Bookedited by Ingeborg Huitinga and Maree J. Webster.
Summary: "Brain Banking, Volume 150, serves as the only book on the market offering comprehensive coverage of the functional realities of brain banking. It focuses on brain donor recruitment strategies, brain bank networks, ethical issues, brain dissection/tissue processing/tissue dissemination, neuropathological diagnosis, brain donor data, and techniques in brain tissue analysis. In accordance with massive initiatives, such as BRAIN and the EU Human Brain Project, abnormalities and potential therapeutic targets of neurological and psychiatric disorders need to be validated in human brain tissue, thus requiring substantial numbers of well characterized human brains of high tissue quality with neurological and psychiatric diseases"--Publisher's description.
Contents:
Section I. Brain donor recruitment strategies. The Netherlands Brain Bank for Psychiatry
Brain donation procedures in the sudden death brain bank in Edinburgh
Section II. Brain bank networks. Autism BrainNet
The NIH NeuroBioBank: Creating opportunities for human brain research
Section III. Ethical Aspects of Brain Banking and Management of Brain Banks
Design of a European code of conduct for brain banking
A review of brain biorepository management and operations
A new viewpoint: running a non-profit brain bank as a business
Section IV. Brain dissection, tissue processing and tissue dissemination. The New York Brain Bank of Columbia University: Practical highlights of 35 years of experience
Neurochemical markers as potential indicators of post-mortem tissue quality
Section V. Neuropathological diagnosis. Minimal neuropathological diagnosis for brain banking in the normal middle aged and aged brain and in neurodegenerative disorders
Brain donation at autopsy: Clinical characterization and toxicological analyses
Section VI. Brain donor data: clinical, genetic, radiologic and research data storage and mining. Information technology for brain banking
Collecting, storing and mining research data in a brain bank
What can we learn about brain donors? Use of clinical information in human postmortem brain research
The art of matching brain tissue from patients and controls for postmortem research
Section VII. Human brain tissue analyses: old and new techniques. Considerations for optimal use of postmortem human brains for molecular psychiatry: Lessons from schizophrenia
Epigenetic analysis of human brain tissue
Laser microdissection and gene expression profiling in the human postmortem brain
Purification of cells from fresh human brain tissue: Primary human glial cells
Proteomics and lipidomics in the human brain
3-D imaging in the post-mortem human brain with CLARITY and CUBIC
Neuronal life after death: Electrophysiological recordings from neurons in adult human brain tissue obtained through surgical resection or post-mortem
Post-mortem magnetic resonance imaging
Cyto- and receptorarchitectonic mapping of the human brain
Mapping pathological circuitry in schizophrenia