheakley.
    Contents:
    Cellular physiology
    The nervous system
    Musculoskeletal and integumentary systems
    Blood and immune systems
    Cardiovascular and lymphatic systems
    Respiratory system
    Renal and urinary systems
    Gastrointestinal system
    Endocrine system
    Reproductive system
    Multisystem processes and disorders.
  • Article
    Lee F, Yanofsky C.
    Proc Natl Acad Sci U S A. 1977 Oct;74(10):4365-9.
    Transcription termination at the attenuators of the trp operons of Escherichia coli and Salmonella typhimurium was studied in vitro using DNA restriction fragments as templates. Readthrough transcription beyond the terminators occurred with 5 and 30% efficiency, respectively, in E. coli and S. typhimurium. This difference is correlated with the stability of proposed secondary structures of the respective trp leader transcripts. Secondary structure analyses of the two leader transcripts revealed a well-conserved pattern of RNA base paring. This and the possibility that trp leader RNA is translated suggest a model for regulation of transcription termination that is based on ribosome movement along the RNA and a shift between alternative RNA base-pairing configuration.
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